{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intervention+letter",
    "query": {
      "intervention": "Intervention letter"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 259,
    "total_pages": 26,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intervention+letter&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T21:02:36.009Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00246051",
      "title": "Comprehensive Police Fatigue Management Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Disorders",
        "Sleep Apnea, Obstructive",
        "Restless Legs Syndrome",
        "Sleep Disorders, Circadian Rhythm",
        "Sleep Initiation and Maintenance Disorders"
      ],
      "interventions": [
        {
          "name": "Sleep Hygiene Education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Expert-Led Sleep Disorders Screening and Treatment",
          "type": "OTHER"
        },
        {
          "name": "Online Sleep Disorders Screening",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 683,
      "start_date": "2005-11",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2013-08-15",
      "last_synced_at": "2026-09-06T21:02:36.009Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00246051"
    },
    {
      "nct_id": "NCT00323258",
      "title": "Study of an Intervention to Improve Use of Life-saving Medications for Heart Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Disease"
      ],
      "interventions": [
        {
          "name": "oral education & written tips for remembering medications",
          "type": "BEHAVIORAL"
        },
        {
          "name": "pill box",
          "type": "DEVICE"
        },
        {
          "name": "pocket medication card",
          "type": "DEVICE"
        },
        {
          "name": "sharing information with community pharmacist",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Medication use evaluations by community pharmacist",
          "type": "BEHAVIORAL"
        },
        {
          "name": "informing physician if patient has stopped a medication",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Routine discharge counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Letter to physician/discharge summary",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 143,
      "start_date": "2006-06",
      "completion_date": "2011-03",
      "has_results": true,
      "last_update_posted_date": "2013-01-18",
      "last_synced_at": "2026-09-06T21:02:36.009Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00323258"
    },
    {
      "nct_id": "NCT00697047",
      "title": "Systems of Support (SOS) to Increase Colon Cancer Screening and Follow-up",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colorectal Cancer"
      ],
      "interventions": [
        {
          "name": "Automated Mailing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Automated Mailing Plus Assisted",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Auto Plus Assisted Plus Navigation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "73 Years",
        "sex": "ALL",
        "summary": "50 Years to 73 Years"
      },
      "enrollment_count": 4653,
      "start_date": "2008-07",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-11-03",
      "last_synced_at": "2026-09-06T21:02:36.009Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00697047"
    },
    {
      "nct_id": "NCT04574518",
      "title": "Teachable Moment to Opt-out of Tobacco: Interactive Voice Response Quit Line for Veteran Active Smokers With Lung Nodules",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Solitary Pulmonary Nodule",
        "Multiple Pulmonary Nodules",
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "TeaM OUT Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Usual Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 223,
      "start_date": "2022-08-12",
      "completion_date": "2026-10-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-04",
      "last_synced_at": "2026-09-06T21:02:36.009Z",
      "location_count": 3,
      "location_summary": "Minneapolis, Minnesota • Portland, Oregon • Charleston, South Carolina",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04574518"
    },
    {
      "nct_id": "NCT00689013",
      "title": "The Effect of Pharmacist Intervention on the Use of Zostavax in a Community Pharmacy Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Herpes Zoster"
      ],
      "interventions": [
        {
          "name": "Personalized letter",
          "type": "OTHER"
        },
        {
          "name": "Flyer advertisement",
          "type": "OTHER"
        },
        {
          "name": "Newspaper press release",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 205,
      "start_date": "2008-02",
      "completion_date": "2008-03",
      "has_results": false,
      "last_update_posted_date": "2009-04-23",
      "last_synced_at": "2026-09-06T21:02:36.009Z",
      "location_count": 3,
      "location_summary": "Johnson City, Tennessee • Manchester, Tennessee • Murfreesboro, Tennessee",
      "locations": [
        {
          "city": "Johnson City",
          "state": "Tennessee"
        },
        {
          "city": "Manchester",
          "state": "Tennessee"
        },
        {
          "city": "Murfreesboro",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00689013"
    },
    {
      "nct_id": "NCT02395120",
      "title": "Family Access to Dentist Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Standard letter",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Intervention letter",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Reduced intervention letter",
          "type": "BEHAVIORAL"
        },
        {
          "name": "DIG",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Reduced DIG",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "5 Years to 10 Years"
      },
      "enrollment_count": 1305,
      "start_date": "2015-08",
      "completion_date": "2017-05",
      "has_results": true,
      "last_update_posted_date": "2022-06-16",
      "last_synced_at": "2026-09-06T21:02:36.009Z",
      "location_count": 2,
      "location_summary": "Cleveland, Ohio • Seattle, Washington",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02395120"
    },
    {
      "nct_id": "NCT02004145",
      "title": "Trial of a Positive Psychology Intervention in Major Depressive Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Positive Psychology",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Condition",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2013-10",
      "completion_date": "2015-09",
      "has_results": false,
      "last_update_posted_date": "2016-04-19",
      "last_synced_at": "2026-09-06T21:02:36.009Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02004145"
    },
    {
      "nct_id": "NCT02249533",
      "title": "Evaluation of Spot Light: A Concussion Injury Management App for Youth Sports",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "TBI"
      ],
      "interventions": [
        {
          "name": "Spot Light Concussion App",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Lara McKenzie",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "10 Years to 19 Years"
      },
      "enrollment_count": 175,
      "start_date": "2013-12",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2017-02-01",
      "last_synced_at": "2026-09-06T21:02:36.009Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02249533"
    },
    {
      "nct_id": "NCT01323309",
      "title": "Trial of Individual Psychosocial Interventions for Cancer Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Advanced Solid Tumor Diseases"
      ],
      "interventions": [
        {
          "name": "Individual Meaning-Centered Psychotherapy (IMCP)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "standard Individual Supportive Psychotherapy (ISP)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "enhanced usual care (EUC)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 346,
      "start_date": "2011-03-22",
      "completion_date": "2023-02-22",
      "has_results": true,
      "last_update_posted_date": "2024-07-01",
      "last_synced_at": "2026-09-06T21:02:36.009Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01323309"
    },
    {
      "nct_id": "NCT05676099",
      "title": "TSC Biosample Repository and Natural History Database",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tuberous Sclerosis",
        "Lymphangioleiomyomatosis"
      ],
      "interventions": [
        {
          "name": "Phlebotomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Buccal (cheek) swab",
          "type": "PROCEDURE"
        },
        {
          "name": "Genetic Testing",
          "type": "GENETIC"
        },
        {
          "name": "Tissue donation after routine clinical procedure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "GENETIC",
        "OTHER"
      ],
      "sponsor": "National Tuberous Sclerosis Association",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 5000,
      "start_date": "2016-01",
      "completion_date": "2050-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-24",
      "last_synced_at": "2026-09-06T21:02:36.009Z",
      "location_count": 24,
      "location_summary": "Birmingham, Alabama • Loma Linda, California • Los Angeles, California + 19 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05676099"
    }
  ]
}