{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Knee+extension+strength&page=2",
    "query": {
      "intervention": "Knee extension strength",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Knee+extension+strength&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-28T17:04:29.379Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01058213",
      "title": "Nurse Managed Sequential Strength Training and Bicycle Training in Chronic Obstructive Pulmonary Disease (COPD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease"
      ],
      "interventions": [
        {
          "name": "Resistance training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Aerobic training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "46 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "46 Years and older"
      },
      "enrollment_count": 354,
      "start_date": "2008-11",
      "completion_date": "2013-05",
      "has_results": false,
      "last_update_posted_date": "2013-12-18",
      "last_synced_at": "2026-09-28T17:04:29.379Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01058213"
    },
    {
      "nct_id": "NCT03046875",
      "title": "The Biophysical Impact of Transcutaneous Spinal Cord Stimulation Within a Single Session",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries"
      ],
      "interventions": [
        {
          "name": "Transcutaneous Spinal Cord Stimulation",
          "type": "OTHER"
        },
        {
          "name": "Sham stimulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Hugo W. Moser Research Institute at Kennedy Krieger, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2016-10",
      "completion_date": "2017-07",
      "has_results": false,
      "last_update_posted_date": "2018-02-28",
      "last_synced_at": "2026-09-28T17:04:29.379Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03046875"
    },
    {
      "nct_id": "NCT02421523",
      "title": "Strength Training in Duchenne Muscular Dystrophy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Duchenne Muscular Dystrophy"
      ],
      "interventions": [
        {
          "name": "Aim 2 Exercise group",
          "type": "PROCEDURE"
        },
        {
          "name": "Aim 1 Exercise Dosing",
          "type": "PROCEDURE"
        },
        {
          "name": "Aim 2 Control group",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "10 Years",
        "sex": "MALE",
        "summary": "7 Years to 10 Years · Male only"
      },
      "enrollment_count": 18,
      "start_date": "2015-05-30",
      "completion_date": "2018-10-08",
      "has_results": false,
      "last_update_posted_date": "2019-03-06",
      "last_synced_at": "2026-09-28T17:04:29.379Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02421523"
    },
    {
      "nct_id": "NCT07106450",
      "title": "Training Induced Muscle-Adipose EV Communication",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prediabetes"
      ],
      "interventions": [
        {
          "name": "Acute Resistance Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yuan Wen",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "30 Years to 55 Years"
      },
      "enrollment_count": 40,
      "start_date": "2026-09",
      "completion_date": "2028-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-10",
      "last_synced_at": "2026-09-28T17:04:29.379Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07106450"
    },
    {
      "nct_id": "NCT01618240",
      "title": "Predictors of the Ability to Protect the Airway in Long-term Ventilated Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Swallowing Disorder",
        "Aspiration",
        "Long Term Ventilation"
      ],
      "interventions": [
        {
          "name": "Muscle Strength Measurement",
          "type": "OTHER"
        },
        {
          "name": "Ventilator",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2011-01",
      "completion_date": "2012-04",
      "has_results": true,
      "last_update_posted_date": "2014-10-13",
      "last_synced_at": "2026-09-28T17:04:29.379Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01618240"
    },
    {
      "nct_id": "NCT05455346",
      "title": "Eccentric Training Effects on Hamstrings Structure, Strength, and Sprint Performance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exercise Training",
        "Sport",
        "Running",
        "Ultrasound Imaging",
        "Elastography",
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Ultrasound imaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hamstring Eccentric Strength Testing",
          "type": "OTHER"
        },
        {
          "name": "Maximal 60 m Sprint",
          "type": "OTHER"
        },
        {
          "name": "Romanian Deadlift",
          "type": "OTHER"
        },
        {
          "name": "Nordic hamstring exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "18 Years to 25 Years"
      },
      "enrollment_count": 32,
      "start_date": "2022-12-02",
      "completion_date": "2023-12-08",
      "has_results": false,
      "last_update_posted_date": "2023-12-21",
      "last_synced_at": "2026-09-28T17:04:29.379Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05455346"
    },
    {
      "nct_id": "NCT00519922",
      "title": "A Study of the Effectiveness of Different Types of Exercise for People With Knee Osteoarthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Kinesthesia, Balance, and Agility (KBA) Exercise",
          "type": "OTHER"
        },
        {
          "name": "Standard LE Strength Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Arthritis Research Institute of America",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2008-01",
      "completion_date": "2008-07",
      "has_results": false,
      "last_update_posted_date": "2008-07-22",
      "last_synced_at": "2026-09-28T17:04:29.379Z",
      "location_count": 1,
      "location_summary": "Clearwater, Florida",
      "locations": [
        {
          "city": "Clearwater",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00519922"
    },
    {
      "nct_id": "NCT02112604",
      "title": "Predictors of Upper Airway Function and Sleep-disordered Breathing in the Critically Ill",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Critically Ill",
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Ventilator",
          "type": "DEVICE"
        },
        {
          "name": "Alice PDx",
          "type": "DEVICE"
        },
        {
          "name": "Pulmonary function test",
          "type": "OTHER"
        },
        {
          "name": "Muscle strength tests",
          "type": "OTHER"
        },
        {
          "name": "Grip strength measurement",
          "type": "OTHER"
        },
        {
          "name": "Sedatives and muscle relaxants given in the ICU",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2011-07",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2016-03-17",
      "last_synced_at": "2026-09-28T17:04:29.379Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02112604"
    },
    {
      "nct_id": "NCT00325858",
      "title": "A Study Comparing the Effectiveness and Safety of Varying Dose Strengths (100, 200, 300 and 400 mg) of Extended-release Tramadol HCl With Placebo for the Treatment of Osteoarthritis(OA) of the Knee and/or Hip",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Tramadol HCl ER",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bausch Health Americas, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "18 Years to 74 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2002-01",
      "completion_date": "2003-12",
      "has_results": false,
      "last_update_posted_date": "2012-08-27",
      "last_synced_at": "2026-09-28T17:04:29.379Z",
      "location_count": 1,
      "location_summary": "Duncansville, Pennsylvania",
      "locations": [
        {
          "city": "Duncansville",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00325858"
    },
    {
      "nct_id": "NCT01238926",
      "title": "Vitamin B6, B12, Folic Acid and Exercise in Parkinson's Disease",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease"
      ],
      "interventions": [
        {
          "name": "PD vitamin supplementation",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "PD exercise intervention",
          "type": "OTHER"
        },
        {
          "name": "PD vitamin + exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "New York Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "50 Years to 80 Years"
      },
      "enrollment_count": 40,
      "start_date": "2008-05",
      "completion_date": "2010-11",
      "has_results": false,
      "last_update_posted_date": "2010-11-11",
      "last_synced_at": "2026-09-28T17:04:29.379Z",
      "location_count": 1,
      "location_summary": "Old Westbury, New York",
      "locations": [
        {
          "city": "Old Westbury",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01238926"
    }
  ]
}