{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lapaquistat+acetate", "query": { "intervention": "Lapaquistat acetate" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 12, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lapaquistat+acetate&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-12T06:20:59.086Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00249899", "title": "Efficacy of Lapaquistat Acetate Alone or Combined With High-Dose Statin Therapy in Subjects With Hypercholesterolemia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypercholesterolemia" ], "interventions": [ { "name": "Lapaquistat acetate and stable statin therapy", "type": "DRUG" }, { "name": "Stable statin therapy", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 649, "start_date": "2005-11", "completion_date": "2007-03", "has_results": false, "last_update_posted_date": "2012-05-24", "last_synced_at": "2026-09-12T06:20:59.086Z", "location_count": 13, "location_summary": "Santa Ana, California • Chicago, Illinois • Iowa City, Iowa + 10 more", "locations": [ { "city": "Santa Ana", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Kansas City", "state": "Kansas" }, { "city": "Auburn", "state": "Maine" } ], "official_url": "https://clinicaltrials.gov/study/NCT00249899" }, { "nct_id": "NCT00813527", "title": "Effect of Lapaquistat Acetate Combined With Fenofibrate on Blood Cholesterol Levels", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hyperlipidemias" ], "interventions": [ { "name": "Lapaquistat acetate and fenofibrate", "type": "DRUG" }, { "name": "Fenofibrate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 213, "start_date": "2006-02", "completion_date": "2007-01", "has_results": false, "last_update_posted_date": "2012-05-24", "last_synced_at": "2026-09-12T06:20:59.086Z", "location_count": 32, "location_summary": "Huntsville, Alabama • Sierra Vista, Arizona • Beverly Hills, California + 29 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Sierra Vista", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Spring Valley", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00813527" }, { "nct_id": "NCT00143676", "title": "Efficacy of Lapaquistat Acetate and Atorvastatin on Blood Cholesterol Levels in Subjects With Primary Hypercholesterolemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypercholesterolemia" ], "interventions": [ { "name": "Lapaquistat acetate and atorvastatin", "type": "DRUG" }, { "name": "Atorvastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 448, "start_date": "2005-08", "completion_date": "2006-08", "has_results": false, "last_update_posted_date": "2012-05-24", "last_synced_at": "2026-09-12T06:20:59.086Z", "location_count": 78, "location_summary": "Birmingham, Alabama • Northport, Alabama • Sierra Vista, Arizona + 75 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Northport", "state": "Alabama" }, { "city": "Sierra Vista", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Jonesboro", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00143676" }, { "nct_id": "NCT00286481", "title": "Efficacy of Lapaquistat Acetate Alone or Combined With Simvastatin in Subjects With Hypercholesterolemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypercholesterolemia" ], "interventions": [ { "name": "Lapaquistat acetate and simvastatin", "type": "DRUG" }, { "name": "Simvastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1362, "start_date": "2006-03", "completion_date": "2007-05", "has_results": false, "last_update_posted_date": "2012-05-24", "last_synced_at": "2026-09-12T06:20:59.086Z", "location_count": 50, "location_summary": "Huntsville, Alabama • Chandler, Arizona • Scottsdale, Arizona + 47 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Chandler", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Sierra Vista", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00286481" }, { "nct_id": "NCT00532311", "title": "Efficacy of Lapaquistat Acetate Co-Administered With Statins in Subjects With Hypercholesterolemia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypercholesterolemia" ], "interventions": [ { "name": "Lapaquistat acetate and stable statin therapy", "type": "DRUG" }, { "name": "Stable statin therapy", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 411, "start_date": "2007-07", "completion_date": "2008-04", "has_results": false, "last_update_posted_date": "2016-06-22", "last_synced_at": "2026-09-12T06:20:59.086Z", "location_count": 86, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 83 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Tuscaloosa", "state": "Alabama" }, { "city": "Chandler", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00532311" }, { "nct_id": "NCT00251680", "title": "Efficacy of Lapaquistat Acetate in Subjects Currently Treated With Lipid-Lowering Therapy.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 2 Diabetes" ], "interventions": [ { "name": "Lapaquistat acetate and lipid-lowering therapy", "type": "DRUG" }, { "name": "Lipid-lowering therapy", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 400, "start_date": "2005-10", "completion_date": "2007-05", "has_results": false, "last_update_posted_date": "2012-05-24", "last_synced_at": "2026-09-12T06:20:59.086Z", "location_count": 18, "location_summary": "Tucson, Arizona • Artesia, California • Jacksonville, Florida + 15 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Artesia", "state": "California" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Dunwoody", "state": "Georgia" }, { "city": "Idaho Falls", "state": "Idaho" } ], "official_url": "https://clinicaltrials.gov/study/NCT00251680" }, { "nct_id": "NCT00865228", "title": "Efficacy of Lapaquistat Acetate in Subjects With Hypercholesterolemia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hypercholesterolemia" ], "interventions": [ { "name": "Lapaquistat acetate", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 224, "start_date": "2007-07", "completion_date": "2007-11", "has_results": false, "last_update_posted_date": "2012-05-24", "last_synced_at": "2026-09-12T06:20:59.086Z", "location_count": 22, "location_summary": "Long Beach, California • Sacramento, California • San Diego, California + 19 more", "locations": [ { "city": "Long Beach", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Hollywood", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00865228" }, { "nct_id": "NCT00263081", "title": "Efficacy of Lapaquistat Acetate Co-Administered With Current Lipid-Lowering Treatment on Blood Cholesterol Levels in Subjects With Homozygous Familial Hypercholesterolemia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hypercholesterolemia" ], "interventions": [ { "name": "Lapaquistat acetate and current lipid-lowering treatment", "type": "DRUG" }, { "name": "Current lipid-lowering treatment", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "8 Years", "maximum_age": null, "sex": "ALL", "summary": "8 Years and older" }, "enrollment_count": 44, "start_date": "2005-11", "completion_date": "2007-03", "has_results": false, "last_update_posted_date": "2012-05-24", "last_synced_at": "2026-09-12T06:20:59.086Z", "location_count": 2, "location_summary": "Cincinnati, Ohio • Columbus, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" }, { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00263081" }, { "nct_id": "NCT00890448", "title": "Case Control Study of Pharmacogenomic Factors Associated With Hepatocellular Injury Following Exposure to Lapaquistat Acetate", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Toxicity" ], "interventions": [ { "name": "Pharmacogenomic whole blood sampling", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 66, "start_date": "2009-05", "completion_date": "2010-05", "has_results": false, "last_update_posted_date": "2012-05-24", "last_synced_at": "2026-09-12T06:20:59.086Z", "location_count": 4, "location_summary": "Jacksonville, Florida • Jupiter, Florida • Idaho Falls, Idaho + 1 more", "locations": [ { "city": "Jacksonville", "state": "Florida" }, { "city": "Jupiter", "state": "Florida" }, { "city": "Idaho Falls", "state": "Idaho" }, { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00890448" }, { "nct_id": "NCT00143663", "title": "Effect of Lapaquistat Acetate on Blood Cholesterol Levels in Subjects With Elevated Cholesterol", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Dyslipidemia" ], "interventions": [ { "name": "Lapaquistat Acetate", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 361, "start_date": "2005-09", "completion_date": "2006-04", "has_results": false, "last_update_posted_date": "2012-05-24", "last_synced_at": "2026-09-12T06:20:59.086Z", "location_count": 47, "location_summary": "Northport, Alabama • Mesa, Arizona • Chula Vista, California + 44 more", "locations": [ { "city": "Northport", "state": "Alabama" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Chula Vista", "state": "California" }, { "city": "Encinitas", "state": "California" }, { "city": "Long Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00143663" } ] }