{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=IV+tobramycin", "query": { "intervention": "IV tobramycin" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 14, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=IV+tobramycin&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-07T13:11:06.871Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02819856", "title": "SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Ototoxicity" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "SPI-1005 Ebselen 200mg Capsule x1", "type": "DRUG" }, { "name": "SPI-1005 Ebselen 200mg Capsule x2", "type": "DRUG" }, { "name": "SPI-1005 Ebselen 200mg Capsule x3", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sound Pharmaceuticals, Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 35, "start_date": "2017-07-21", "completion_date": "2023-04-07", "has_results": true, "last_update_posted_date": "2026-07-16", "last_synced_at": "2026-09-07T13:11:06.871Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02819856" }, { "nct_id": "NCT05361941", "title": "Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth in/Near Infected Bone Cavities", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Periprosthetic Joint Infections" ], "interventions": [ { "name": "EP Granules with Tobramycin", "type": "DEVICE" }, { "name": "empty voids", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Elute, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "22 Years", "maximum_age": null, "sex": "ALL", "summary": "22 Years and older" }, "enrollment_count": 204, "start_date": "2023-08-31", "completion_date": "2029-12-31", "has_results": false, "last_update_posted_date": "2026-07-14", "last_synced_at": "2026-09-07T13:11:06.871Z", "location_count": 16, "location_summary": "Los Angeles, California • Washington D.C., District of Columbia • Skokie, Illinois + 12 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Skokie", "state": "Illinois" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT05361941" }, { "nct_id": "NCT02099240", "title": "Patients Response to Early Switch To Oral:Osteomyelitis Study", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Osteomyelitis" ], "interventions": [ { "name": "oral antibiotics", "type": "DRUG" }, { "name": "intravenous antibiotics", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Julio Ramirez", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 11, "start_date": "2014-03-06", "completion_date": "2018-11-07", "has_results": false, "last_update_posted_date": "2021-04-06", "last_synced_at": "2026-09-07T13:11:06.871Z", "location_count": 1, "location_summary": "Louisville, Kentucky", "locations": [ { "city": "Louisville", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT02099240" }, { "nct_id": "NCT00153634", "title": "Standard vs. Biofilm Susceptibility Testing in Cystic Fibrosis (CF)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cystic Fibrosis", "Chronic Bronchitis" ], "interventions": [ { "name": "IV amikacin", "type": "DRUG" }, { "name": "PO azithromycin", "type": "DRUG" }, { "name": "IV ceftazidime", "type": "DRUG" }, { "name": "PO ciprofloxacin", "type": "DRUG" }, { "name": "IV meropenem", "type": "DRUG" }, { "name": "IV piperacillin-tazobactam", "type": "DRUG" }, { "name": "IV ticarcillin-clavulanate", "type": "DRUG" }, { "name": "IV tobramycin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Seattle Children's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "14 Years", "maximum_age": null, "sex": "ALL", "summary": "14 Years and older" }, "enrollment_count": 75, "start_date": "2004-03", "completion_date": "2007-11", "has_results": false, "last_update_posted_date": "2008-03-13", "last_synced_at": "2026-09-07T13:11:06.871Z", "location_count": 8, "location_summary": "Iowa City, Iowa • St Louis, Missouri • Cincinnati, Ohio + 4 more", "locations": [ { "city": "Iowa City", "state": "Iowa" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "Columbus", "state": "Ohio" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00153634" }, { "nct_id": "NCT02918409", "title": "IV Colistin for Pulmonary Exacerbations: Improving Safety and Efficacy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cystic Fibrosis" ], "interventions": [ { "name": "Colistin", "type": "DRUG" }, { "name": "Tobramycin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Jewish Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 51, "start_date": "2016-08-26", "completion_date": "2021-11-22", "has_results": true, "last_update_posted_date": "2026-04-28", "last_synced_at": "2026-09-07T13:11:06.871Z", "location_count": 1, "location_summary": "Denver, Colorado", "locations": [ { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT02918409" }, { "nct_id": "NCT02015663", "title": "Tobramycin Inhalation Powder (TIP) Administered Once Daily Continuously Versus TIP Administered BID in 28 Day on / 28 Day Off Cycles", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cystic Fibrosis" ], "interventions": [ { "name": "Tobramycin Inhalation Powder", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": null, "sex": "ALL", "summary": "6 Years and older" }, "enrollment_count": 32, "start_date": "2014-01", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2017-03-29", "last_synced_at": "2026-09-07T13:11:06.871Z", "location_count": 21, "location_summary": "Mobile, Alabama • Los Angeles, California • Sacramento, California + 18 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Ventura", "state": "California" }, { "city": "Altamonte Springs", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02015663" }, { "nct_id": "NCT01775137", "title": "Ext. Long-term Safety Study in CF Patients: Single Arm TIP", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Long-term Safety of TIP" ], "interventions": [ { "name": "TBM100", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": null, "sex": "ALL", "summary": "6 Years and older" }, "enrollment_count": 45, "start_date": "2013-02", "completion_date": "2014-11", "has_results": true, "last_update_posted_date": "2015-11-06", "last_synced_at": "2026-09-07T13:11:06.871Z", "location_count": 4, "location_summary": "Akron, Ohio • Charleston, South Carolina • Dallas, Texas + 1 more", "locations": [ { "city": "Akron", "state": "Ohio" }, { "city": "Charleston", "state": "South Carolina" }, { "city": "Dallas", "state": "Texas" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01775137" }, { "nct_id": "NCT06293352", "title": "Real-component vs All-cement Articulating Spacers for Periprosthetic Knee Infection", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Prosthetic-joint Infection", "Knee Infection", "Arthroplasty Complications", "Joint Infection", "Arthroplasty, Replacement, Knee" ], "interventions": [ { "name": "All-cement articulating spacer", "type": "DEVICE" }, { "name": "Durable, real-component articulating spacer", "type": "DEVICE" }, { "name": "Rigid Spacer", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 153, "start_date": "2024-08-08", "completion_date": "2028-08", "has_results": false, "last_update_posted_date": "2026-08-24", "last_synced_at": "2026-09-07T13:11:06.871Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT06293352" }, { "nct_id": "NCT04678154", "title": "Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Post Operative Surgical Site Infection" ], "interventions": [ { "name": "Standard of care", "type": "DRUG" }, { "name": "Vancomycin and Tobramycin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Major Extremity Trauma Research Consortium", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "18 Years to 64 Years" }, "enrollment_count": 600, "start_date": "2021-05-07", "completion_date": "2029-03-31", "has_results": false, "last_update_posted_date": "2026-07-22", "last_synced_at": "2026-09-07T13:11:06.871Z", "location_count": 31, "location_summary": "Redwood City, California • San Francisco, California • Aurora, Colorado + 25 more", "locations": [ { "city": "Redwood City", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "West Palm Beach", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04678154" }, { "nct_id": "NCT00707239", "title": "Study Evaluating Safety and Efficacy of Tigecycline Versus Imipenem/Cilastatin Subjects With Hospital-Acquired Pneumonia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pneumonia, Bacterial" ], "interventions": [ { "name": "tigecycline", "type": "DRUG" }, { "name": "imipenem/cilastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 108, "start_date": "2008-12", "completion_date": "2011-06", "has_results": true, "last_update_posted_date": "2012-07-10", "last_synced_at": "2026-09-07T13:11:06.871Z", "location_count": 3, "location_summary": "Louisville, Kentucky • Omaha, Nebraska • Morgantown, West Virginia", "locations": [ { "city": "Louisville", "state": "Kentucky" }, { "city": "Omaha", "state": "Nebraska" }, { "city": "Morgantown", "state": "West Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00707239" } ] }