{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Inhaled+loxapine",
    "query": {
      "intervention": "Inhaled loxapine"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 18,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Inhaled+loxapine&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-11T20:15:41.442Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00489476",
      "title": "Staccato Loxapine in Migraine (in Clinic)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Staccato Loxapine",
          "type": "DRUG"
        },
        {
          "name": "Staccato Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alexza Pharmaceuticals, Inc.",
      "sponsor_class": "UNKNOWN",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 168,
      "start_date": "2007-06",
      "completion_date": "2007-12",
      "has_results": true,
      "last_update_posted_date": "2017-07-06",
      "last_synced_at": "2026-09-11T20:15:41.442Z",
      "location_count": 1,
      "location_summary": "Wellesley Hills, Massachusetts",
      "locations": [
        {
          "city": "Wellesley Hills",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00489476"
    },
    {
      "nct_id": "NCT00873769",
      "title": "Staccato Loxapine PK in Smokers and Nonsmokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Smoking, Cigarette"
      ],
      "interventions": [
        {
          "name": "Inhaled Loxapine 10 mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alexza Pharmaceuticals, Inc.",
      "sponsor_class": "UNKNOWN",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "20 Years to 50 Years"
      },
      "enrollment_count": 35,
      "start_date": "2009-04",
      "completion_date": "2009-06",
      "has_results": false,
      "last_update_posted_date": "2017-03-15",
      "last_synced_at": "2026-09-11T20:15:41.442Z",
      "location_count": 1,
      "location_summary": "Evansville, Indiana",
      "locations": [
        {
          "city": "Evansville",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00873769"
    },
    {
      "nct_id": "NCT01877642",
      "title": "ADASUVE-Lorazepam Drug-Drug Interaction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Lorazepam 1 mg IM",
          "type": "DRUG"
        },
        {
          "name": "Inhaled loxapine 10 mg",
          "type": "DRUG"
        },
        {
          "name": "Inhaled Placebo",
          "type": "DRUG"
        },
        {
          "name": "Placebo IM",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alexza Pharmaceuticals, Inc.",
      "sponsor_class": "UNKNOWN",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 22,
      "start_date": "2013-06",
      "completion_date": "2013-07",
      "has_results": true,
      "last_update_posted_date": "2017-12-13",
      "last_synced_at": "2026-09-11T20:15:41.442Z",
      "location_count": 1,
      "location_summary": "Evansville, Indiana",
      "locations": [
        {
          "city": "Evansville",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01877642"
    },
    {
      "nct_id": "NCT00874237",
      "title": "Staccato Loxapine Thorough QT/QTc Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Thorough QT/QTc Study"
      ],
      "interventions": [
        {
          "name": "Inhaled loxapine",
          "type": "DRUG"
        },
        {
          "name": "Inhaled placebo",
          "type": "DRUG"
        },
        {
          "name": "Oral moxifloxacin",
          "type": "DRUG"
        },
        {
          "name": "Oral placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Nova Pneuma Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 48,
      "start_date": "2009-04",
      "completion_date": "2009-06",
      "has_results": true,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-09-11T20:15:41.442Z",
      "location_count": 1,
      "location_summary": "Evansville, Indiana",
      "locations": [
        {
          "city": "Evansville",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00874237"
    },
    {
      "nct_id": "NCT00890175",
      "title": "Staccato Loxapine Pulmonary Safety in Patients With Asthma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Asthma"
      ],
      "interventions": [
        {
          "name": "Inhaled loxapine @ 0 & 10 h",
          "type": "DRUG"
        },
        {
          "name": "Inhaled placebo @ 2 & 10 hours",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alexza Pharmaceuticals, Inc.",
      "sponsor_class": "UNKNOWN",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 52,
      "start_date": "2009-05",
      "completion_date": "2009-08",
      "has_results": false,
      "last_update_posted_date": "2017-03-15",
      "last_synced_at": "2026-09-11T20:15:41.442Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00890175"
    },
    {
      "nct_id": "NCT00721955",
      "title": "Staccato Loxapine in Agitated Patients With Bipolar Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Bipolar I Disorder"
      ],
      "interventions": [
        {
          "name": "Inhaled Placebo",
          "type": "DRUG"
        },
        {
          "name": "Inhaled loxapine 5 mg",
          "type": "DRUG"
        },
        {
          "name": "Inhaled loxapine 10 mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alexza Pharmaceuticals, Inc.",
      "sponsor_class": "UNKNOWN",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 314,
      "start_date": "2008-07",
      "completion_date": "2008-10",
      "has_results": true,
      "last_update_posted_date": "2017-07-26",
      "last_synced_at": "2026-09-11T20:15:41.442Z",
      "location_count": 6,
      "location_summary": "Escondido, California • Garden Grove, California • Atlanta, Georgia + 3 more",
      "locations": [
        {
          "city": "Escondido",
          "state": "California"
        },
        {
          "city": "Garden Grove",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00721955"
    },
    {
      "nct_id": "NCT00628589",
      "title": "Staccato Loxapine in Agitated Patients With Schizophrenia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Patients With Schizophrenia and Acute Agitation"
      ],
      "interventions": [
        {
          "name": "Inhaled loxapine 5 mg",
          "type": "DRUG"
        },
        {
          "name": "Inhaled loxapine 10 mg",
          "type": "DRUG"
        },
        {
          "name": "Inhaled placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alexza Pharmaceuticals, Inc.",
      "sponsor_class": "UNKNOWN",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 344,
      "start_date": "2008-02",
      "completion_date": "2008-05",
      "has_results": true,
      "last_update_posted_date": "2017-07-26",
      "last_synced_at": "2026-09-11T20:15:41.442Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00628589"
    },
    {
      "nct_id": "NCT00444028",
      "title": "Staccato Loxapine Single Dose PK",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Schizophrenia"
      ],
      "interventions": [
        {
          "name": "inhaled Loxapine 0.625 mg",
          "type": "DRUG"
        },
        {
          "name": "inhaled Loxapine 1.25 mg",
          "type": "DRUG"
        },
        {
          "name": "inhaled Loxapine 2.5 mg",
          "type": "DRUG"
        },
        {
          "name": "inhaled Loxapine 5 mg",
          "type": "DRUG"
        },
        {
          "name": "inhaled Loxapine 10 mg",
          "type": "DRUG"
        },
        {
          "name": "inhaled Placebo (0 mg)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alexza Pharmaceuticals, Inc.",
      "sponsor_class": "UNKNOWN",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 50,
      "start_date": "2005-09",
      "completion_date": "2005-11",
      "has_results": true,
      "last_update_posted_date": "2018-11-20",
      "last_synced_at": "2026-09-11T20:15:41.442Z",
      "location_count": 1,
      "location_summary": "Evansville, Indiana",
      "locations": [
        {
          "city": "Evansville",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00444028"
    },
    {
      "nct_id": "NCT00543062",
      "title": "Staccato Prochlorperazine Thorough QT/QTc",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cardiotoxicity"
      ],
      "interventions": [
        {
          "name": "Inhaled placebo",
          "type": "DRUG"
        },
        {
          "name": "Oral placebo",
          "type": "DRUG"
        },
        {
          "name": "Inhaled prochlorperazine 5 mg",
          "type": "DRUG"
        },
        {
          "name": "Inhaled prochlorperazine 10 mg",
          "type": "DRUG"
        },
        {
          "name": "Oral moxifloxacin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alexza Pharmaceuticals, Inc.",
      "sponsor_class": "UNKNOWN",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 48,
      "start_date": "2007-10",
      "completion_date": "2007-12",
      "has_results": true,
      "last_update_posted_date": "2019-03-11",
      "last_synced_at": "2026-09-11T20:15:41.442Z",
      "location_count": 1,
      "location_summary": "Evansville, Indiana",
      "locations": [
        {
          "city": "Evansville",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00543062"
    },
    {
      "nct_id": "NCT00610727",
      "title": "Staccato Prochlorperazine Single Dose PK Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Prochlorperazine 0.5 mg IV over 5 sec",
          "type": "DRUG"
        },
        {
          "name": "Inhaled prochlorperazine 0.625 mg",
          "type": "DRUG"
        },
        {
          "name": "Inhaled prochlorperazine 1.25 mg",
          "type": "DRUG"
        },
        {
          "name": "Inhaled prochlorperazine 2.5 mg",
          "type": "DRUG"
        },
        {
          "name": "Inhaled prochlorperazine 5 mg",
          "type": "DRUG"
        },
        {
          "name": "Inhaled prochlorperazine 10 mg",
          "type": "DRUG"
        },
        {
          "name": "Inhaled placebo",
          "type": "DRUG"
        },
        {
          "name": "Prochlorperazine 10 mg IV over 5 sec",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Nova Pneuma Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 54,
      "start_date": "2004-08",
      "completion_date": "2004-10",
      "has_results": true,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-09-11T20:15:41.442Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00610727"
    }
  ]
}