{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Left+Atrial+Appendage+Device+Implant", "query": { "intervention": "Left Atrial Appendage Device Implant" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 23, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Left+Atrial+Appendage+Device+Implant&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-26T12:40:48.092Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02226133", "title": "Video-Assisted Left Atrial Appendage Exclusion Trial", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Diseases" ], "interventions": [ { "name": "LAAx, Inc. TigerPaw® System II", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "LAAx, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2015-04", "completion_date": "2015-12", "has_results": false, "last_update_posted_date": "2015-05-05", "last_synced_at": "2026-09-26T12:40:48.092Z", "location_count": 4, "location_summary": "Pleasanton, California • Baltimore, Maryland • Danville, Pennsylvania + 1 more", "locations": [ { "city": "Pleasanton", "state": "California" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Danville", "state": "Pennsylvania" }, { "city": "Wynnewood", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02226133" }, { "nct_id": "NCT04394546", "title": "CHAMPION-AF Clinical Trial", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Atrial Fibrillation", "Stroke", "Bleeding" ], "interventions": [ { "name": "WATCHMAN FLX LAAC Device", "type": "DEVICE" }, { "name": "Non-Vitamin K Oral Anticoagulant", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Boston Scientific Corporation", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3000, "start_date": "2020-10-15", "completion_date": "2027-12", "has_results": false, "last_update_posted_date": "2026-09-11", "last_synced_at": "2026-09-26T12:40:48.092Z", "location_count": 95, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 83 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT04394546" }, { "nct_id": "NCT04226547", "title": "Amplatzer Amulet LAAO vs. NOAC", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Atrial Fibrillation", "Stroke", "Bleeding" ], "interventions": [ { "name": "Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder)", "type": "DEVICE" }, { "name": "Non-Vitamin K Oral Antagonists", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Abbott Medical Devices", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2650, "start_date": "2020-07-07", "completion_date": "2031-04", "has_results": false, "last_update_posted_date": "2026-02-10", "last_synced_at": "2026-09-26T12:40:48.092Z", "location_count": 79, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 65 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Jonesboro", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04226547" }, { "nct_id": "NCT02928497", "title": "Assessment of the WATCHMAN™ Device in Patients Unsuitable for Oral Anticoagulation", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Stroke" ], "interventions": [ { "name": "WATCHMAN LAAC Device Implant", "type": "DEVICE" }, { "name": "Single Antiplatelet Therapy or No Therapy (Control)", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Boston Scientific Corporation", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 481, "start_date": "2017-02-06", "completion_date": "2025-09-23", "has_results": true, "last_update_posted_date": "2026-08-25", "last_synced_at": "2026-09-26T12:40:48.092Z", "location_count": 71, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 65 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Jonesboro", "state": "Arkansas" }, { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02928497" }, { "nct_id": "NCT04502017", "title": "Efficacy of Different Anti-Thrombotic Strategies on Device-Related Thrombosis Prevention After Percutaneous Left Atrial Appendage Occlusion", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Device-Related Thrombosis", "Atrial Fibrillation", "Left Atrial Appendage Occlusion" ], "interventions": [ { "name": "ASA plus Clopidogrel", "type": "DRUG" }, { "name": "Genetic-Tailored AntiThrombotic Strategy", "type": "DRUG" }, { "name": "Half-Dose of novel OAC", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Texas Cardiac Arrhythmia Research Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 360, "start_date": "2020-08-05", "completion_date": "2023-12-31", "has_results": false, "last_update_posted_date": "2020-08-07", "last_synced_at": "2026-09-26T12:40:48.092Z", "location_count": 1, "location_summary": "Austin, Texas", "locations": [ { "city": "Austin", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04502017" }, { "nct_id": "NCT06061757", "title": "Use of 4D-ICE in Conjunction With TEE for Left Atrial Appendage Closure", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Atrial Fibrillation", "Stroke" ], "interventions": [ { "name": "Imaging guidance with TEE and ICE for Left atrial appendage closure", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Kansas City Heart Rhythm Research Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 52, "start_date": "2023-05-10", "completion_date": "2025-12-31", "has_results": false, "last_update_posted_date": "2025-08-28", "last_synced_at": "2026-09-26T12:40:48.092Z", "location_count": 1, "location_summary": "Overland Park, Kansas", "locations": [ { "city": "Overland Park", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06061757" }, { "nct_id": "NCT02348515", "title": "Cardiovascular Disease Protection Tissue", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Myocardial Ischemia" ], "interventions": [ { "name": "Heart failure or coronary disease", "type": "PROCEDURE" }, { "name": "Heart transplant patients", "type": "PROCEDURE" }, { "name": "Orthotopic Heart Transplant Patients", "type": "PROCEDURE" }, { "name": "Heart Surgery Patients", "type": "PROCEDURE" }, { "name": "Blood Draw", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 8, "start_date": "2013-06", "completion_date": "2018-09-28", "has_results": false, "last_update_posted_date": "2018-11-27", "last_synced_at": "2026-09-26T12:40:48.092Z", "location_count": 1, "location_summary": "Gainesville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02348515" }, { "nct_id": "NCT06075628", "title": "Long-Term Outcomes of LAA Contrast Flow in CT Scans After Endocardial LAA Closure: The CF-CT Registry", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Atrial Fibrillation", "Ischemic Stroke, Acute" ], "interventions": [ { "name": "Left Atrial Appendage Occlusion", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Kansas City Heart Rhythm Research Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2023-07-24", "completion_date": "2025-12", "has_results": false, "last_update_posted_date": "2025-08-28", "last_synced_at": "2026-09-26T12:40:48.092Z", "location_count": 1, "location_summary": "Overland Park, Kansas", "locations": [ { "city": "Overland Park", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06075628" }, { "nct_id": "NCT07620262", "title": "Prospective Remapping With Concomitant Left Atrial Appendage Occlusion to Ensure Durable Electroporation Study", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Atrial Fibrillation (AF)" ], "interventions": [ { "name": "Remapping Procedure", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Northwell Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 50, "start_date": "2026-05-01", "completion_date": "2028-07", "has_results": false, "last_update_posted_date": "2026-07-17", "last_synced_at": "2026-09-26T12:40:48.092Z", "location_count": 1, "location_summary": "Bay Shore, New York", "locations": [ { "city": "Bay Shore", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07620262" }, { "nct_id": "NCT06436924", "title": "Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Atrial Fibrillation" ], "interventions": [ { "name": "Left Atrial Appendage Device Implant", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Heart Rhythm Clinical and Research Solutions, LLC", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 569, "start_date": "2024-05-14", "completion_date": "2026-03-19", "has_results": false, "last_update_posted_date": "2026-08-26", "last_synced_at": "2026-09-26T12:40:48.092Z", "location_count": 7, "location_summary": "Birmingham, Alabama • Tucson, Arizona • Aurora, Colorado + 4 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Naples", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06436924" } ] }