{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intravenous+lactate+infusion",
    "query": {
      "intervention": "Intravenous lactate infusion"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Intravenous+lactate+infusion&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-21T18:23:06.894Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02951130",
      "title": "Milrinone in Congenital Diaphragmatic Hernia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Congenital Diaphragmatic Hernia",
        "Persistent Pulmonary Hypertension of the Newborn",
        "Hypoxemic Respiratory Failure",
        "Pulmonary Hypoplasia"
      ],
      "interventions": [
        {
          "name": "Milrinone",
          "type": "DRUG"
        },
        {
          "name": "Placebo (5% Dextrose)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Neonatal Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Hours",
        "maximum_age": "168 Hours",
        "sex": "ALL",
        "summary": "0 Hours to 168 Hours"
      },
      "enrollment_count": 66,
      "start_date": "2017-10-24",
      "completion_date": "2025-05-19",
      "has_results": true,
      "last_update_posted_date": "2025-11-06",
      "last_synced_at": "2026-09-21T18:23:06.894Z",
      "location_count": 19,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • Atlanta, Georgia + 15 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02951130"
    },
    {
      "nct_id": "NCT04181606",
      "title": "Age Comparisons of Exercising Muscle O2 Supply in Healthy Adults: Effects of Esmolol Infusion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Aging"
      ],
      "interventions": [
        {
          "name": "Esmolol infusion",
          "type": "DRUG"
        },
        {
          "name": "Saline infusion",
          "type": "DRUG"
        },
        {
          "name": "Pre exercise baseline",
          "type": "OTHER"
        },
        {
          "name": "Isometric handgrip exercise",
          "type": "OTHER"
        },
        {
          "name": "Semi-recumbent cycling",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "David N. Proctor, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2022-02-02",
      "completion_date": "2023-04-25",
      "has_results": true,
      "last_update_posted_date": "2025-05-13",
      "last_synced_at": "2026-09-21T18:23:06.894Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04181606"
    },
    {
      "nct_id": "NCT06825143",
      "title": "Therapeutic Strategies to Reduce Endothelial Ischemia-reperfusion Injury",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Metabolic Syndrome",
        "Vascular Injury",
        "Ischemic Preconditioning",
        "Endothelial Function (reactive Hyperemia)",
        "Endothelial Dysfunction"
      ],
      "interventions": [
        {
          "name": "Ischemic preconditioning",
          "type": "PROCEDURE"
        },
        {
          "name": "Intravenous lactate infusion",
          "type": "DRUG"
        },
        {
          "name": "No ischemic preconditioning (control)",
          "type": "PROCEDURE"
        },
        {
          "name": "Normal Saline Infusion (Placebo)",
          "type": "DRUG"
        },
        {
          "name": "Ischemic preconditioning and intravenous lactate",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Gary Van Guilder",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 68,
      "start_date": "2026-10-01",
      "completion_date": "2030-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-02-13",
      "last_synced_at": "2026-09-21T18:23:06.894Z",
      "location_count": 1,
      "location_summary": "Gunnison, Colorado",
      "locations": [
        {
          "city": "Gunnison",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06825143"
    },
    {
      "nct_id": "NCT05219110",
      "title": "Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection",
        "Hemolytic-Uremic Syndrome"
      ],
      "interventions": [
        {
          "name": "Infusion of 200% maintenance fluids as balanced crystalloid IV solution",
          "type": "OTHER"
        },
        {
          "name": "Oral fluids; infusion of up to 110% maintenance fluids as balanced crystalloid IV solution",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Calgary",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "9 Months",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "9 Months to 21 Years"
      },
      "enrollment_count": 1040,
      "start_date": "2022-09-29",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-09-21T18:23:06.894Z",
      "location_count": 22,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • La Jolla, California + 19 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05219110"
    },
    {
      "nct_id": "NCT05355974",
      "title": "Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Failure",
        "Hypotension and Shock",
        "Hypotension on Induction",
        "Intubation Complication",
        "Anesthesia Intubation Complication"
      ],
      "interventions": [
        {
          "name": "Norepinephrine",
          "type": "DRUG"
        },
        {
          "name": "Lactated Ringers, Intravenous",
          "type": "DRUG"
        },
        {
          "name": "normal saline",
          "type": "DRUG"
        },
        {
          "name": "Plasma-lyte",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wright State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 42,
      "start_date": "2022-08-09",
      "completion_date": "2024-07-10",
      "has_results": false,
      "last_update_posted_date": "2024-07-15",
      "last_synced_at": "2026-09-21T18:23:06.894Z",
      "location_count": 1,
      "location_summary": "Dayton, Ohio",
      "locations": [
        {
          "city": "Dayton",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05355974"
    },
    {
      "nct_id": "NCT01200069",
      "title": "IV Ibuprofen for Post-Electroconvulsive Therapy Myalgia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression, Myalgia"
      ],
      "interventions": [
        {
          "name": "Placebo infusion",
          "type": "DRUG"
        },
        {
          "name": "ibuprofen intravenous",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 14,
      "start_date": "2010-07",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2017-03-29",
      "last_synced_at": "2026-09-21T18:23:06.894Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01200069"
    },
    {
      "nct_id": "NCT02467387",
      "title": "A Study to Assess the Effect of Intravenous Dose of (aMBMC) to Subjects With Non-ischemic Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Non-Ischemic Heart Failure"
      ],
      "interventions": [
        {
          "name": "Allogeneic Mesenchymal Bone Marrow Cells (aMBMC)",
          "type": "DRUG"
        },
        {
          "name": "Lactated Ringer's Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "CardioCell LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2014-06-01",
      "completion_date": "2017-05-11",
      "has_results": true,
      "last_update_posted_date": "2020-01-07",
      "last_synced_at": "2026-09-21T18:23:06.894Z",
      "location_count": 5,
      "location_summary": "Washington D.C., District of Columbia • Atlanta, Georgia • Chicago, Illinois + 2 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Stony Brook",
          "state": "New York"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02467387"
    },
    {
      "nct_id": "NCT01110005",
      "title": "A Trial of Intravenous Fluids During Labor",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ketosis"
      ],
      "interventions": [
        {
          "name": "D5 Lactated Ringer's Solution (D5LR)",
          "type": "OTHER"
        },
        {
          "name": "Lactated Ringer's Solution (LR)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 318,
      "start_date": "2010-04",
      "completion_date": "2013-03",
      "has_results": true,
      "last_update_posted_date": "2024-01-19",
      "last_synced_at": "2026-09-21T18:23:06.894Z",
      "location_count": 4,
      "location_summary": "Allentown, Pennsylvania • Bethlehem, Pennsylvania • Hershey, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Allentown",
          "state": "Pennsylvania"
        },
        {
          "city": "Bethlehem",
          "state": "Pennsylvania"
        },
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        },
        {
          "city": "Reading",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01110005"
    },
    {
      "nct_id": "NCT01088997",
      "title": "Pharmacokinetic Study of Milrinone in Babies With Persistent Pulmonary Hypertension of the Newborn",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Persistent Fetal Circulation Syndrome"
      ],
      "interventions": [
        {
          "name": "Milrinone Lactate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "10 Days",
        "sex": "ALL",
        "summary": "Up to 10 Days"
      },
      "enrollment_count": 12,
      "start_date": "2010-06",
      "completion_date": "2015-05",
      "has_results": true,
      "last_update_posted_date": "2016-07-12",
      "last_synced_at": "2026-09-21T18:23:06.894Z",
      "location_count": 2,
      "location_summary": "Detroit, Michigan • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01088997"
    },
    {
      "nct_id": "NCT01509040",
      "title": "Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Cardiac Arrest"
      ],
      "interventions": [
        {
          "name": "Standard Care",
          "type": "OTHER"
        },
        {
          "name": "Low Volume Hemofiltration",
          "type": "DEVICE"
        },
        {
          "name": "High Volume Hemofiltration",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2012-01",
      "completion_date": "2014-06",
      "has_results": true,
      "last_update_posted_date": "2016-06-09",
      "last_synced_at": "2026-09-21T18:23:06.894Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01509040"
    }
  ]
}