{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intervention+4+%28sham%29",
    "query": {
      "intervention": "Intervention 4 (sham)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 297,
    "total_pages": 30,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intervention+4+%28sham%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-24T01:29:28.681Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04100486",
      "title": "Non-Invasive Bioelectronic Analytics",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Autonomic Dysfunction",
        "Autonomic Imbalance",
        "Autonomic Nervous System Diseases",
        "Vagus Nerve Autonomic Disorder"
      ],
      "interventions": [
        {
          "name": "Standing-Squatting-Standing Test",
          "type": "OTHER"
        },
        {
          "name": "Deep Breathing Test",
          "type": "OTHER"
        },
        {
          "name": "Cold Pressor Test",
          "type": "OTHER"
        },
        {
          "name": "Cold Face Test",
          "type": "OTHER"
        },
        {
          "name": "Valsalva Maneuver",
          "type": "OTHER"
        },
        {
          "name": "Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 48,
      "start_date": "2019-08-29",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-09-24T01:29:28.681Z",
      "location_count": 1,
      "location_summary": "Manhasset, New York",
      "locations": [
        {
          "city": "Manhasset",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04100486"
    },
    {
      "nct_id": "NCT01214070",
      "title": "Functional Vision in TBI",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Brain Injuries",
        "Visually Impaired Persons"
      ],
      "interventions": [
        {
          "name": "Vision Restoration Therapy",
          "type": "OTHER"
        },
        {
          "name": "NVT Eye Scanning Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Eccentric Viewing Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "20 Years to 79 Years"
      },
      "enrollment_count": 110,
      "start_date": "2012-06-01",
      "completion_date": "2013-11-21",
      "has_results": false,
      "last_update_posted_date": "2017-06-16",
      "last_synced_at": "2026-09-24T01:29:28.681Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01214070"
    },
    {
      "nct_id": "NCT03244475",
      "title": "Transcranial Electrical Stimulation for mTBI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Traumatic Brain Injury (mTBI)",
        "Post-traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "TES",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 66,
      "start_date": "2017-02-01",
      "completion_date": "2022-09-30",
      "has_results": true,
      "last_update_posted_date": "2024-01-18",
      "last_synced_at": "2026-09-24T01:29:28.681Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03244475"
    },
    {
      "nct_id": "NCT05866471",
      "title": "The ENHANCE Study: taVNS and Psilocybin",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy",
        "Psychedelic Experiences",
        "Vagus Nerve Stimulation"
      ],
      "interventions": [
        {
          "name": "Psilocybin",
          "type": "DRUG"
        },
        {
          "name": "Transcutaneous auricular Vagus Nerve Stimulation (taVNS)",
          "type": "DEVICE"
        },
        {
          "name": "Psychosocial Support Alone",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham taVNS",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 108,
      "start_date": "2025-01-27",
      "completion_date": "2028-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-29",
      "last_synced_at": "2026-09-24T01:29:28.681Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05866471"
    },
    {
      "nct_id": "NCT05642312",
      "title": "A Study to Investigate Vamikibart in Participants With Uveitic Macular Edema",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Uveitic Macular Edema"
      ],
      "interventions": [
        {
          "name": "Vamikibart",
          "type": "DRUG"
        },
        {
          "name": "Sham",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Hoffmann-La Roche",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 245,
      "start_date": "2023-01-09",
      "completion_date": "2025-07-09",
      "has_results": false,
      "last_update_posted_date": "2025-11-21",
      "last_synced_at": "2026-09-24T01:29:28.681Z",
      "location_count": 16,
      "location_summary": "Los Angeles, California • Lakewood, Colorado • St. Petersburg, Florida + 13 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Lakewood",
          "state": "Colorado"
        },
        {
          "city": "St. Petersburg",
          "state": "Florida"
        },
        {
          "city": "Hagerstown",
          "state": "Maryland"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05642312"
    },
    {
      "nct_id": "NCT06610617",
      "title": "Neuromodulation of Central Sensory Integration to Improve Postural Control",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Survivorship",
        "Quality of Life",
        "Cognitive Deficits, Mild"
      ],
      "interventions": [
        {
          "name": "transcranial direct current stimulation (tDCS)",
          "type": "DEVICE"
        },
        {
          "name": "Sham tDCS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "FEMALE",
        "summary": "50 Years to 85 Years · Female only"
      },
      "enrollment_count": 48,
      "start_date": "2024-10-14",
      "completion_date": "2025-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-12",
      "last_synced_at": "2026-09-24T01:29:28.681Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06610617"
    },
    {
      "nct_id": "NCT04964089",
      "title": "A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Wet Age-related Macular Degeneration"
      ],
      "interventions": [
        {
          "name": "KSI-301",
          "type": "DRUG"
        },
        {
          "name": "Aflibercept",
          "type": "DRUG"
        },
        {
          "name": "Sham Procedure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Kodiak Sciences Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 557,
      "start_date": "2021-06-23",
      "completion_date": "2023-04-06",
      "has_results": true,
      "last_update_posted_date": "2024-07-03",
      "last_synced_at": "2026-09-24T01:29:28.681Z",
      "location_count": 65,
      "location_summary": "Phoenix, Arizona • Springdale, Arkansas • Bakersfield, California + 60 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Springdale",
          "state": "Arkansas"
        },
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Fullerton",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04964089"
    },
    {
      "nct_id": "NCT01653691",
      "title": "Laser Therapy for Treating Hypertrophic Burn Scars in Children",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Burn Scars"
      ],
      "interventions": [
        {
          "name": "Pulse-Dye Laser",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "9 Years to 21 Years"
      },
      "enrollment_count": 80,
      "start_date": "2012-05",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2012-07-31",
      "last_synced_at": "2026-09-24T01:29:28.681Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01653691"
    },
    {
      "nct_id": "NCT05049460",
      "title": "Adjunctive Transcranial Stimulation to Reduce Impulsivity in Opiate Use Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid-use Disorder",
        "Tobacco Use Disorder"
      ],
      "interventions": [
        {
          "name": "Theta Burst Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Sham TMS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Gopalkumar Rakesh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 23,
      "start_date": "2021-09-15",
      "completion_date": "2024-07-31",
      "has_results": true,
      "last_update_posted_date": "2025-10-22",
      "last_synced_at": "2026-09-24T01:29:28.681Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05049460"
    },
    {
      "nct_id": "NCT06399900",
      "title": "ENhancing Exercise With LIGHT to Improve Functioning in PAD",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peripheral Artery Disease",
        "Peripheral Vascular Disease",
        "Aging",
        "Walking, Difficulty"
      ],
      "interventions": [
        {
          "name": "Far red light therapy",
          "type": "DEVICE"
        },
        {
          "name": "Sham light therapy",
          "type": "DEVICE"
        },
        {
          "name": "Home-based walking exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2024-08-12",
      "completion_date": "2027-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-09-24T01:29:28.681Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06399900"
    }
  ]
}