{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=IV+or+Oral+standard+of+care+antibiotics", "query": { "intervention": "IV or Oral standard of care antibiotics" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 12, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=IV+or+Oral+standard+of+care+antibiotics&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-08T05:29:55.391Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06859424", "title": "A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "AML (Acute Myelogenous Leukemia)", "Acute Lymphoid Leukemia (ALL)", "Acute Leukemia (Category)", "MDS (Myelodysplastic Syndrome)", "CML (Chronic Myelogenous Leukemia)", "CLL (Chronic Lymphocytic Leukemia)", "Prolymphocyctic Leukemia", "Chronic Myelomonocytic Leukemia (CMML)", "Myeloproliferative Neoplasm (MPN)", "Lymphoma", "Myelofibrosis" ], "interventions": [ { "name": "Conditioning Regimen A", "type": "DRUG" }, { "name": "Conditioning Regimen B", "type": "DRUG" }, { "name": "Conditioning Regimen C", "type": "DRUG" }, { "name": "Conditioning Regimen D", "type": "DRUG" }, { "name": "Conditioning Regimen E", "type": "DRUG" }, { "name": "Hematopoietic Cell Transplantation", "type": "PROCEDURE" }, { "name": "PTCy (50 mg/kg D3, D4)", "type": "DRUG" }, { "name": "PTCy (25 mg/kg D3, D4)", "type": "DRUG" }, { "name": "Post-transplant Tacrolimus", "type": "DRUG" }, { "name": "Post-transplant Mycophenolate mofetil", "type": "DRUG" }, { "name": "Post-transplant Abatacept", "type": "DRUG" }, { "name": "Post-transplant Ruxolitinib", "type": "DRUG" }, { "name": "Supportive Care: Growth Factors", "type": "DRUG" }, { "name": "Supportive Care: Blood Products", "type": "PROCEDURE" }, { "name": "Supportive Care: Infection Prophylaxis", "type": "OTHER" }, { "name": "Supportive Care: Intravenous immune globulin (IVIG)", "type": "OTHER" }, { "name": "Supportive Care: Seizure prophylaxis", "type": "DRUG" }, { "name": "Supportive Care: Monitoring and management of CRS", "type": "OTHER" }, { "name": "Supportive Care: Prophylaxis against infections", "type": "OTHER" }, { "name": "Supportive Care: Prophylaxis against infections", "type": "DRUG" }, { "name": "Supportive Care: Lipid elevations", "type": "OTHER" }, { "name": "Study treatment compliance", "type": "OTHER" }, { "name": "Prohibited Concomitant Therapy", "type": "OTHER" }, { "name": "Permitted Concomitant Therapy", "type": "OTHER" } ], "intervention_types": [ "DRUG", "PROCEDURE", "OTHER" ], "sponsor": "Center for International Blood and Marrow Transplant Research", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "66 Years", "sex": "ALL", "summary": "18 Years to 66 Years" }, "enrollment_count": 358, "start_date": "2025-07-25", "completion_date": "2028-06", "has_results": false, "last_update_posted_date": "2026-03-17", "last_synced_at": "2026-10-08T05:29:55.391Z", "location_count": 13, "location_summary": "Birmingham, Alabama • Duarte, California • Palo Alto, California + 10 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Duarte", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Westwood", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06859424" }, { "nct_id": "NCT05640336", "title": "Treatment of Acute Periprosthetic Joint Infection Comparing Single and Planned Double-Debridement Antibiotics and Implant Retention Followed by Chronic Antibiotic Suppression", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Periprosthetic Joint Infection" ], "interventions": [ { "name": "Single Debridement, Antibiotics and Implant Retention", "type": "PROCEDURE" }, { "name": "Planned Double Debridement, Antibiotics and Implant Retention", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 490, "start_date": "2023-03-03", "completion_date": "2032-03", "has_results": false, "last_update_posted_date": "2025-12-18", "last_synced_at": "2026-10-08T05:29:55.391Z", "location_count": 2, "location_summary": "Jacksonville, Florida • Rochester, Minnesota", "locations": [ { "city": "Jacksonville", "state": "Florida" }, { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT05640336" }, { "nct_id": "NCT05753215", "title": "Controlled Trial of Omadacycline Randomized Treatment Given for Bone and Joint Infection", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Bone Infection", "Joint Infection", "Bone and Joint Infection" ], "interventions": [ { "name": "Omadacycline Pill", "type": "DRUG" }, { "name": "Standard of Care", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 180, "start_date": "2023-05-09", "completion_date": "2026-06", "has_results": false, "last_update_posted_date": "2026-01-14", "last_synced_at": "2026-10-08T05:29:55.391Z", "location_count": 1, "location_summary": "Torrance, California", "locations": [ { "city": "Torrance", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05753215" }, { "nct_id": "NCT07148960", "title": "Does Staphylococcus Aureus Bacteremia Early Dual Therapy Improve Outcomes?", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Staphylococcus Aureus Bacteremia" ], "interventions": [ { "name": "Early Dual IV Antibiotic Therapy - MRSA", "type": "DRUG" }, { "name": "Early Dual IV Antibiotic Therapy - MSSA", "type": "DRUG" }, { "name": "Single Agent IV Antibiotic Therapy - MRSA", "type": "DRUG" }, { "name": "Single Agent IV Antibiotic Therapy - MSSA", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "West Virginia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 300, "start_date": "2025-09-15", "completion_date": "2027-07", "has_results": false, "last_update_posted_date": "2026-09-17", "last_synced_at": "2026-10-08T05:29:55.391Z", "location_count": 1, "location_summary": "Morgantown, West Virginia", "locations": [ { "city": "Morgantown", "state": "West Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT07148960" }, { "nct_id": "NCT03014687", "title": "Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Antibiotics", "Pituitary Adenoma" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Oral Antibiotics cefdinir or trimethoprim/sulfamethoxazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "St. Joseph's Hospital and Medical Center, Phoenix", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "84 Years", "sex": "ALL", "summary": "18 Years to 84 Years" }, "enrollment_count": 116, "start_date": "2017-07-01", "completion_date": "2019-07", "has_results": false, "last_update_posted_date": "2018-08-15", "last_synced_at": "2026-10-08T05:29:55.391Z", "location_count": 1, "location_summary": "Phoenix, Arizona", "locations": [ { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT03014687" }, { "nct_id": "NCT02692638", "title": "Trial Comparing Early Laparoscopic Enterolysis Versus Nonoperative Management for High-grade SBO", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Small Bowel Obstruction" ], "interventions": [ { "name": "Early laparoscopic enterolysis", "type": "PROCEDURE" }, { "name": "nonoperative management", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3, "start_date": "2016-02-02", "completion_date": "2016-10-13", "has_results": false, "last_update_posted_date": "2020-03-02", "last_synced_at": "2026-10-08T05:29:55.391Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT02692638" }, { "nct_id": "NCT05699174", "title": "PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Infections", "Infected Wound", "Nonunion of Fracture", "Injury Leg", "Amputation", "Internal Fixation; Complications, Infection or Inflammation", "Fracture", "Lower Extremity Fracture", "Antibiotic Side Effect" ], "interventions": [ { "name": "Standard of Care PO (oral) antibiotics", "type": "DRUG" }, { "name": "Standard of Care Intravenous (IV) antibiotics", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Major Extremity Trauma Research Consortium", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 250, "start_date": "2023-05-30", "completion_date": "2028-09-29", "has_results": false, "last_update_posted_date": "2026-09-11", "last_synced_at": "2026-10-08T05:29:55.391Z", "location_count": 13, "location_summary": "Indianapolis, Indiana • Baltimore, Maryland • Minneapolis, Minnesota + 9 more", "locations": [ { "city": "Indianapolis", "state": "Indiana" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Queens", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05699174" }, { "nct_id": "NCT01756924", "title": "Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Prosthetic Joint Infections of Hip", "Prosthetic Joint Infections of Knee", "Infected Spacers" ], "interventions": [ { "name": "CEM-102", "type": "DRUG" }, { "name": "IV or Oral standard of care antibiotics", "type": "DRUG" }, { "name": "Rifampin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arrevus Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 14, "start_date": "2012-12", "completion_date": "2014-07", "has_results": false, "last_update_posted_date": "2019-04-19", "last_synced_at": "2026-10-08T05:29:55.391Z", "location_count": 13, "location_summary": "Sarasota, Florida • Tamarac, Florida • Savannah, Georgia + 8 more", "locations": [ { "city": "Sarasota", "state": "Florida" }, { "city": "Tamarac", "state": "Florida" }, { "city": "Savannah", "state": "Georgia" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01756924" }, { "nct_id": "NCT06239272", "title": "NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Adipocytic Neoplasm", "Liposarcoma", "Atypical Fibroxanthoma", "Angiomatoid Fibrous Histiocytoma", "Fibrosarcoma NOS", "Myxofibrosarcoma", "Angiosarcoma", "Osteosarcoma, Extraskeletal", "Dedifferentiated Liposarcoma", "Myxoid Liposarcoma", "Pleomorphic Liposarcoma", "Myxoid Pleomorphic Liposarcoma", "Low Grade Fibromyxoid Sarcoma", "Sclerosing Epithelioid Fibrosarcoma", "Malignant Tenosynovial Giant Cell Tumor of Soft Tissue", "Epithelioid Hemangioendothelioma", "Glomus Tumor", "Inflammatory Leiomyosarcoma", "Leiomyosarcoma", "Ossifying Fibromyxoid Tumor, Malignant", "Myoepithelioma", "Synovial Sarcoma", "Epithelioid Sarcoma", "Perineurioma, Malignant", "Clear Cell Sarcoma", "Extraskeletal Myxoid Chondrosarcoma", "Granular Cell Tumor, Malignant", "Melanotic Malignant Nerve Sheath Tumor", "Malignant Peripheral Nerve Sheath Tumor", "Perivascular Epithelioid Tumor, Malignant", "Intimal Sarcoma", "Myoepithelial Carcinoma", "Undifferentiated Sarcoma", "Pleomorphic Sarcoma, Undifferentiated", "Round Cell Sarcoma, Undifferentiated", "NTRK-Rearranged Spindle Cell Neoplasm", "Phosphaturic Mesenchymal Tumor, Malignant", "Round Cell Sarcoma", "Well Differentiated Liposarcoma", "Giant Cell Tumor of Soft Parts NOS", "Low Grade Myofibroblastic Sarcoma", "Dermatofibrosarcoma Protuberans, Fibrosarcomatous" ], "interventions": [ { "name": "Surgical resection", "type": "PROCEDURE" }, { "name": "Proton beam radiation therapy", "type": "RADIATION" }, { "name": "Pazopanib", "type": "DRUG" }, { "name": "Ifosfamide", "type": "DRUG" }, { "name": "Doxorubicin", "type": "DRUG" }, { "name": "Selinexor", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "RADIATION", "DRUG" ], "sponsor": "St. Jude Children's Research Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "30 Years", "sex": "ALL", "summary": "Up to 30 Years" }, "enrollment_count": 139, "start_date": "2024-03-27", "completion_date": "2037-06", "has_results": false, "last_update_posted_date": "2026-08-03", "last_synced_at": "2026-10-08T05:29:55.391Z", "location_count": 7, "location_summary": "Atlanta, Georgia • Chicago, Illinois • Baton Rouge, Louisiana + 4 more", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Baton Rouge", "state": "Louisiana" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT06239272" }, { "nct_id": "NCT06692179", "title": "An Open-Label, Pilot Clinical Trial To Test The Safety And Feasibility Of A Suspension of Freeze-dried Microbiota In Patients Undergoing Colon Resection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Recurrent Clostridioides Difficile Infection", "Colonic Surgery" ], "interventions": [ { "name": "Orally administered preparation of fecal microbiota (MTP-101P)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 21, "start_date": "2025-02-18", "completion_date": "2026-06-08", "has_results": false, "last_update_posted_date": "2026-09-03", "last_synced_at": "2026-10-08T05:29:55.391Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT06692179" } ] }