{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Laser+%2B+ICG",
    "query": {
      "intervention": "Laser + ICG"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Laser+%2B+ICG&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-12T23:17:32.380Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02918383",
      "title": "Subchondral Perfusion Mapping Using Indocyanin Green Laser",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Distal Femoral",
        "Proximal Tibial",
        "Knee Surgery"
      ],
      "interventions": [
        {
          "name": "Indocyanin Green Dye (ICG)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 2,
      "start_date": "2016-06",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2020-01-07",
      "last_synced_at": "2026-09-12T23:17:32.380Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02918383"
    },
    {
      "nct_id": "NCT05332405",
      "title": "SPY Angiography To Assist With Ulnar Nerve Transposition at the Elbow",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cubital Tunnel Syndrome"
      ],
      "interventions": [
        {
          "name": "Indocyanine green",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 0,
      "start_date": "2022-05-26",
      "completion_date": "2024-04-01",
      "has_results": false,
      "last_update_posted_date": "2023-06-29",
      "last_synced_at": "2026-09-12T23:17:32.380Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05332405"
    },
    {
      "nct_id": "NCT04633512",
      "title": "Safety and Feasibility of ActivSightTM in Human",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Cholecystitis",
        "Colorectal Cancer",
        "Diverticulitis, Colonic",
        "Obesity, Morbid",
        "Inflammatory Bowel Diseases"
      ],
      "interventions": [
        {
          "name": "ActivSight",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Activ Surgical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 67,
      "start_date": "2020-11-17",
      "completion_date": "2025-01",
      "has_results": false,
      "last_update_posted_date": "2024-02-21",
      "last_synced_at": "2026-09-12T23:17:32.380Z",
      "location_count": 3,
      "location_summary": "Buffalo, New York • Houston, Texas • Sugar Land, Texas",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Sugar Land",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04633512"
    },
    {
      "nct_id": "NCT05591053",
      "title": "Utility and Usability of ActivSight™ Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow During Esophageal Surgery in Humans",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Esophagus Cancer",
        "Esophageal Cancer",
        "Esophageal Neoplasms",
        "Esophageal Diseases",
        "Esophageal Adenocarcinoma",
        "Esophageal Squamous Cell Carcinoma",
        "Esophagus SCC",
        "Esophagus Tumor",
        "Esophagus Adenocarcinoma",
        "Esophagus Neoplasm"
      ],
      "interventions": [
        {
          "name": "ActivSight",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Activ Surgical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2023-04-01",
      "completion_date": "2025-01",
      "has_results": false,
      "last_update_posted_date": "2024-02-21",
      "last_synced_at": "2026-09-12T23:17:32.380Z",
      "location_count": 2,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05591053"
    },
    {
      "nct_id": "NCT07004764",
      "title": "Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Achilles Tendon Repairs/Reconstructions",
        "Pilon Fracture of Tibia",
        "Tibial Plateau Fracture",
        "Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)",
        "Calcaneus Fractures",
        "Talus Fracture",
        "Wound Infection Deep",
        "Wound Infection Post-Traumatic",
        "Wound Dehiscence, Surgical"
      ],
      "interventions": [
        {
          "name": "Nitroglycerin Ointment 2%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2026-11",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-09-12T23:17:32.380Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07004764"
    },
    {
      "nct_id": "NCT07165340",
      "title": "Evaluation of Lymphatic Response to Physiotherapy in Patients With Swelling Associated With Superficial Venous Disease",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Chronic Venous Disease"
      ],
      "interventions": [
        {
          "name": "Indocyanine Green near infrared fluorescence imaging",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "advanced pneumatic compression",
          "type": "DEVICE"
        },
        {
          "name": "Duplex ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "compression wrap",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "DEVICE",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2025-09",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2025-09-16",
      "last_synced_at": "2026-09-12T23:17:32.380Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07165340"
    },
    {
      "nct_id": "NCT03964831",
      "title": "Study Comparing the P200TxE and P200DTx",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Retinal Disease"
      ],
      "interventions": [
        {
          "name": "P200TxE",
          "type": "DEVICE"
        },
        {
          "name": "P200DTx",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Optos, PLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2019-06-18",
      "completion_date": "2020-01-14",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-09-12T23:17:32.380Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03964831"
    },
    {
      "nct_id": "NCT01554267",
      "title": "The Use of Laser-Assisted Indocyanine Green Dye Angiography to Predict Mastectomy Skin Flap Viability",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Breast Reconstruction",
        "Mastectomy"
      ],
      "interventions": [
        {
          "name": "Laser-Assisted ICG Dye Angiography (SPY System)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 45,
      "start_date": "2014-01",
      "completion_date": "2015-05",
      "has_results": false,
      "last_update_posted_date": "2014-05-13",
      "last_synced_at": "2026-09-12T23:17:32.380Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01554267"
    },
    {
      "nct_id": "NCT03351387",
      "title": "Wound Necrosis in Lower Extremity Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Extremity Lower Wounds"
      ],
      "interventions": [
        {
          "name": "SPY Intra-operative Angiography",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2017-10-20",
      "completion_date": "2018-04-18",
      "has_results": false,
      "last_update_posted_date": "2021-12-17",
      "last_synced_at": "2026-09-12T23:17:32.380Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03351387"
    },
    {
      "nct_id": "NCT00948519",
      "title": "Laser Assisted Treatment of Chronic Sinusitis With and Without Light Activated Agents",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rhinosinusitis"
      ],
      "interventions": [
        {
          "name": "Laser + ICG",
          "type": "DEVICE"
        },
        {
          "name": "Laser only",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "New York Head & Neck Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2009-05",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2011-07-22",
      "last_synced_at": "2026-09-12T23:17:32.380Z",
      "location_count": 3,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00948519"
    }
  ]
}