{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Investigational+COVID-19+Vaccine",
    "query": {
      "intervention": "Investigational COVID-19 Vaccine"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 28,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Investigational+COVID-19+Vaccine&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-07T02:24:34.069Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05827926",
      "title": "A Study of mRNA-based Influenza and SARS-CoV-2 (COVID-19) Multi-component Vaccines in Healthy Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "SARS-CoV-2",
        "Influenza"
      ],
      "interventions": [
        {
          "name": "Influenza Vaccine 1",
          "type": "BIOLOGICAL"
        },
        {
          "name": "mRNA-1083.1",
          "type": "BIOLOGICAL"
        },
        {
          "name": "mRNA-1083.2",
          "type": "BIOLOGICAL"
        },
        {
          "name": "mRNA-1083.3",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Investigational Influenza Vaccine 1",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Investigational COVID-19 Vaccine 1",
          "type": "BIOLOGICAL"
        },
        {
          "name": "COVID-19 Vaccine 1",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Investigational Influenza Vaccine 2",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Influenza Vaccine 2",
          "type": "BIOLOGICAL"
        },
        {
          "name": "mRNA-1083",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Investigational COVID-19 Vaccine 2",
          "type": "BIOLOGICAL"
        },
        {
          "name": "COVID-19 Vaccine 2",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "ModernaTX, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 1758,
      "start_date": "2023-04-14",
      "completion_date": "2024-12-03",
      "has_results": true,
      "last_update_posted_date": "2025-12-23",
      "last_synced_at": "2026-10-07T02:24:34.069Z",
      "location_count": 69,
      "location_summary": "Chandler, Arizona • Colton, California • Huntington Beach, California + 59 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Colton",
          "state": "California"
        },
        {
          "city": "Huntington Beach",
          "state": "California"
        },
        {
          "city": "Modesto",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05827926"
    },
    {
      "nct_id": "NCT05085613",
      "title": "Does Framing and Humor Improve the Effectiveness of Messages About COVID-19 Vaccine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Beliefs"
      ],
      "interventions": [
        {
          "name": "Corrective message framing and humor",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins Bloomberg School of Public Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "21 Years to 99 Years"
      },
      "enrollment_count": 100,
      "start_date": "2021-10-31",
      "completion_date": "2022-03-31",
      "has_results": true,
      "last_update_posted_date": "2023-08-21",
      "last_synced_at": "2026-10-07T02:24:34.069Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05085613"
    },
    {
      "nct_id": "NCT06672055",
      "title": "A Study to Evaluate VXA-CoV2-3.3 COVID-19 Vaccine Against Currently Approved/Authorized mRNA COVID-19 Injectable Booster Vaccine in Adults Previously Immunized Against COVID-19 Infection",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "SARS-CoV2",
        "COVID-19"
      ],
      "interventions": [
        {
          "name": "VXA-CoV2-3.1",
          "type": "BIOLOGICAL"
        },
        {
          "name": "COMIRNATY®",
          "type": "BIOLOGICAL"
        },
        {
          "name": "VXA-CoV2-3.3",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Vaxart",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5485,
      "start_date": "2024-10-08",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2026-06-25",
      "last_synced_at": "2026-10-07T02:24:34.069Z",
      "location_count": 145,
      "location_summary": "Anniston, Alabama • Birmingham, Alabama • Mobile, Alabama + 126 more",
      "locations": [
        {
          "city": "Anniston",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06672055"
    },
    {
      "nct_id": "NCT05541861",
      "title": "Safety and Effects of an Investigational COVID-19 Vaccine as Booster in Healthy People",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "SARS-CoV-2 Infection",
        "COVID-19"
      ],
      "interventions": [
        {
          "name": "BNT162b2 Bivalent (original/Omicron BA.4/BA.5) 30 mcg",
          "type": "BIOLOGICAL"
        },
        {
          "name": "BNT162b4 5 mcg",
          "type": "BIOLOGICAL"
        },
        {
          "name": "BNT162b4 10 mcg",
          "type": "BIOLOGICAL"
        },
        {
          "name": "BNT162b4 15 mcg",
          "type": "BIOLOGICAL"
        },
        {
          "name": "BNT162b4 30 mcg",
          "type": "BIOLOGICAL"
        },
        {
          "name": "BNT162b2 Monovalent (OMI XBB.1.5) 30 mcg",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "BioNTech SE",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 383,
      "start_date": "2022-11-08",
      "completion_date": "2024-11-22",
      "has_results": true,
      "last_update_posted_date": "2026-01-13",
      "last_synced_at": "2026-10-07T02:24:34.069Z",
      "location_count": 17,
      "location_summary": "Tempe, Arizona • Newport Beach, California • San Diego, California + 13 more",
      "locations": [
        {
          "city": "Tempe",
          "state": "Arizona"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Walnut Creek",
          "state": "California"
        },
        {
          "city": "Milford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05541861"
    },
    {
      "nct_id": "NCT05477186",
      "title": "Safety and Immunogenicity Study of a Booster Dose of the Investigational CV0501 mRNA COVID-19 Vaccine in Adults at Least 18 Years Old",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "COVID-19",
        "SARS-CoV-2"
      ],
      "interventions": [
        {
          "name": "CV0501 (3 μg)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "CV0501 (6 μg)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "CV0501 (12 μg)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "CV0501 (25 μg)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "CV0501 (50 μg)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "CV0501 (100 μg)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "CV0501 (200 μg)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 185,
      "start_date": "2022-08-12",
      "completion_date": "2023-08-18",
      "has_results": true,
      "last_update_posted_date": "2025-02-21",
      "last_synced_at": "2026-10-07T02:24:34.069Z",
      "location_count": 11,
      "location_summary": "Sacramento, California • Hollywood, Florida • Melbourne, Florida + 8 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Melbourne",
          "state": "Florida"
        },
        {
          "city": "Savannah",
          "state": "Georgia"
        },
        {
          "city": "Peoria",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05477186"
    },
    {
      "nct_id": "NCT05743335",
      "title": "A Phase 1 Study to Assess the Safety and Immunogenicity of JCXH-221, an MRNA-based Broadly Protective COVID-19 Vaccine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "COVID-19",
        "Infectious Disease"
      ],
      "interventions": [
        {
          "name": "JCXH-221",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Immorna Biotherapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 73,
      "start_date": "2023-03-07",
      "completion_date": "2023-12-01",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-10-07T02:24:34.069Z",
      "location_count": 4,
      "location_summary": "Hallandale, Florida • Savannah, Georgia • Lincoln, Nebraska + 1 more",
      "locations": [
        {
          "city": "Hallandale",
          "state": "Florida"
        },
        {
          "city": "Savannah",
          "state": "Georgia"
        },
        {
          "city": "Lincoln",
          "state": "Nebraska"
        },
        {
          "city": "Cedar Park",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05743335"
    },
    {
      "nct_id": "NCT05960097",
      "title": "A Study on the Safety and Immune Response of Investigational COVID-19 mRNA Vaccines in Healthy Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "SARS-CoV-2",
        "COVID-19"
      ],
      "interventions": [
        {
          "name": "CV0701 mRNA COVID-19 Vaccine (Low dose)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "CV0701 mRNA COVID-19 Vaccine (Medium dose)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "CV0701 mRNA COVID-19 Vaccine (High dose)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "CV0601 mRNA COVID-19 Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Control vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "CV0801 mRNA COVID-19 Vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 692,
      "start_date": "2023-08-01",
      "completion_date": "2024-08-30",
      "has_results": true,
      "last_update_posted_date": "2025-10-23",
      "last_synced_at": "2026-10-07T02:24:34.069Z",
      "location_count": 3,
      "location_summary": "Sacramento, California • Hollywood, Florida • Peoria, Illinois",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Peoria",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05960097"
    },
    {
      "nct_id": "NCT05107479",
      "title": "Effectiveness of Interactive Voice Response for COVID-19 Vaccination Training in the Democratic Republic of the Congo",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COVID-19 Vaccine Knowledge",
        "COVID-19 Vaccine Beliefs"
      ],
      "interventions": [
        {
          "name": "COVID-19 Vaccine IVR Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Condition",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8959,
      "start_date": "2021-11-09",
      "completion_date": "2022-02-10",
      "has_results": false,
      "last_update_posted_date": "2022-02-21",
      "last_synced_at": "2026-10-07T02:24:34.069Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05107479"
    },
    {
      "nct_id": "NCT06374394",
      "title": "A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a COVID-19 mRNA Vaccine in Adults Aged 50 Years and Above",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Syncytial Virus Infections"
      ],
      "interventions": [
        {
          "name": "RSVPreF3 OA investigational vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "COVID-19 mRNA vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 841,
      "start_date": "2024-04-29",
      "completion_date": "2025-03-31",
      "has_results": true,
      "last_update_posted_date": "2025-12-26",
      "last_synced_at": "2026-10-07T02:24:34.069Z",
      "location_count": 8,
      "location_summary": "Coral Gables, Florida • Savannah, Georgia • Evansville, Indiana + 5 more",
      "locations": [
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Savannah",
          "state": "Georgia"
        },
        {
          "city": "Evansville",
          "state": "Indiana"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06374394"
    },
    {
      "nct_id": "NCT04952402",
      "title": "SARS-CoV-2 Immune Responses After COVID-19 Therapy and Subsequent Vaccine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Covid19",
        "SARS-CoV2 Infection"
      ],
      "interventions": [
        {
          "name": "Study-provided Moderna mRNA-1273 COVID-19 vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Community-provided Moderna mRNA-1273 COVID-19 Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Community-Provided Pfizer-BioNTech BNT162b2 COVID-19 Vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 43,
      "start_date": "2021-07-09",
      "completion_date": "2023-01-10",
      "has_results": true,
      "last_update_posted_date": "2023-05-24",
      "last_synced_at": "2026-10-07T02:24:34.069Z",
      "location_count": 6,
      "location_summary": "Los Angeles, California • San Diego, California • Chicago, Illinois + 3 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04952402"
    }
  ]
}