{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intensive+medical+therapy",
    "query": {
      "intervention": "Intensive medical therapy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 102,
    "total_pages": 11,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intensive+medical+therapy&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-12T16:10:05.369Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05766631",
      "title": "Treating Polysubstance Use Using a Novel Digital Technology",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Opioid Use",
        "Opioid Use Disorder",
        "Cocaine Use",
        "Cocaine Use Disorder"
      ],
      "interventions": [
        {
          "name": "DynamiCare Health",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Methadone Treatment-As-Usual",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Friends Research Institute, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 240,
      "start_date": "2023-07-26",
      "completion_date": "2027-09-29",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-09-12T16:10:05.369Z",
      "location_count": 5,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05766631"
    },
    {
      "nct_id": "NCT04166630",
      "title": "Diagnosing Intensive Care Unit (ICU) Acquired Weakness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ICU Acquired Weakness"
      ],
      "interventions": [
        {
          "name": "Clinical Electrical Stimulator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2021-02-02",
      "completion_date": "2021-06-11",
      "has_results": true,
      "last_update_posted_date": "2022-08-19",
      "last_synced_at": "2026-09-12T16:10:05.369Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04166630"
    },
    {
      "nct_id": "NCT02465177",
      "title": "Tailoring Screening, Brief Intervention, and Referral to Treatment for Medical ICU Survivors",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Unhealthy Alcohol Use",
        "Alcohol Use Disorders"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "MALE",
        "summary": "18 Years to 100 Years · Male only"
      },
      "enrollment_count": 28,
      "start_date": "2014-07",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2021-02-18",
      "last_synced_at": "2026-09-12T16:10:05.369Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02465177"
    },
    {
      "nct_id": "NCT05489068",
      "title": "Motivational Interviewing at Intake vs Intake as Usual on Client Engagement in Addiction Treatment",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Substance-Related Disorders",
        "Treatment Adherence"
      ],
      "interventions": [
        {
          "name": "Motivational Interviewing at Intake (MII)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Intake as Usual (IAU)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of New Mexico",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2022-03-16",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-09",
      "last_synced_at": "2026-09-12T16:10:05.369Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05489068"
    },
    {
      "nct_id": "NCT03440918",
      "title": "Impact of a Procalcitonin Testing and Treatment Algorithm on Antibiotic Use and Outcomes in the Pediatric Intensive Care Unit",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sepsis",
        "Procalcitonin",
        "Antimicrobial Stewardship"
      ],
      "interventions": [
        {
          "name": "Procalcitonin-Guided Antimicrobial Stewardship",
          "type": "OTHER"
        },
        {
          "name": "Baseline Antimicrobial Stewardship",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Hours",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "2 Hours to 17 Years"
      },
      "enrollment_count": 271,
      "start_date": "2018-02-12",
      "completion_date": "2019-05-11",
      "has_results": true,
      "last_update_posted_date": "2020-04-22",
      "last_synced_at": "2026-09-12T16:10:05.369Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03440918"
    },
    {
      "nct_id": "NCT04199117",
      "title": "Health Systems Reach Interventions Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking, Cigarette",
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Combination nicotine patch and nicotine mini-lozenge treatment",
          "type": "DRUG"
        },
        {
          "name": "Monetary incentives for initiating treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Automated tailored outreach",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Care management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Wisconsin Tobacco Quit Line referral",
          "type": "OTHER"
        },
        {
          "name": "Primary care provider referral",
          "type": "OTHER"
        },
        {
          "name": "Untailored outreach",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Multiple smoking cessation coaching calls",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 210,
      "start_date": "2020-03-11",
      "completion_date": "2024-10-16",
      "has_results": true,
      "last_update_posted_date": "2025-09-24",
      "last_synced_at": "2026-09-12T16:10:05.369Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04199117"
    },
    {
      "nct_id": "NCT05551325",
      "title": "Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "Sleep Deprivation",
        "Circadian Rhythm Sleep Disorder, Unspecified"
      ],
      "interventions": [
        {
          "name": "Chronobundle - light",
          "type": "OTHER"
        },
        {
          "name": "chronobundle - feeding",
          "type": "OTHER"
        },
        {
          "name": "chronobundle - mobility",
          "type": "OTHER"
        },
        {
          "name": "chronobundle - sleep",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2024-05-13",
      "completion_date": "2029-06-29",
      "has_results": false,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-09-12T16:10:05.369Z",
      "location_count": 2,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05551325"
    },
    {
      "nct_id": "NCT00322010",
      "title": "Early Directed Physical Therapy in the Management of Mechanically Ventilated Patients in a Medical Intensive Care Unit",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mechanically Ventilated Patients"
      ],
      "interventions": [
        {
          "name": "early PT OT",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 104,
      "start_date": "2005-06",
      "completion_date": "2007-10",
      "has_results": false,
      "last_update_posted_date": "2014-03-18",
      "last_synced_at": "2026-09-12T16:10:05.369Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00322010"
    },
    {
      "nct_id": "NCT00519935",
      "title": "Testing MST to Improve Adherence Among Youth With Chronic Poor Metabolic Control",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 1 Diabetes"
      ],
      "interventions": [
        {
          "name": "Multisystemic Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Wayne State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "10 Years to 16 Years"
      },
      "enrollment_count": 127,
      "start_date": "2001-07",
      "completion_date": "2006-03",
      "has_results": false,
      "last_update_posted_date": "2017-06-02",
      "last_synced_at": "2026-09-12T16:10:05.369Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00519935"
    },
    {
      "nct_id": "NCT01951378",
      "title": "Comparison of Nebulizers in ED in Pediatric Asthma Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Asthma"
      ],
      "interventions": [
        {
          "name": "Hudson RCI® nebulizer",
          "type": "DEVICE"
        },
        {
          "name": "NebuTech® HDN® nebulizer",
          "type": "DEVICE"
        },
        {
          "name": "Albuterol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Seton Healthcare Family",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "3 Years to 17 Years"
      },
      "enrollment_count": 40,
      "start_date": "2013-09",
      "completion_date": "2016-07",
      "has_results": true,
      "last_update_posted_date": "2021-04-08",
      "last_synced_at": "2026-09-12T16:10:05.369Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01951378"
    }
  ]
}