{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intercostal+nerve+block",
    "query": {
      "intervention": "Intercostal nerve block"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 48,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intercostal+nerve+block&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-12T18:29:45.999Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03653988",
      "title": "Comparison of Pre-op and Post-op Pectoralis Nerve Block",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Postoperative Pain",
        "Anesthesia",
        "Nerve Block"
      ],
      "interventions": [
        {
          "name": "PEC I/II blocks by anesthesiologist - pre-operative",
          "type": "PROCEDURE"
        },
        {
          "name": "PEC I/II blocks by surgeon - intra-operative",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Melinda Seering",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 80 Years · Female only"
      },
      "enrollment_count": 34,
      "start_date": "2019-03-12",
      "completion_date": "2021-10-31",
      "has_results": true,
      "last_update_posted_date": "2024-08-16",
      "last_synced_at": "2026-09-12T18:29:45.999Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03653988"
    },
    {
      "nct_id": "NCT04198662",
      "title": "Rib Fracture Analgesia Using Cryoanalgesia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Traumatic Rib Fracture(s)"
      ],
      "interventions": [
        {
          "name": "Cryoneurolysis with a Painblocker (Epimed International, Farmers Branch, Texas)",
          "type": "DEVICE"
        },
        {
          "name": "Intercostal nerve block ropivacaine with epinephrine",
          "type": "DRUG"
        },
        {
          "name": "Sham cryoneurolysis with a Painblocker",
          "type": "DEVICE"
        },
        {
          "name": "Placebo intercostal nerve block with normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2020-04-03",
      "completion_date": "2024-08-27",
      "has_results": true,
      "last_update_posted_date": "2024-10-10",
      "last_synced_at": "2026-09-12T18:29:45.999Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04198662"
    },
    {
      "nct_id": "NCT05003765",
      "title": "Are Superficial Parasternal Intercostal Plane (SPIP) Blocks With Bupivacaine and With or Without Adjuvants Helpful for Post-operative Pain After Coronary Artery Bypass Grafting?",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-operative Pain Management"
      ],
      "interventions": [
        {
          "name": "Bupivacaine 0.25% Injectable Solution",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine 0.25% Injectable Solution, Magnesium Sulfate 200 mg",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine 0.25% Injectable Solution, Magnesium Sulfate 200 mg, Buprenorphine 300 mcg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wayne State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 200,
      "start_date": "2020-08-06",
      "completion_date": "2022-05-01",
      "has_results": false,
      "last_update_posted_date": "2021-08-12",
      "last_synced_at": "2026-09-12T18:29:45.999Z",
      "location_count": 1,
      "location_summary": "Pontiac, Michigan",
      "locations": [
        {
          "city": "Pontiac",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05003765"
    },
    {
      "nct_id": "NCT00373633",
      "title": "Extrapleural Intercostal Catheter vs. Thoracic Epidural for Thoracotomy Pain",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "THoracotomy"
      ],
      "interventions": [
        {
          "name": "Thoracic Epidural",
          "type": "PROCEDURE"
        },
        {
          "name": "Extrapleural Intercostal Catheter",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2006-09",
      "completion_date": "2012-01",
      "has_results": false,
      "last_update_posted_date": "2014-08-15",
      "last_synced_at": "2026-09-12T18:29:45.999Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00373633"
    },
    {
      "nct_id": "NCT03708198",
      "title": "Pharmacokinetics of Single-Dose Liposomal Bupivacaine in Surgeon Performed Intercostal Nerve Blocks",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Thoracic"
      ],
      "interventions": [
        {
          "name": "Liposomal Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2018-06-11",
      "completion_date": "2020-08-11",
      "has_results": true,
      "last_update_posted_date": "2022-05-23",
      "last_synced_at": "2026-09-12T18:29:45.999Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03708198"
    },
    {
      "nct_id": "NCT07527039",
      "title": "Pectoral Block in Breast Reduction for Pain Control",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Macromastia (Symptomatic)"
      ],
      "interventions": [
        {
          "name": "Pectoral II Nerve Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Post Operative Pain Relievers",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Carilion Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 80,
      "start_date": "2026-04-01",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-09-12T18:29:45.999Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07527039"
    },
    {
      "nct_id": "NCT01599403",
      "title": "Thoracic Blocks Versus Thoracic Epidural and Patient Controlled Anesthesia in Traumatic Rib Fracture Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Rib Fracture"
      ],
      "interventions": [
        {
          "name": "Paravertebral Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Intercostal Nerve Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Epidural Block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 50,
      "start_date": "2012-04",
      "completion_date": "2017-02-01",
      "has_results": false,
      "last_update_posted_date": "2017-02-13",
      "last_synced_at": "2026-09-12T18:29:45.999Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01599403"
    },
    {
      "nct_id": "NCT06533904",
      "title": "Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Trauma",
        "Rib Fractures",
        "Chest Wall Disorder",
        "Respiratory Insufficiency",
        "Pain, Chest",
        "Rib Trauma",
        "Rib Fracture Multiple",
        "Respiratory Failure",
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Percutaneous Cryoablation of Intercostal Nerves",
          "type": "PROCEDURE"
        },
        {
          "name": "Multi-modal pain regimen",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2026-09",
      "completion_date": "2028-07",
      "has_results": false,
      "last_update_posted_date": "2026-02-09",
      "last_synced_at": "2026-09-12T18:29:45.999Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06533904"
    },
    {
      "nct_id": "NCT00807209",
      "title": "Dose Finding Posterolateral Thoracotomy Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "Low Dose SKY0402",
          "type": "DRUG"
        },
        {
          "name": "High Dose SKY0402",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Fentanyl via PCA",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine via epidural",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pacira Pharmaceuticals, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2008-12",
      "completion_date": "2009-02",
      "has_results": true,
      "last_update_posted_date": "2012-05-15",
      "last_synced_at": "2026-09-12T18:29:45.999Z",
      "location_count": 5,
      "location_summary": "Pasadena, California • Orlando, Florida • Houston, Texas + 1 more",
      "locations": [
        {
          "city": "Pasadena",
          "state": "California"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Tacoma",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00807209"
    },
    {
      "nct_id": "NCT01802411",
      "title": "Intercostal Nerve Block With Liposome Bupivacaine in Subjects Undergoing Posterolateral Thoracotomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Posterolateral Thoracotomy",
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "EXPAREL 266 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pacira Pharmaceuticals, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 191,
      "start_date": "2012-12",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2021-07-12",
      "last_synced_at": "2026-09-12T18:29:45.999Z",
      "location_count": 7,
      "location_summary": "Miami, Florida • Shreveport, Louisiana • Fargo, North Dakota + 4 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        },
        {
          "city": "Fargo",
          "state": "North Dakota"
        },
        {
          "city": "Bellaire",
          "state": "Texas"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01802411"
    }
  ]
}