{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lactate+Clearance",
    "query": {
      "intervention": "Lactate Clearance"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 5,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-08T09:42:03.805Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00372502",
      "title": "Clinical Trial of the Optimal Endpoint of Early Sepsis Resuscitation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe Sepsis",
        "Septic Shock"
      ],
      "interventions": [
        {
          "name": "Modified EGDT",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard EGDT",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Institute of General Medical Sciences (NIGMS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2007-01",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2009-01-14",
      "last_synced_at": "2026-09-08T09:42:03.805Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts • Camden, New Jersey • Charlotte, North Carolina",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Camden",
          "state": "New Jersey"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00372502"
    },
    {
      "nct_id": "NCT05478746",
      "title": "Effects of Flourish HEC on Localized Provoked Vulvodynia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vulvodynia",
        "Vestibulodynia",
        "Vulvar Diseases",
        "Vulvar Vestibulitis",
        "Vulvar Pain"
      ],
      "interventions": [
        {
          "name": "BioNourish, a component of the Flourish HEC kit",
          "type": "DEVICE"
        },
        {
          "name": "Control - no intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Vaginal Biome Science",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "52 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 52 Years · Female only"
      },
      "enrollment_count": 7,
      "start_date": "2022-09-26",
      "completion_date": "2024-01-15",
      "has_results": false,
      "last_update_posted_date": "2024-02-06",
      "last_synced_at": "2026-09-08T09:42:03.805Z",
      "location_count": 1,
      "location_summary": "Virginia Beach, Virginia",
      "locations": [
        {
          "city": "Virginia Beach",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05478746"
    },
    {
      "nct_id": "NCT01128413",
      "title": "Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shock"
      ],
      "interventions": [
        {
          "name": "Cheetah NICOM® PLRT",
          "type": "DEVICE"
        },
        {
          "name": "USCOM ® (Ultrasound Cardiac Output Monitor)",
          "type": "DEVICE"
        },
        {
          "name": "Inferior Vena Cava (IVC) Ultrasound Collapsibility",
          "type": "DEVICE"
        },
        {
          "name": "CURVES Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lactate Clearance",
          "type": "BIOLOGICAL"
        },
        {
          "name": "500ml Normal Saline Bolus",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Clinician Discretion Intravenous Fluid Management",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL",
        "BIOLOGICAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2010-07",
      "completion_date": "2013-11",
      "has_results": true,
      "last_update_posted_date": "2016-04-01",
      "last_synced_at": "2026-09-08T09:42:03.805Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01128413"
    },
    {
      "nct_id": "NCT05397782",
      "title": "Effects of Flourish on Recurrent Urinary Tract Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Urinary Tract Infections"
      ],
      "interventions": [
        {
          "name": "BioNourish, a component of Flourish HEC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vaginal Biome Science",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "52 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 52 Years · Female only"
      },
      "enrollment_count": 14,
      "start_date": "2022-09-26",
      "completion_date": "2024-02-21",
      "has_results": false,
      "last_update_posted_date": "2024-03-07",
      "last_synced_at": "2026-09-08T09:42:03.805Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05397782"
    },
    {
      "nct_id": "NCT02218983",
      "title": "The Prognostic Value of Limited Transthoracic Echocardiogram (LTTE) During Trauma Resuscitation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patients Who Are in Shock and Intubated in the Trauma Bay (TB)"
      ],
      "interventions": [
        {
          "name": "Limited Transthoracic Echocardiogram (LTTE, SonoSite Ultrasound)",
          "type": "DEVICE"
        },
        {
          "name": "Usual care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Riverside University Health System Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 110,
      "start_date": "2014-06",
      "completion_date": "2018-06",
      "has_results": false,
      "last_update_posted_date": "2017-04-17",
      "last_synced_at": "2026-09-08T09:42:03.805Z",
      "location_count": 1,
      "location_summary": "Moreno Valley, California",
      "locations": [
        {
          "city": "Moreno Valley",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02218983"
    }
  ]
}