{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intermediate+nicotine+level+cigarette&page=2",
    "query": {
      "intervention": "Intermediate nicotine level cigarette",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intermediate+nicotine+level+cigarette&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-24T20:05:28.454Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01568905",
      "title": "Palatability of Experimental Cigarettes - Study 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking"
      ],
      "interventions": [
        {
          "name": "Low level nicotine cigarette",
          "type": "OTHER"
        },
        {
          "name": "Intermediate nicotine level cigarette",
          "type": "OTHER"
        },
        {
          "name": "High level nicotine cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 36,
      "start_date": "2011-02",
      "completion_date": "2012-03",
      "has_results": true,
      "last_update_posted_date": "2019-11-01",
      "last_synced_at": "2026-09-24T20:05:28.454Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01568905"
    },
    {
      "nct_id": "NCT03720899",
      "title": "Comparing NicoBloc to Nicotine Lozenges",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Smoking Cessation",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "NicoBloc",
          "type": "DRUG"
        },
        {
          "name": "Nicotine Lozenge",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2019-03-21",
      "completion_date": "2021-03-03",
      "has_results": true,
      "last_update_posted_date": "2025-04-08",
      "last_synced_at": "2026-09-24T20:05:28.454Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03720899"
    },
    {
      "nct_id": "NCT01511614",
      "title": "Nicotine Withdrawal Symptoms and Smoking Relapse",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Transcranial Direct Current Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "sham",
          "type": "DEVICE"
        },
        {
          "name": "Nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Placebo patch",
          "type": "DRUG"
        },
        {
          "name": "Varenicline Pill",
          "type": "DRUG"
        },
        {
          "name": "Placebo pill",
          "type": "DRUG"
        },
        {
          "name": "Motivational Interviewing",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "National Institute on Drug Abuse (NIDA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 112,
      "start_date": "2013-05-20",
      "completion_date": "2020-03-30",
      "has_results": true,
      "last_update_posted_date": "2024-05-31",
      "last_synced_at": "2026-09-24T20:05:28.454Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01511614"
    },
    {
      "nct_id": "NCT05960305",
      "title": "CSD201204 An Actual Use Study of P12 Electronic Nicotine Delivery System Among U.S. Adult Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking, Tobacco"
      ],
      "interventions": [
        {
          "name": "P1213416",
          "type": "OTHER"
        },
        {
          "name": "P1213422",
          "type": "OTHER"
        },
        {
          "name": "P1213716",
          "type": "OTHER"
        },
        {
          "name": "P1213722",
          "type": "OTHER"
        },
        {
          "name": "P1211216",
          "type": "OTHER"
        },
        {
          "name": "P1211222",
          "type": "OTHER"
        },
        {
          "name": "P1213616",
          "type": "OTHER"
        },
        {
          "name": "P1213622",
          "type": "OTHER"
        },
        {
          "name": "P1213816",
          "type": "OTHER"
        },
        {
          "name": "P1213822",
          "type": "OTHER"
        },
        {
          "name": "P1211916",
          "type": "OTHER"
        },
        {
          "name": "P1211922",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RAI Services Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 1845,
      "start_date": "2023-09-15",
      "completion_date": "2024-01-28",
      "has_results": false,
      "last_update_posted_date": "2024-02-23",
      "last_synced_at": "2026-09-24T20:05:28.454Z",
      "location_count": 12,
      "location_summary": "Phoenix, Arizona • Fort Lauderdale, Florida • Orlando, Florida + 9 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05960305"
    },
    {
      "nct_id": "NCT07598136",
      "title": "A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Tobacco"
      ],
      "interventions": [
        {
          "name": "P2613422",
          "type": "OTHER"
        },
        {
          "name": "P2611222",
          "type": "OTHER"
        },
        {
          "name": "P2615522",
          "type": "OTHER"
        },
        {
          "name": "P2615122",
          "type": "OTHER"
        },
        {
          "name": "P2615422",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RAI Services Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 1280,
      "start_date": "2026-05-14",
      "completion_date": "2027-01-21",
      "has_results": false,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-09-24T20:05:28.454Z",
      "location_count": 7,
      "location_summary": "Maitland, Florida • Atlanta, Georgia • St Louis, Missouri + 4 more",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07598136"
    },
    {
      "nct_id": "NCT03651869",
      "title": "Effects of Nicotine in Tobacco Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Smoking, Tobacco",
        "Smoking (Tobacco) Addiction"
      ],
      "interventions": [
        {
          "name": "Cigarette 1",
          "type": "DRUG"
        },
        {
          "name": "Cigarette 2",
          "type": "DRUG"
        },
        {
          "name": "Patch 1",
          "type": "DRUG"
        },
        {
          "name": "Patch 2",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 221,
      "start_date": "2019-02-04",
      "completion_date": "2023-03-23",
      "has_results": false,
      "last_update_posted_date": "2023-07-13",
      "last_synced_at": "2026-09-24T20:05:28.454Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03651869"
    },
    {
      "nct_id": "NCT04429932",
      "title": "A Study to Evaluate Nicotine Uptake and Biomarkers in Adult Smokers Using mybluTM Electronic Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Myblu flavor A_2.4",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor B_2.4",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor C_2.4",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor D_2.4",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor E_1.2",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor F_1.2",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor G_2.4",
          "type": "OTHER"
        },
        {
          "name": "Myblu flavor H_2.4",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Fontem US LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 39,
      "start_date": "2019-12-01",
      "completion_date": "2020-01-31",
      "has_results": true,
      "last_update_posted_date": "2021-06-07",
      "last_synced_at": "2026-09-24T20:05:28.454Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04429932"
    },
    {
      "nct_id": "NCT00714896",
      "title": "Interventions for Smoking Among Persons in Recovery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Stepped-Care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 75,
      "start_date": "2007-04",
      "completion_date": "2009-08",
      "has_results": false,
      "last_update_posted_date": "2013-05-29",
      "last_synced_at": "2026-09-24T20:05:28.454Z",
      "location_count": 1,
      "location_summary": "Walnut Creek, California",
      "locations": [
        {
          "city": "Walnut Creek",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00714896"
    },
    {
      "nct_id": "NCT06372899",
      "title": "Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "E-cigarette Use",
        "Cigarette Smoking",
        "Harm Reduction",
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "E-cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Oral nicotine pouches",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Abramson Cancer Center at Penn Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2024-10-02",
      "completion_date": "2028-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-12",
      "last_synced_at": "2026-09-24T20:05:28.454Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06372899"
    },
    {
      "nct_id": "NCT05473585",
      "title": "Impact of New Standards for Tobacco Products Among Dual E-Cigarette/Combusted Cigarette Users - Project 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Smoking, Cigarette",
        "E-Cig Use",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "very low nicotine content cigarettes",
          "type": "OTHER"
        },
        {
          "name": "normal nicotine content cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Study e-cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2022-10-12",
      "completion_date": "2023-05-09",
      "has_results": false,
      "last_update_posted_date": "2023-07-19",
      "last_synced_at": "2026-09-24T20:05:28.454Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05473585"
    }
  ]
}