{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Icatibant", "query": { "intervention": "Icatibant" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 16, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Icatibant&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-06T19:41:09.619Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01457430", "title": "Efficacy, Safety and Tolerability of Icatibant for the Treatment of HAE", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hereditary Angioedema" ], "interventions": [ { "name": "Icatibant", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 19, "start_date": "2011-12", "completion_date": "2014-04", "has_results": true, "last_update_posted_date": "2016-10-18", "last_synced_at": "2026-09-06T19:41:09.619Z", "location_count": 5, "location_summary": "La Jolla, California • Los Angeles, California • Wheaton, Maryland + 2 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Wheaton", "state": "Maryland" }, { "city": "Hershey", "state": "Pennsylvania" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01457430" }, { "nct_id": "NCT00303056", "title": "Efficacy and Safety Study of Intra-articular Multiple Doses of Icatibant in Patients With Painful Knee Osteoarthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Joint Disease" ], "interventions": [ { "name": "HOE140 Icatibant", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 590, "start_date": "2006-02", "completion_date": "2007-07", "has_results": false, "last_update_posted_date": "2012-02-17", "last_synced_at": "2026-09-06T19:41:09.619Z", "location_count": 1, "location_summary": "Bridgewater, New Jersey", "locations": [ { "city": "Bridgewater", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00303056" }, { "nct_id": "NCT00912093", "title": "A Study of Icatibant in Patients With Acute Attacks of Hereditary Angioedema (FAST-3)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hereditary Angioedema" ], "interventions": [ { "name": "Icatibant", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shire", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 98, "start_date": "2009-07-16", "completion_date": "2010-10-01", "has_results": true, "last_update_posted_date": "2021-06-11", "last_synced_at": "2026-09-06T19:41:09.619Z", "location_count": 39, "location_summary": "Alabaster, Alabama • Birmingham, Alabama • Scottsdale, Arizona + 35 more", "locations": [ { "city": "Alabaster", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Granada Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00912093" }, { "nct_id": "NCT01919801", "title": "Blinded Safety & Efficacy Placebo Controlled Study of Icatibant for Angiotensin Converting Enzyme Inhibitor Induced Angioedema", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Angiotensin Converting Enzyme Inhibitor Induced Angioedema" ], "interventions": [ { "name": "Icatibant", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shire", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 118, "start_date": "2013-12-02", "completion_date": "2015-08-22", "has_results": true, "last_update_posted_date": "2021-06-08", "last_synced_at": "2026-09-06T19:41:09.619Z", "location_count": 43, "location_summary": "La Jolla, California • Washington D.C., District of Columbia • Gainesville, Florida + 31 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01919801" }, { "nct_id": "NCT00097695", "title": "Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Angioedema" ], "interventions": [ { "name": "Icatibant", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shire", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 84, "start_date": "2004-12-28", "completion_date": "2006-07-17", "has_results": true, "last_update_posted_date": "2021-06-09", "last_synced_at": "2026-09-06T19:41:09.619Z", "location_count": 1, "location_summary": "Washington D.C., District of Columbia", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00097695" }, { "nct_id": "NCT03177798", "title": "Mitochondria and Chronic Kidney Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hemodialysis-Induced Symptom", "Mitochondrial Diseases" ], "interventions": [ { "name": "Icatibant", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "78 Years", "sex": "ALL", "summary": "18 Years to 78 Years" }, "enrollment_count": 11, "start_date": "2017-08-01", "completion_date": "2018-12-31", "has_results": true, "last_update_posted_date": "2019-10-29", "last_synced_at": "2026-09-06T19:41:09.619Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03177798" }, { "nct_id": "NCT04488081", "title": "I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "COVID-19" ], "interventions": [ { "name": "Remdesivir", "type": "DRUG" }, { "name": "Imatinib Mesylate", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Cenicriviroc", "type": "DRUG" }, { "name": "Icatibant", "type": "DRUG" }, { "name": "Apremilast", "type": "DRUG" }, { "name": "dornase alfa", "type": "BIOLOGICAL" }, { "name": "Celecoxib", "type": "DRUG" }, { "name": "Famotidine", "type": "DRUG" }, { "name": "IC14", "type": "BIOLOGICAL" }, { "name": "Aviptadil", "type": "DRUG" }, { "name": "narsoplimab", "type": "BIOLOGICAL" }, { "name": "Cyproheptadine", "type": "DRUG" }, { "name": "Cyclosporine", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BIOLOGICAL" ], "sponsor": "QuantumLeap Healthcare Collaborative", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1500, "start_date": "2020-07-31", "completion_date": "2030-07-31", "has_results": false, "last_update_posted_date": "2026-03-16", "last_synced_at": "2026-09-06T19:41:09.619Z", "location_count": 36, "location_summary": "Birmingham, Alabama • Davis, California • Irvine, California + 30 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Davis", "state": "California" }, { "city": "Irvine", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04488081" }, { "nct_id": "NCT00223704", "title": "Bradykinin Receptor Antagonism During Cardiopulmonary Bypass", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Cardiopulmonary Bypass", "Inflammation", "Fibrinolysis", "Surgery" ], "interventions": [ { "name": "HOE 140", "type": "DRUG" }, { "name": "Aminocaproic Acid", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 150, "start_date": "2006-05", "completion_date": "2012-06", "has_results": true, "last_update_posted_date": "2013-11-25", "last_synced_at": "2026-09-06T19:41:09.619Z", "location_count": 2, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00223704" }, { "nct_id": "NCT01574248", "title": "Effect of Bradykinin Receptor Antagonism on ACE Inhibitor-associated Angioedema", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "ACE Inhibitor-associated Angioedema" ], "interventions": [ { "name": "icatibant", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 33, "start_date": "2011-08", "completion_date": "2016-02", "has_results": true, "last_update_posted_date": "2017-02-17", "last_synced_at": "2026-09-06T19:41:09.619Z", "location_count": 2, "location_summary": "San Diego, California • Nashville, Tennessee", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT01574248" }, { "nct_id": "NCT05834777", "title": "Prevention of Intradialytic Hypotension by Inhibiting Bradykinin B2 Receptor", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Intradialytic Hypotension" ], "interventions": [ { "name": "Icatibant", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 26, "start_date": "2023-12-11", "completion_date": "2026-11-01", "has_results": false, "last_update_posted_date": "2026-04-15", "last_synced_at": "2026-09-06T19:41:09.619Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT05834777" } ] }