{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Information+Letter",
    "query": {
      "intervention": "Information Letter"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 124,
    "total_pages": 13,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Information+Letter&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-09T05:56:46.902Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00746668",
      "title": "A Multi-Center Study of Reading Rehabilitation in Macular Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Age Related Maculopathy",
        "Retinal Degeneration"
      ],
      "interventions": [
        {
          "name": "Module 1: Visual Awareness and Eccentric Viewing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Module 2: Control of Reading Eye Movements",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Module 3: Reading Practice with RSVP",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2008-08",
      "completion_date": "2012-09",
      "has_results": true,
      "last_update_posted_date": "2015-02-27",
      "last_synced_at": "2026-09-09T05:56:46.902Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00746668"
    },
    {
      "nct_id": "NCT00101868",
      "title": "Value of Technology to Transfer Discharge Information",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Information Dissemination",
        "Interprofessional Relations"
      ],
      "interventions": [
        {
          "name": "Discharge communication software",
          "type": "DEVICE"
        },
        {
          "name": "Usual care discharge process",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Agency for Healthcare Research and Quality (AHRQ)",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 631,
      "start_date": "2004-12",
      "completion_date": "2007-08",
      "has_results": true,
      "last_update_posted_date": "2012-05-15",
      "last_synced_at": "2026-09-09T05:56:46.902Z",
      "location_count": 1,
      "location_summary": "Peoria, Illinois",
      "locations": [
        {
          "city": "Peoria",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00101868"
    },
    {
      "nct_id": "NCT03300180",
      "title": "Caregiver Outcomes of Alzheimer's Disease Screening",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Collaborative Dementia Care Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Screening Only",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 1822,
      "start_date": "2018-10-15",
      "completion_date": "2023-09-30",
      "has_results": true,
      "last_update_posted_date": "2025-05-02",
      "last_synced_at": "2026-09-09T05:56:46.902Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03300180"
    },
    {
      "nct_id": "NCT00886730",
      "title": "Primary Care Patients With Depression for Internet-Based Social Support",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Simple Card",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Centered Brochure",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Physician's endorsement",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2008-10",
      "completion_date": "2011-05",
      "has_results": false,
      "last_update_posted_date": "2012-12-17",
      "last_synced_at": "2026-09-09T05:56:46.902Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00886730"
    },
    {
      "nct_id": "NCT03850431",
      "title": "Using Behavioral Economics to Enhance Appointment Reminders and Reduce Missed Visits",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Appointment Reminders"
      ],
      "interventions": [
        {
          "name": "Social Norms + Behavioral Instructions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Caring + Consequences for Others + Behavioral Instructions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Caring + Consequences for Self + Behavioral Instructions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Caring + Consequences for Others + Consequences for Self + Social Norms + Behavioral Instructions",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34516,
      "start_date": "2019-12-17",
      "completion_date": "2021-10-14",
      "has_results": true,
      "last_update_posted_date": "2024-04-19",
      "last_synced_at": "2026-09-09T05:56:46.902Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03850431"
    },
    {
      "nct_id": "NCT03856593",
      "title": "Encouraging Judicious Prescribing of Opioids in Los Angeles County",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance-Related Disorders"
      ],
      "interventions": [
        {
          "name": "Standard letter",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Comparator letter",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 541,
      "start_date": "2019-04-05",
      "completion_date": "2021-08-08",
      "has_results": true,
      "last_update_posted_date": "2023-03-28",
      "last_synced_at": "2026-09-09T05:56:46.902Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03856593"
    },
    {
      "nct_id": "NCT06941519",
      "title": "Addressing Social Needs to Improve Health in Adults With Multiple Chronic Conditions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Chronic Conditions",
        "Social Needs",
        "Care Gaps",
        "Navigation"
      ],
      "interventions": [
        {
          "name": "Telephonic Outreach",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Virtual Outreach",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 800,
      "start_date": "2025-09-01",
      "completion_date": "2029-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-05",
      "last_synced_at": "2026-09-09T05:56:46.902Z",
      "location_count": 1,
      "location_summary": "Pleasanton, California",
      "locations": [
        {
          "city": "Pleasanton",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06941519"
    },
    {
      "nct_id": "NCT00810771",
      "title": "Evaluating a Preference-based Intervention for Increasing Colorectal Cancer Screening",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colorectal Neoplasms"
      ],
      "interventions": [
        {
          "name": "Standard Information",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Preference-tailored Information",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "78 Years",
        "sex": "ALL",
        "summary": "50 Years to 78 Years"
      },
      "enrollment_count": 466,
      "start_date": "2009-02",
      "completion_date": "2012-08",
      "has_results": true,
      "last_update_posted_date": "2015-06-02",
      "last_synced_at": "2026-09-09T05:56:46.902Z",
      "location_count": 2,
      "location_summary": "Ann Arbor, Michigan • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00810771"
    },
    {
      "nct_id": "NCT05676099",
      "title": "TSC Biosample Repository and Natural History Database",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tuberous Sclerosis",
        "Lymphangioleiomyomatosis"
      ],
      "interventions": [
        {
          "name": "Phlebotomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Buccal (cheek) swab",
          "type": "PROCEDURE"
        },
        {
          "name": "Genetic Testing",
          "type": "GENETIC"
        },
        {
          "name": "Tissue donation after routine clinical procedure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "GENETIC",
        "OTHER"
      ],
      "sponsor": "National Tuberous Sclerosis Association",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 5000,
      "start_date": "2016-01",
      "completion_date": "2050-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-24",
      "last_synced_at": "2026-09-09T05:56:46.902Z",
      "location_count": 24,
      "location_summary": "Birmingham, Alabama • Loma Linda, California • Los Angeles, California + 19 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05676099"
    },
    {
      "nct_id": "NCT01827215",
      "title": "Randomized Control Trial of a Virtual Patient Advocate for Preconception Care",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Preconception Care"
      ],
      "interventions": [
        {
          "name": "Virtual Patient Advocate (VPA)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Boston Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "34 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 34 Years · Female only"
      },
      "enrollment_count": 528,
      "start_date": "2013-09",
      "completion_date": "2019-01",
      "has_results": false,
      "last_update_posted_date": "2019-10-03",
      "last_synced_at": "2026-09-09T05:56:46.902Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01827215"
    }
  ]
}