{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intervention+letter&page=2",
    "query": {
      "intervention": "Intervention letter",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intervention+letter&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-28T18:55:15.294Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01141114",
      "title": "Study of Patient Navigation to Promote Colon Cancer Screening",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colorectal Cancer Screening"
      ],
      "interventions": [
        {
          "name": "Patient navigation",
          "type": "OTHER"
        },
        {
          "name": "Usual care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cambridge Health Alliance",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "52 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "52 Years to 75 Years"
      },
      "enrollment_count": 465,
      "start_date": "2008-09",
      "completion_date": "2010-03",
      "has_results": false,
      "last_update_posted_date": "2017-04-18",
      "last_synced_at": "2026-09-28T18:55:15.294Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01141114"
    },
    {
      "nct_id": "NCT02243774",
      "title": "Mail Outreach To Increase Vaccination Acceptance Through Engagement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Influenza, Human",
        "Influenza",
        "Human Flu"
      ],
      "interventions": [
        {
          "name": "Core letter signed by Surgeon General",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Core letter signed by the Director of the National Vaccine Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Core letter signed by Surgeon General + implementation prompt",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Core letter signed by SG + enhanced implementation prompt",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "66 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "66 Years and older"
      },
      "enrollment_count": 228000,
      "start_date": "2014-09",
      "completion_date": "2015-09",
      "has_results": false,
      "last_update_posted_date": "2017-07-12",
      "last_synced_at": "2026-09-28T18:55:15.294Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02243774"
    },
    {
      "nct_id": "NCT02864940",
      "title": "Memory Training in Aneurysmal Subarachnoid Hemorrhage Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ruptured Aneurysm",
        "Memory Deficits",
        "Subarachnoid Hemorrhage"
      ],
      "interventions": [
        {
          "name": "Lumosity",
          "type": "DEVICE"
        },
        {
          "name": "Crossword puzzle",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2016-06",
      "completion_date": "2018-08-28",
      "has_results": true,
      "last_update_posted_date": "2023-04-10",
      "last_synced_at": "2026-09-28T18:55:15.294Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02864940"
    },
    {
      "nct_id": "NCT04568824",
      "title": "Neurocognitive Factors in EdTech Intervention Response",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Reading Disability"
      ],
      "interventions": [
        {
          "name": "GraphoLearn reading intervention",
          "type": "OTHER"
        },
        {
          "name": "Vektor math control intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Connecticut",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "6 Years to 10 Years"
      },
      "enrollment_count": 450,
      "start_date": "2020-11-15",
      "completion_date": "2026-08-01",
      "has_results": false,
      "last_update_posted_date": "2025-09-02",
      "last_synced_at": "2026-09-28T18:55:15.294Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04568824"
    },
    {
      "nct_id": "NCT03028961",
      "title": "Stanford Letter or Traditional Advance Directive in Advance Care Planning in Patients Undergoing Bone Marrow Transplant",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Advance Directives",
        "Bone Marrow Transplant"
      ],
      "interventions": [
        {
          "name": "Stanford Letter",
          "type": "OTHER"
        },
        {
          "name": "Interview",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "CA Advance Health Care Directive Form",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 126,
      "start_date": "2017-03-03",
      "completion_date": "2021-07-27",
      "has_results": false,
      "last_update_posted_date": "2022-06-14",
      "last_synced_at": "2026-09-28T18:55:15.294Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03028961"
    },
    {
      "nct_id": "NCT07678554",
      "title": "Overvaluation of Weight and Shape Intervention vs The Body Project",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Body Image",
        "Mental Health Outcomes",
        "Eating Disorders",
        "Body Dysmorphic Disorders",
        "Self-esteem"
      ],
      "interventions": [
        {
          "name": "Priorities",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Body Project",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "22 Years",
        "sex": "FEMALE",
        "summary": "14 Years to 22 Years · Female only"
      },
      "enrollment_count": 90,
      "start_date": "2026-07-01",
      "completion_date": "2027-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-07",
      "last_synced_at": "2026-09-28T18:55:15.294Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07678554"
    },
    {
      "nct_id": "NCT01582841",
      "title": "Integrating Genetic Testing for Lynch Syndrome in a Managed Care Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colon Cancer",
        "Lynch Syndrome"
      ],
      "interventions": [
        {
          "name": "MSI screening test",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 247,
      "start_date": "2012-02",
      "completion_date": "2016-07",
      "has_results": false,
      "last_update_posted_date": "2016-08-31",
      "last_synced_at": "2026-09-28T18:55:15.294Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01582841"
    },
    {
      "nct_id": "NCT06629272",
      "title": "Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypothyroidism"
      ],
      "interventions": [
        {
          "name": "D-THIO (Deprescribing Thyroid Hormone In Older Adults)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced usual care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 900,
      "start_date": "2024-12-02",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-04",
      "last_synced_at": "2026-09-28T18:55:15.294Z",
      "location_count": 3,
      "location_summary": "San Francisco, California • Ann Arbor, Michigan • Detroit, Michigan",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06629272"
    },
    {
      "nct_id": "NCT01568151",
      "title": "Testing Interventions to Motivate and Educate",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colorectal Cancer"
      ],
      "interventions": [
        {
          "name": "Clinic-directed intervention program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Individual Patient-Directed Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio State University Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 551,
      "start_date": "2009-04",
      "completion_date": "2013-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-04-28",
      "last_synced_at": "2026-09-28T18:55:15.294Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01568151"
    },
    {
      "nct_id": "NCT04471194",
      "title": "Multilevel Intervention Based on Colorectal Cancer (CRC) and Cervical Cancer Self-screening in Rural, Segregated Areas",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colorectal Cancer Screening",
        "Cervical Cancer Screening"
      ],
      "interventions": [
        {
          "name": "Self-sampling HPV test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Fecal occult blood test",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "50 Years to 65 Years · Female only"
      },
      "enrollment_count": 48,
      "start_date": "2021-02-18",
      "completion_date": "2022-03-01",
      "has_results": true,
      "last_update_posted_date": "2022-12-13",
      "last_synced_at": "2026-09-28T18:55:15.294Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04471194"
    }
  ]
}