{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Isotonic+solution&page=22", "query": { "intervention": "Isotonic solution", "page": 22 }, "page_size": 10 }, "pagination": { "page": 22, "page_size": 10, "total_count": 1141, "total_pages": 115, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Isotonic+solution&page=23&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Isotonic+solution&page=21&page_size=10" }, "source": "remote", "last_synced_at": "2026-11-13T13:53:10.172Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00463580", "title": "A Study of Infliximab for Treatment Resistant Major Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Depression" ], "interventions": [ { "name": "Infliximab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "25 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "25 Years to 60 Years" }, "enrollment_count": 60, "start_date": "2008-12", "completion_date": "2011-06", "has_results": true, "last_update_posted_date": "2025-07-08", "last_synced_at": "2026-11-13T13:53:10.172Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00463580" }, { "nct_id": "NCT02614040", "title": "Saline Against Lactated Ringers or Plasmalyte in the Emergency Department", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Critical Illness", "Acute Kidney Injury" ], "interventions": [ { "name": "0.9% Saline", "type": "OTHER" }, { "name": "Physiologically-balanced isotonic crystalloid", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 14000, "start_date": "2016-01-01", "completion_date": "2017-06-30", "has_results": false, "last_update_posted_date": "2017-09-15", "last_synced_at": "2026-11-13T13:53:10.172Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02614040" }, { "nct_id": "NCT02508259", "title": "University of California, San Diego (UCSD) Suramin Autism Treatment-1 (SAT1) Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Autism Spectrum Disorders" ], "interventions": [ { "name": "Suramin", "type": "DRUG" }, { "name": "Saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Diego", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": "17 Years", "sex": "MALE", "summary": "4 Years to 17 Years · Male only" }, "enrollment_count": 10, "start_date": "2015-05", "completion_date": "2016-04", "has_results": true, "last_update_posted_date": "2019-07-16", "last_synced_at": "2026-11-13T13:53:10.172Z", "location_count": 1, "location_summary": "La Jolla, California", "locations": [ { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02508259" }, { "nct_id": "NCT00678379", "title": "Pediatric Tonsillectomy Pain Reduction Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Postoperative Pain" ], "interventions": [ { "name": "lidocaine (1%) + bupivacaine (0.5%)", "type": "DRUG" }, { "name": "Normal saline", "type": "DRUG" }, { "name": "Lidocaine (1%) + Bupivacaine (0.5%) + Clonidine (25mcg)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "3 Years to 17 Years" }, "enrollment_count": 120, "start_date": "2008-04", "completion_date": "2009-11", "has_results": true, "last_update_posted_date": "2017-07-02", "last_synced_at": "2026-11-13T13:53:10.172Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00678379" }, { "nct_id": "NCT01757418", "title": "Intravenous Gammaglobulin for Sickle Cell Pain Crises", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Sickle Cell Disease", "Pain" ], "interventions": [ { "name": "Immune Globulin Intravenous (IVIG)", "type": "DRUG" }, { "name": "Normal saline", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Albert Einstein College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "13 Years", "sex": "ALL", "summary": "6 Years to 13 Years" }, "enrollment_count": 300, "start_date": "2008-11", "completion_date": "2024-12-18", "has_results": false, "last_update_posted_date": "2026-03-31", "last_synced_at": "2026-11-13T13:53:10.172Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01757418" }, { "nct_id": "NCT03220958", "title": "Metoclopramide for Post Traumatic Headache", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Post-Traumatic Headache" ], "interventions": [ { "name": "Metoclopramide", "type": "DRUG" }, { "name": "Diphenhydramine", "type": "DRUG" }, { "name": "Normal saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Montefiore Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 160, "start_date": "2017-08-01", "completion_date": "2020-04-01", "has_results": true, "last_update_posted_date": "2021-11-09", "last_synced_at": "2026-11-13T13:53:10.172Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03220958" }, { "nct_id": "NCT01978535", "title": "Iron Sucrose in Adolescents With Iron Deficiency and Postural Orthostatic Tachycardia Syndrome (POTS)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Postural Orthostatic Tachycardia Syndrome" ], "interventions": [ { "name": "Iron infusion", "type": "DRUG" }, { "name": "Normal saline infusion", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "12 Years to 21 Years" }, "enrollment_count": 3, "start_date": "2014-12-17", "completion_date": "2017-09-08", "has_results": true, "last_update_posted_date": "2017-11-17", "last_synced_at": "2026-11-13T13:53:10.172Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT01978535" }, { "nct_id": "NCT02655523", "title": "A Comparison of Dexamethasone and Triamcinolone for Ultrasound-guided Occipital C2 Nerve Blocks", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Headache" ], "interventions": [ { "name": "Triamcinolone", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Normal Saline", "type": "DRUG" }, { "name": "Bupivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 0, "start_date": "2015-12", "completion_date": "2022-06", "has_results": false, "last_update_posted_date": "2022-06-23", "last_synced_at": "2026-11-13T13:53:10.172Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02655523" }, { "nct_id": "NCT01561378", "title": "Cardiac Surgery Neuroprotection Study in Elders", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Post-operative Cognitive Decline", "Post-operative Delirium" ], "interventions": [ { "name": "Aspart insulin", "type": "DRUG" }, { "name": "Normal saline", "type": "DRUG" }, { "name": "Intranasal mucosal atomizer device", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Albert Einstein College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 22, "start_date": "2012-08", "completion_date": "2014-10", "has_results": true, "last_update_posted_date": "2021-11-10", "last_synced_at": "2026-11-13T13:53:10.172Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01561378" }, { "nct_id": "NCT00976443", "title": "Effects of Gastric Antral Botulinum Toxin Injections in Obese Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "BTA", "type": "DRUG" }, { "name": "Placebo (normal saline)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 60, "start_date": "2009-09", "completion_date": "2011-09", "has_results": false, "last_update_posted_date": "2013-01-03", "last_synced_at": "2026-11-13T13:53:10.172Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00976443" } ] }