{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intervention+2+-+Sham+Treatment&page=41",
    "query": {
      "intervention": "Intervention 2 - Sham Treatment",
      "page": 41
    },
    "page_size": 10
  },
  "pagination": {
    "page": 41,
    "page_size": 10,
    "total_count": 1792,
    "total_pages": 180,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intervention+2+-+Sham+Treatment&page=42&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intervention+2+-+Sham+Treatment&page=40&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-07T14:57:45.656Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05291975",
      "title": "Clinical Efficacy and Human Factors Validation Testing of the Erchonia EVRL for Providing Temporary Relief of Diabetic Peripheral Neuropathy Foot Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neuropathy, Diabetic",
        "Neuropathy;Peripheral",
        "Neuropathy, Painful"
      ],
      "interventions": [
        {
          "name": "Erchonia® EVRL™",
          "type": "DEVICE"
        },
        {
          "name": "Placebo Laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Erchonia Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 64,
      "start_date": "2022-02-17",
      "completion_date": "2024-12-12",
      "has_results": true,
      "last_update_posted_date": "2025-08-13",
      "last_synced_at": "2026-11-07T14:57:45.656Z",
      "location_count": 4,
      "location_summary": "Phoenix, Arizona • West Covina, California • Dunedin, Florida + 1 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "West Covina",
          "state": "California"
        },
        {
          "city": "Dunedin",
          "state": "Florida"
        },
        {
          "city": "Miramar",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05291975"
    },
    {
      "nct_id": "NCT07015528",
      "title": "Assessment of Drug Liking In Peri-procedural Clinical Settings",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Drug Liking"
      ],
      "interventions": [
        {
          "name": "Droperidol",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 130,
      "start_date": "2025-09-30",
      "completion_date": "2027-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-30",
      "last_synced_at": "2026-11-07T14:57:45.656Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07015528"
    },
    {
      "nct_id": "NCT07403604",
      "title": "Effect of Insulin Lowering on Lipogenesis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hyperinsulinemia",
        "Insulin Resistance",
        "Non-Alcoholic Fatty Liver Disease",
        "Prediabetic State",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Diazoxide Oral Suspension, 2 mg per kg per dose",
          "type": "DRUG"
        },
        {
          "name": "Deuterated water (2H2O/D2O), 70%",
          "type": "DRUG"
        },
        {
          "name": "Insulin Suppression Test (IST)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 25,
      "start_date": "2026-07-01",
      "completion_date": "2029-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-06",
      "last_synced_at": "2026-11-07T14:57:45.656Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07403604"
    },
    {
      "nct_id": "NCT00580606",
      "title": "A Randomized, Double-Blind Placebo-Controlled Peanut Sublingual Immunotherapy Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Food Hypersensitivity",
        "Hypersensitivity",
        "Immediate Hypersensitivity",
        "Peanut Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "Glycerinated peanut allergenic extract",
          "type": "DRUG"
        },
        {
          "name": "Placebo for peanut extract (glycerin)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "12 Years to 40 Years"
      },
      "enrollment_count": 40,
      "start_date": "2007-12",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2019-08-21",
      "last_synced_at": "2026-11-07T14:57:45.656Z",
      "location_count": 5,
      "location_summary": "Little Rock, Arkansas • Denver, Colorado • Baltimore, Maryland + 2 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00580606"
    },
    {
      "nct_id": "NCT00065806",
      "title": "Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Lupus Erythematosus, Systemic"
      ],
      "interventions": [
        {
          "name": "Atorvastatin",
          "type": "DRUG"
        },
        {
          "name": "Placebo atorvastatin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Laura Schanberg",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "10 Years to 21 Years"
      },
      "enrollment_count": 221,
      "start_date": "2003-09",
      "completion_date": "2009-12",
      "has_results": true,
      "last_update_posted_date": "2013-08-15",
      "last_synced_at": "2026-11-07T14:57:45.656Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00065806"
    },
    {
      "nct_id": "NCT00592306",
      "title": "Intraoperative Versus Postoperative Thymoglobulin in Lung Transplantation",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Lung Transplant"
      ],
      "interventions": [
        {
          "name": "thymoglobulin (intraoperative)",
          "type": "DRUG"
        },
        {
          "name": "thymoglobulin (postoperative)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2006-01",
      "completion_date": "2010-09",
      "has_results": false,
      "last_update_posted_date": "2020-09-10",
      "last_synced_at": "2026-11-07T14:57:45.656Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00592306"
    },
    {
      "nct_id": "NCT07387315",
      "title": "A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Overactive Bladder",
        "Neurogenic Bladder",
        "Urge Incontinence",
        "Pain",
        "Urinary Incontinence",
        "Urinary Bladder, Overactive",
        "Urinary Bladder, Neurogenic",
        "Urinary Bladder Neurogenesis",
        "Urinary Incontinence, Urge",
        "Pelvic Floor Disorders"
      ],
      "interventions": [
        {
          "name": "Pro-Nox Nitrous Oxide/Oxygen Delivery System",
          "type": "DRUG"
        },
        {
          "name": "Standard Care for Bladder Botox Injection",
          "type": "DRUG"
        },
        {
          "name": "Sham Mask",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "TriHealth Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 96,
      "start_date": "2026-02",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-11-07T14:57:45.656Z",
      "location_count": 2,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07387315"
    },
    {
      "nct_id": "NCT07195552",
      "title": "Clinical Trial: Rapid Immune Modulating Effects",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Immune Surveillance"
      ],
      "interventions": [
        {
          "name": "Agaricus blazei",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Reishi",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Turkey Tail",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Natural Immune Systems Inc",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 12,
      "start_date": "2024-07-01",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2025-09-26",
      "last_synced_at": "2026-11-07T14:57:45.656Z",
      "location_count": 1,
      "location_summary": "Klamath Falls, Oregon",
      "locations": [
        {
          "city": "Klamath Falls",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07195552"
    },
    {
      "nct_id": "NCT05717153",
      "title": "Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Diffuse Glioma",
        "Malignant Glioma"
      ],
      "interventions": [
        {
          "name": "Biospecimen Collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Computed Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Eflornithine",
          "type": "DRUG"
        },
        {
          "name": "Magnetic Resonance Imaging",
          "type": "PROCEDURE"
        },
        {
          "name": "Polyamine Transport Inhibitor AMXT-1501 Dicaprate",
          "type": "DRUG"
        },
        {
          "name": "Resection",
          "type": "PROCEDURE"
        },
        {
          "name": "Microdialysis",
          "type": "DEVICE"
        },
        {
          "name": "Placement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2023-09-15",
      "completion_date": "2028-02-29",
      "has_results": false,
      "last_update_posted_date": "2026-11-04",
      "last_synced_at": "2026-11-07T14:57:45.656Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05717153"
    },
    {
      "nct_id": "NCT00475007",
      "title": "Clinical Trial to Evaluate the Safety and Effectiveness of the IBV® Valve System for the Treatment of Severe Emphysema",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Emphysema",
        "COPD"
      ],
      "interventions": [
        {
          "name": "IBV® Valve System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Olympus Corporation of the Americas",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "40 Years to 74 Years"
      },
      "enrollment_count": 277,
      "start_date": "2007-09",
      "completion_date": "2017-08",
      "has_results": false,
      "last_update_posted_date": "2018-04-17",
      "last_synced_at": "2026-11-07T14:57:45.656Z",
      "location_count": 34,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Mission Viejo, California + 29 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Mission Viejo",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00475007"
    }
  ]
}