{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=LS11",
    "query": {
      "intervention": "LS11"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-09T13:38:10.122Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00716469",
      "title": "Phase I Clinical Study of the Safety of Photodynamic Therapy (PDT) Using LS11 in Children With Plexiform Neurofibromas",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Neurofibroma"
      ],
      "interventions": [
        {
          "name": "LS11",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "3 Years to 21 Years"
      },
      "enrollment_count": 7,
      "start_date": "2008-07",
      "completion_date": "2012-07",
      "has_results": false,
      "last_update_posted_date": "2015-04-15",
      "last_synced_at": "2026-09-09T13:38:10.122Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00716469"
    },
    {
      "nct_id": "NCT00068068",
      "title": "Photodynamic Therapy With Talaporfin Sodium (LS11) in Treating Patients With Refractory Colorectal Liver Metastases",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Liver Metastasis",
        "Colorectal Neoplasms",
        "Liver Neoplasms",
        "Neoplasm Metastasis"
      ],
      "interventions": [
        {
          "name": "Talaporfin sodium (LS11)",
          "type": "DRUG"
        },
        {
          "name": "LED-based light infusion device",
          "type": "DEVICE"
        },
        {
          "name": "Light emitting diodes (LED)",
          "type": "DEVICE"
        },
        {
          "name": "Photodynamic therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Phototherapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Chemotherapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Light Sciences LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2003-10",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2006-09-19",
      "last_synced_at": "2026-09-09T13:38:10.122Z",
      "location_count": 5,
      "location_summary": "Denver, Colorado • Greenville, North Carolina • Philadelphia, Pennsylvania + 2 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Greenville",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00068068"
    },
    {
      "nct_id": "NCT00028405",
      "title": "Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Liver Metastasis",
        "Pelvic Cancer",
        "Head and Neck Cancer",
        "Sarcoma",
        "Rectal Cancer",
        "Breast Cancer",
        "Colorectal Cancer",
        "Mouth Cancer"
      ],
      "interventions": [
        {
          "name": "LS 11(Taporfin Sodium)",
          "type": "DRUG"
        },
        {
          "name": "Lumaflex Light Delivery Catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Light Sciences LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2001-11",
      "completion_date": "2002-12",
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-09-09T13:38:10.122Z",
      "location_count": 6,
      "location_summary": "Tucson, Arizona • Detroit, Michigan • Greenville, North Carolina + 2 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Greenville",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00028405"
    },
    {
      "nct_id": "NCT01924273",
      "title": "Novel Treatment for Port Wine Stain Birthmarks",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Port-Wine Stain"
      ],
      "interventions": [
        {
          "name": "Talaporfin sodium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2013-06",
      "completion_date": "2017-07-03",
      "has_results": false,
      "last_update_posted_date": "2022-11-01",
      "last_synced_at": "2026-09-09T13:38:10.122Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01924273"
    },
    {
      "nct_id": "NCT00102115",
      "title": "Study of Talaporfin Sodium Photodynamic Therapy to Treat Advanced Age Related Macular Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Macular Degeneration",
        "Choroidal Neovascularization"
      ],
      "interventions": [
        {
          "name": "Talaporfin Sodium (LS11) Photodynamic Therapy (PDT)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Light Sciences LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 27,
      "start_date": "2004-12",
      "completion_date": "2006-01",
      "has_results": false,
      "last_update_posted_date": "2010-03-12",
      "last_synced_at": "2026-09-09T13:38:10.122Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00102115"
    },
    {
      "nct_id": "NCT00083785",
      "title": "Study of the Litx™ System Combined With Chemotherapy in Patients With Colorectal Liver Metastases",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Liver Metastasis",
        "Colorectal Neoplasms",
        "Liver Neoplasms",
        "Neoplasm Metastasis"
      ],
      "interventions": [
        {
          "name": "Talaporfin sodium (LS11)",
          "type": "DRUG"
        },
        {
          "name": "LED-based light infusion device",
          "type": "DEVICE"
        },
        {
          "name": "Light emitting diodes (LED)",
          "type": "DEVICE"
        },
        {
          "name": "Photodynamic therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Phototherapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Chemotherapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Light Sciences LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2004-05",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2007-04-11",
      "last_synced_at": "2026-09-09T13:38:10.122Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00083785"
    },
    {
      "nct_id": "NCT00709488",
      "title": "Phase 1 Study of the Litx™ BPH System in Patients With Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Benign Prostatic Hyperplasia",
        "Lower Urinary Tract Symptoms"
      ],
      "interventions": [
        {
          "name": "Talaporfin sodium",
          "type": "DRUG"
        },
        {
          "name": "Placement of device in prostate urethra",
          "type": "PROCEDURE"
        },
        {
          "name": "Transurethral illumination with light emitting diodes (Litx™ BPH Device)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Light Sciences Oncology",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 12,
      "start_date": "2008-06",
      "completion_date": "2011-04",
      "has_results": false,
      "last_update_posted_date": "2012-11-16",
      "last_synced_at": "2026-09-09T13:38:10.122Z",
      "location_count": 6,
      "location_summary": "Anchorage, Alaska • Los Angeles, California • Portland, Oregon + 3 more",
      "locations": [
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "Mountlake Terrace",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00709488"
    },
    {
      "nct_id": "NCT02326454",
      "title": "A Placebo Controlled Study of MR901 (Talaporfin Sodium Sodium + a Drug-activating Device) for the Relief of Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Benign Prostatic Hyperplasia"
      ],
      "interventions": [
        {
          "name": "talaporfin sodium",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        },
        {
          "name": "Drug Activator 100 J/cm",
          "type": "DEVICE"
        },
        {
          "name": "Drug Activator 200 J/cm",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Light Sciences Oncology",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "40 Years and older · Male only"
      },
      "enrollment_count": 225,
      "start_date": "2014-11",
      "completion_date": "2017-03-29",
      "has_results": false,
      "last_update_posted_date": "2018-08-08",
      "last_synced_at": "2026-09-09T13:38:10.122Z",
      "location_count": 41,
      "location_summary": "Anniston, Alabama • Huntsville, Alabama • Anchorage, Alaska + 37 more",
      "locations": [
        {
          "city": "Anniston",
          "state": "Alabama"
        },
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02326454"
    }
  ]
}