{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=LDX+50+mg", "query": { "intervention": "LDX 50 mg" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 15, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=LDX+50+mg&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-05T08:46:24.300Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00735371", "title": "Efficacy and Safety of Lisdexamfetamine Dimesylate (LDX) in Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Attention Deficit Hyperactivity Disorder (ADHD)" ], "interventions": [ { "name": "LDX 30 mg", "type": "DRUG" }, { "name": "LDX 50 mg", "type": "DRUG" }, { "name": "LDX 70 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shire", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "13 Years to 17 Years" }, "enrollment_count": 314, "start_date": "2008-10-08", "completion_date": "2009-04-06", "has_results": true, "last_update_posted_date": "2021-06-14", "last_synced_at": "2026-09-05T08:46:24.300Z", "location_count": 45, "location_summary": "Little Rock, Arkansas • El Centro, California • Rolling Hills Estates, California + 40 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "El Centro", "state": "California" }, { "city": "Rolling Hills Estates", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Wildomar", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00735371" }, { "nct_id": "NCT01986777", "title": "LDX for the Treatment of Cognitive Functioning Issues in Women Post-Oophorectomy", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cognitive Impairments", "RRSO" ], "interventions": [ { "name": "lisdexamfetamine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "30 Years", "maximum_age": "60 Years", "sex": "FEMALE", "summary": "30 Years to 60 Years · Female only" }, "enrollment_count": 0, "start_date": "2013-07", "completion_date": "2013-12", "has_results": false, "last_update_posted_date": "2017-09-18", "last_synced_at": "2026-09-05T08:46:24.300Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01986777" }, { "nct_id": "NCT00764868", "title": "Vyvanse Adolescent Open-Label Safety and Efficacy Extension Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "ADHD" ], "interventions": [ { "name": "Lisdexamfetamine Dimesylate (LDX)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shire", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "13 Years to 17 Years" }, "enrollment_count": 269, "start_date": "2008-11-13", "completion_date": "2010-04-22", "has_results": true, "last_update_posted_date": "2021-06-14", "last_synced_at": "2026-09-05T08:46:24.300Z", "location_count": 45, "location_summary": "Little Rock, Arkansas • El Centro, California • Rolling Hills Estates, California + 40 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "El Centro", "state": "California" }, { "city": "Rolling Hills Estates", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Wildomar", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00764868" }, { "nct_id": "NCT00905424", "title": "Exploratory Study of SPD489 in Adults With Major Depressive Disorder (MDD) as Augmentation Therapy to an Antidepressant", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Antidepressant + SPD489 (lisdexamfetamine dimesylate)", "type": "DRUG" }, { "name": "Antidepressant + placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shire", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 246, "start_date": "2009-07-30", "completion_date": "2010-08-04", "has_results": true, "last_update_posted_date": "2021-06-14", "last_synced_at": "2026-09-05T08:46:24.300Z", "location_count": 15, "location_summary": "Newport Beach, California • San Diego, California • Bradenton, Florida + 12 more", "locations": [ { "city": "Newport Beach", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Bradenton", "state": "Florida" }, { "city": "Fort Myers", "state": "Florida" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00905424" }, { "nct_id": "NCT01657019", "title": "Open Label Extension in Adults With Binge Eating Disorder (BED)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Binge Eating Disorder" ], "interventions": [ { "name": "Lisdexamfetamine dimesylate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shire", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 604, "start_date": "2012-08-21", "completion_date": "2014-10-21", "has_results": true, "last_update_posted_date": "2021-06-09", "last_synced_at": "2026-09-05T08:46:24.300Z", "location_count": 84, "location_summary": "Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 77 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Corona", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01657019" }, { "nct_id": "NCT01071044", "title": "Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Chronic Fatigue Syndrome", "Cognitive Impairments" ], "interventions": [ { "name": "Lisdexamfetamine Dimesylate", "type": "DRUG" }, { "name": "Placebo \"30, 50 or 70 mg\"", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Rochester Center for Behavioral Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 26, "start_date": "2009-11", "completion_date": "2011-03", "has_results": true, "last_update_posted_date": "2025-09-09", "last_synced_at": "2026-09-05T08:46:24.300Z", "location_count": 1, "location_summary": "Rochester Hills, Michigan", "locations": [ { "city": "Rochester Hills", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01071044" }, { "nct_id": "NCT01718483", "title": "SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Binge Eating Disorder" ], "interventions": [ { "name": "SPD489 (Lisdexamfetamine dimesylate)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shire", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 383, "start_date": "2012-11-26", "completion_date": "2013-09-25", "has_results": true, "last_update_posted_date": "2021-06-08", "last_synced_at": "2026-09-05T08:46:24.300Z", "location_count": 43, "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Corona, California + 40 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Corona", "state": "California" }, { "city": "Encino", "state": "California" }, { "city": "Los Alamitos", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01718483" }, { "nct_id": "NCT01718509", "title": "SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Binge Eating Disorder" ], "interventions": [ { "name": "SPD489 (Lisdexamfetamine dimesylate)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shire", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 390, "start_date": "2012-11-26", "completion_date": "2013-09-20", "has_results": true, "last_update_posted_date": "2021-07-16", "last_synced_at": "2026-09-05T08:46:24.300Z", "location_count": 45, "location_summary": "Tucson, Arizona • Beverly Hills, California • La Jolla, California + 42 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Oceanside", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01718509" }, { "nct_id": "NCT00697515", "title": "Safety and Efficacy Workplace Environment Study of Lisdexamfetamine Dimesylate (LDX) in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "ADHD" ], "interventions": [ { "name": "LDX", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shire", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 142, "start_date": "2008-07-18", "completion_date": "2008-12-20", "has_results": true, "last_update_posted_date": "2021-06-09", "last_synced_at": "2026-09-05T08:46:24.300Z", "location_count": 5, "location_summary": "Little Rock, Arkansas • Irvine, California • Overland Park, Kansas + 2 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Irvine", "state": "California" }, { "city": "Overland Park", "state": "Kansas" }, { "city": "Las Vegas", "state": "Nevada" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00697515" }, { "nct_id": "NCT00807222", "title": "Effect of Vyvanse on Sleep in Children Aged 6-12 Years With Attention Deficit Hyperactivity Disorder (ADHD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Attention Deficit Hyperactivity Disorder", "Sleep" ], "interventions": [ { "name": "lisdexamfetamine dimesylate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Clinical Study Centers, LLC", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "12 Years", "sex": "ALL", "summary": "6 Years to 12 Years" }, "enrollment_count": 24, "start_date": "2008-04", "completion_date": "2008-08", "has_results": false, "last_update_posted_date": "2008-12-11", "last_synced_at": "2026-09-05T08:46:24.300Z", "location_count": 1, "location_summary": "Little Rock, Arkansas", "locations": [ { "city": "Little Rock", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00807222" } ] }