{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Isometric+Training",
    "query": {
      "intervention": "Isometric Training"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 43,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Isometric+Training&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-09T17:35:26.888Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03969095",
      "title": "Tongue Pressure Resistance Training for Swallowing Impairment Post-Stroke",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke",
        "Dysphagia"
      ],
      "interventions": [
        {
          "name": "Tongue Pressure Resistance Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University Health Network, Toronto",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2019-04-01",
      "completion_date": "2022-06-16",
      "has_results": false,
      "last_update_posted_date": "2022-06-21",
      "last_synced_at": "2026-09-09T17:35:26.888Z",
      "location_count": 1,
      "location_summary": "Wheaton, Illinois",
      "locations": [
        {
          "city": "Wheaton",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03969095"
    },
    {
      "nct_id": "NCT03469271",
      "title": "Maintain Respiratory Muscle Function and Reduce Pneumonia Risk in Cancer Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "1,25 (OH)2 D3",
          "type": "DRUG"
        },
        {
          "name": "Inspiratory isometric resistance training",
          "type": "OTHER"
        },
        {
          "name": "Oral Placebo",
          "type": "DRUG"
        },
        {
          "name": "Sham Inspiratory Isometric Resistance Training",
          "type": "OTHER"
        },
        {
          "name": "Threshold Inspiratory Muscle Trainer (IMT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 63,
      "start_date": "2018-05-25",
      "completion_date": "2020-05-21",
      "has_results": true,
      "last_update_posted_date": "2023-09-26",
      "last_synced_at": "2026-09-09T17:35:26.888Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03469271"
    },
    {
      "nct_id": "NCT02467023",
      "title": "Project 4B: Lower Extremity Strength Training in ICU Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "Muscle stimulation with Niveus medical stimulator",
          "type": "DEVICE"
        },
        {
          "name": "measurement of maximal isometric twitch strength",
          "type": "DEVICE"
        },
        {
          "name": "Muscle Biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Muscle Biopsy Medication: Lidocaine",
          "type": "DRUG"
        },
        {
          "name": "Muscle Biopsy Medication: Versed",
          "type": "DRUG"
        },
        {
          "name": "Muscle Biopsy Medication: Fentanyl",
          "type": "DRUG"
        },
        {
          "name": "Blood and Urine Sampling",
          "type": "OTHER"
        },
        {
          "name": "ineffective muscle stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2015-09",
      "completion_date": "2016-07-15",
      "has_results": false,
      "last_update_posted_date": "2018-01-19",
      "last_synced_at": "2026-09-09T17:35:26.888Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02467023"
    },
    {
      "nct_id": "NCT04275037",
      "title": "The Hypotensive Effects of Home-Based Isometric Handgrip Training in Older Adults With Pre-Hypertension and Hypertension - The HoldAge Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Pre-Hypertension"
      ],
      "interventions": [
        {
          "name": "Isometric Handgrip Training",
          "type": "OTHER"
        },
        {
          "name": "Aerobic Exercise Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University Institute of Maia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 84,
      "start_date": "2021-04-12",
      "completion_date": "2023-01-30",
      "has_results": false,
      "last_update_posted_date": "2023-05-22",
      "last_synced_at": "2026-09-09T17:35:26.888Z",
      "location_count": 1,
      "location_summary": "Storrs, Connecticut",
      "locations": [
        {
          "city": "Storrs",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04275037"
    },
    {
      "nct_id": "NCT07531264",
      "title": "Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction in Chronic Stroke",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Chronic Stroke-related Upper-extremity Motor Impairment",
        "Motor Module-guided Rehabilitation Targeting Impaired Intermuscular Coordination and Motor Recovery"
      ],
      "interventions": [
        {
          "name": "Neuromuscular coordination enhancement (NICE) intervention",
          "type": "OTHER"
        },
        {
          "name": "EMG Amplitude Biofeedback Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 48,
      "start_date": "2027-08",
      "completion_date": "2032-08",
      "has_results": false,
      "last_update_posted_date": "2026-06-18",
      "last_synced_at": "2026-09-09T17:35:26.888Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07531264"
    },
    {
      "nct_id": "NCT01080196",
      "title": "Reducing Falls With RENEW in Older Adults Who Have Fallen",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Atrophy",
        "Physical Deconditioning"
      ],
      "interventions": [
        {
          "name": "RENEW",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "65 Years to 95 Years"
      },
      "enrollment_count": 134,
      "start_date": "2008-04",
      "completion_date": "2014-02",
      "has_results": true,
      "last_update_posted_date": "2022-06-21",
      "last_synced_at": "2026-09-09T17:35:26.888Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01080196"
    },
    {
      "nct_id": "NCT02920866",
      "title": "Improving Rehabilitation Outcomes After Total Hip Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Hip Arthroplasty",
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Functional Strength Integration (FSI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Group (CON)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 95,
      "start_date": "2016-11-01",
      "completion_date": "2022-03-31",
      "has_results": true,
      "last_update_posted_date": "2024-05-21",
      "last_synced_at": "2026-09-09T17:35:26.888Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02920866"
    },
    {
      "nct_id": "NCT06300619",
      "title": "Pilates+4MS: Pilates Intervention for Multiple Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Pilates+4",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pilates",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Colorado Springs",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2022-04-05",
      "completion_date": "2022-08-25",
      "has_results": false,
      "last_update_posted_date": "2024-03-08",
      "last_synced_at": "2026-09-09T17:35:26.888Z",
      "location_count": 1,
      "location_summary": "Colorado Springs, Colorado",
      "locations": [
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06300619"
    },
    {
      "nct_id": "NCT07223645",
      "title": "Handgrip Training and Brain Blood Flow Regulation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Inactivity/Low Levels of Exercise"
      ],
      "interventions": [
        {
          "name": "Handgrip Training",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Florida State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 40,
      "start_date": "2025-10-27",
      "completion_date": "2028-10-27",
      "has_results": false,
      "last_update_posted_date": "2026-06-25",
      "last_synced_at": "2026-09-09T17:35:26.888Z",
      "location_count": 1,
      "location_summary": "Tallahassee, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07223645"
    },
    {
      "nct_id": "NCT05965336",
      "title": "Walking Function in Diabetic Peripheral Neuropathy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Peripheral Neuropathy"
      ],
      "interventions": [
        {
          "name": "Clinical Evaluation",
          "type": "OTHER"
        },
        {
          "name": "Evaluation of Passive Ankle Stiffness",
          "type": "OTHER"
        },
        {
          "name": "Gait Biomechanics",
          "type": "OTHER"
        },
        {
          "name": "Gait Biofeedback",
          "type": "OTHER"
        },
        {
          "name": "Plantar Pressure Biofeedback Gait Training",
          "type": "OTHER"
        },
        {
          "name": "Propulsion Biofeedback Gait Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Florida Institute for Human and Machine Cognition",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "45 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2024-12-05",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-09-09T17:35:26.888Z",
      "location_count": 1,
      "location_summary": "Pensacola, Florida",
      "locations": [
        {
          "city": "Pensacola",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05965336"
    }
  ]
}