{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intravenous+fluid+bolus",
    "query": {
      "intervention": "Intravenous fluid bolus"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 62,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intravenous+fluid+bolus&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-23T01:24:01.058Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00787176",
      "title": "The Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pregnancy",
        "Labor Pain"
      ],
      "interventions": [
        {
          "name": "Group A Intravenous bolus of 1000 ml lactated ringers solution",
          "type": "DRUG"
        },
        {
          "name": "Group B Intravenous bolus bolus 1000 ml lactated ringers solution oxytocin decrease to 1/2 current rate",
          "type": "DRUG"
        },
        {
          "name": "Group C 125 mL/hr of lactated ringers",
          "type": "DRUG"
        },
        {
          "name": "Group D 125 mL/hr lactated ringers oxytocin decreased to 1/2 current rate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 251,
      "start_date": "2007-09",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2022-01-13",
      "last_synced_at": "2026-09-23T01:24:01.058Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00787176"
    },
    {
      "nct_id": "NCT01343758",
      "title": "Study Investigating the Use of Intravenous Fluids With Dextrose for Dehydrated Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gastroenteritis",
        "Dehydration"
      ],
      "interventions": [
        {
          "name": "5% dextrose in normal saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "6 Months to 6 Years"
      },
      "enrollment_count": 188,
      "start_date": "2007-01",
      "completion_date": "2011-07",
      "has_results": false,
      "last_update_posted_date": "2012-02-24",
      "last_synced_at": "2026-09-23T01:24:01.058Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01343758"
    },
    {
      "nct_id": "NCT02565485",
      "title": "Pulse Pressure and Post-epidural Fetal Heart Rate Changes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fetus or Neonate Affected by Maternal Epidural Anesthesia During Labor and Delivery"
      ],
      "interventions": [
        {
          "name": "Lactated Ringer's",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "MetroHealth Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 276,
      "start_date": "2015-09-01",
      "completion_date": "2016-11-01",
      "has_results": true,
      "last_update_posted_date": "2018-07-09",
      "last_synced_at": "2026-09-23T01:24:01.058Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02565485"
    },
    {
      "nct_id": "NCT04177225",
      "title": "Effect of Diastolic Dysfunction on Dynamic Cardiac Monitors",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stroke Volume Variation",
        "Diastolic Dysfunction"
      ],
      "interventions": [
        {
          "name": "Trans thoracic Ultrasound Examination",
          "type": "PROCEDURE"
        },
        {
          "name": "Intravenous fluid administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2019-02-07",
      "completion_date": "2021-02-01",
      "has_results": false,
      "last_update_posted_date": "2021-02-12",
      "last_synced_at": "2026-09-23T01:24:01.058Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04177225"
    },
    {
      "nct_id": "NCT01758549",
      "title": "Randomized Trial of Aggressive Fluid Hydration to Prevent Post ERCP Pancreatitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pancreatitis"
      ],
      "interventions": [
        {
          "name": "Aggressive Intravenous Hydration Group",
          "type": "OTHER"
        },
        {
          "name": "Standard Fluids Arm",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 62,
      "start_date": "2012-07",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2014-07-01",
      "last_synced_at": "2026-09-23T01:24:01.058Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01758549"
    },
    {
      "nct_id": "NCT01195883",
      "title": "Effect of Goal-directed Crystalloid Versus Colloid Administration on Major Postoperative Morbidity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Complications"
      ],
      "interventions": [
        {
          "name": "Crystalloid",
          "type": "DRUG"
        },
        {
          "name": "Colloid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 1102,
      "start_date": "2010-11",
      "completion_date": "2017-10-20",
      "has_results": true,
      "last_update_posted_date": "2018-10-30",
      "last_synced_at": "2026-09-23T01:24:01.058Z",
      "location_count": 2,
      "location_summary": "Cleveland, Ohio • Mayfield Heights, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Mayfield Heights",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01195883"
    },
    {
      "nct_id": "NCT01176565",
      "title": "Antihypertensive Treatment of Acute Cerebral Hemorrhage-II",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Intracerebral Hemorrhage"
      ],
      "interventions": [
        {
          "name": "Intravenous nicardipine hydrochloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2011-05-15",
      "completion_date": "2016-03-08",
      "has_results": true,
      "last_update_posted_date": "2017-04-25",
      "last_synced_at": "2026-09-23T01:24:01.058Z",
      "location_count": 116,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 87 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Tuscon",
          "state": "Arizona"
        },
        {
          "city": "Tuscon",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01176565"
    },
    {
      "nct_id": "NCT04110080",
      "title": "Enhanced Recovery After Surgery in Kidney Transplant Donors",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Use",
        "Kidney Diseases",
        "Pain, Postoperative",
        "Postoperative Complications",
        "Postoperative Nausea and Vomiting"
      ],
      "interventions": [
        {
          "name": "multimodal pain management",
          "type": "PROCEDURE"
        },
        {
          "name": "goal directed fluid management",
          "type": "OTHER"
        },
        {
          "name": "preoperative carbohydrate loading",
          "type": "OTHER"
        },
        {
          "name": "Donor nephrectomy",
          "type": "PROCEDURE"
        },
        {
          "name": "regional anesthesia",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 42,
      "start_date": "2019-09-12",
      "completion_date": "2023-06-12",
      "has_results": false,
      "last_update_posted_date": "2023-04-18",
      "last_synced_at": "2026-09-23T01:24:01.058Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04110080"
    },
    {
      "nct_id": "NCT06418022",
      "title": "Evaluating Fluid Responsiveness in ICU Patients Using VTI and Trendelenburg Positioning",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shock",
        "Fluid Overload",
        "Cardiac Output, Low"
      ],
      "interventions": [
        {
          "name": "Trendelenburg positioning VTI",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Lenox Hill Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2024-04-01",
      "completion_date": "2025-08-01",
      "has_results": false,
      "last_update_posted_date": "2024-05-16",
      "last_synced_at": "2026-09-23T01:24:01.058Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06418022"
    },
    {
      "nct_id": "NCT05283850",
      "title": "Surviving PEA in Roanoke (SPEAR) Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Cardiac Arrest",
        "Pulseless Electrical Activity"
      ],
      "interventions": [
        {
          "name": "High Calcium, Low Sodium (HCLS) Crystalloid Therapy",
          "type": "DRUG"
        },
        {
          "name": "High Calcium, High Sodium (HCHS) Crystalloid Therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Carol Bernier",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 342,
      "start_date": "2022-02-16",
      "completion_date": "2027-02",
      "has_results": false,
      "last_update_posted_date": "2022-03-17",
      "last_synced_at": "2026-09-23T01:24:01.058Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05283850"
    }
  ]
}