{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Leg+sham+therapy&page=2",
    "query": {
      "intervention": "Leg sham therapy",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 340,
    "total_pages": 34,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Leg+sham+therapy&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Leg+sham+therapy&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-01T19:09:52.900Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06182397",
      "title": "Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arterial Disease of Legs",
        "Below-the-knee Obstruction",
        "PAD - Peripheral Arterial Disease"
      ],
      "interventions": [
        {
          "name": "MagicTouch PTA Sirolimus drug coated balloon",
          "type": "DEVICE"
        },
        {
          "name": "Placebo balloon angioplasty",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Concept Medical Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 368,
      "start_date": "2025-01-16",
      "completion_date": "2031-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-02",
      "last_synced_at": "2026-10-01T19:09:52.900Z",
      "location_count": 29,
      "location_summary": "Scottsdale, Arizona • Los Angeles, California • Clearwater, Florida + 22 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Clearwater",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06182397"
    },
    {
      "nct_id": "NCT00058968",
      "title": "A Study for the Treatment of Painful Diabetic Neuropathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diabetic Neuropathy, Painful"
      ],
      "interventions": [
        {
          "name": "Duloxetine hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eli Lilly and Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 660,
      "start_date": "2002-10",
      "completion_date": "2005-03",
      "has_results": false,
      "last_update_posted_date": "2007-05-17",
      "last_synced_at": "2026-10-01T19:09:52.900Z",
      "location_count": 1,
      "location_summary": "Pembroke Pines, Florida",
      "locations": [
        {
          "city": "Pembroke Pines",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00058968"
    },
    {
      "nct_id": "NCT05036213",
      "title": "The Effects of Oral Inorganic Nitrate Supplementation on Lower Limb Perfusion During Exercise in Patients With PAD",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Peripheral Arterial Disease",
        "Peripheral Vascular Diseases"
      ],
      "interventions": [
        {
          "name": "BEET IT - Concentrate Beet root juice",
          "type": "DRUG"
        },
        {
          "name": "BEET IT - Concentrate Beet root juice (nitrate depleted)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 28,
      "start_date": "2020-02-01",
      "completion_date": "2024-12",
      "has_results": false,
      "last_update_posted_date": "2023-11-29",
      "last_synced_at": "2026-10-01T19:09:52.900Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05036213"
    },
    {
      "nct_id": "NCT02130310",
      "title": "Evaluation of CureXcell® in Treating Chronic Venous Leg Ulcers",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Venous Leg Ulcers"
      ],
      "interventions": [
        {
          "name": "CureXcell®",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo injection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Macrocure Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 252,
      "start_date": "2014-05",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2015-09-23",
      "last_synced_at": "2026-10-01T19:09:52.900Z",
      "location_count": 28,
      "location_summary": "Mesa, Arizona • Phoenix, Arizona • Carlsbad, California + 25 more",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Carlsbad",
          "state": "California"
        },
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02130310"
    },
    {
      "nct_id": "NCT00256854",
      "title": "Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Restless Legs Syndrome",
        "Restless Legs Syndrome (RLS)"
      ],
      "interventions": [
        {
          "name": "Ropinirole IR 1 mg",
          "type": "DRUG"
        },
        {
          "name": "Ropinirole IR 2 mg",
          "type": "DRUG"
        },
        {
          "name": "Ropinirole IR 1 mg Placebo",
          "type": "DRUG"
        },
        {
          "name": "Ropinirole IR 2 mg Placebo",
          "type": "DRUG"
        },
        {
          "name": "Ropinirole CR 2 mg",
          "type": "DRUG"
        },
        {
          "name": "Ropinirole CR 3 mg",
          "type": "DRUG"
        },
        {
          "name": "Ropinirole CR 2 mg Placebo",
          "type": "DRUG"
        },
        {
          "name": "Ropinirole CR 3 mg Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 135,
      "start_date": "2005-11-14",
      "completion_date": "2006-09-21",
      "has_results": true,
      "last_update_posted_date": "2019-03-15",
      "last_synced_at": "2026-10-01T19:09:52.900Z",
      "location_count": 30,
      "location_summary": "Laguna Hills, California • Oxnard, California • Pasadena, California + 27 more",
      "locations": [
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Oxnard",
          "state": "California"
        },
        {
          "city": "Pasadena",
          "state": "California"
        },
        {
          "city": "Reseda",
          "state": "California"
        },
        {
          "city": "Boca Raton",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00256854"
    },
    {
      "nct_id": "NCT00584246",
      "title": "Pregabalin (Lyrica) for the Treatment of Restless Legs Syndrome",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Restless Legs Syndrome"
      ],
      "interventions": [
        {
          "name": "Pregabalin (Lyrica)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2007-11",
      "completion_date": "2008-05",
      "has_results": false,
      "last_update_posted_date": "2021-11-16",
      "last_synced_at": "2026-10-01T19:09:52.900Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00584246"
    },
    {
      "nct_id": "NCT00668434",
      "title": "Effectiveness of Oral Prednisone in Improving Physical Functioning and Decreasing Pain in People With Sciatica",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Sciatica"
      ],
      "interventions": [
        {
          "name": "Prednisone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 269,
      "start_date": "2008-11",
      "completion_date": "2013-09",
      "has_results": true,
      "last_update_posted_date": "2015-04-28",
      "last_synced_at": "2026-10-01T19:09:52.900Z",
      "location_count": 3,
      "location_summary": "Redwood City, California • Roseville, California • San Jose, California",
      "locations": [
        {
          "city": "Redwood City",
          "state": "California"
        },
        {
          "city": "Roseville",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00668434"
    },
    {
      "nct_id": "NCT04733287",
      "title": "Heat Therapy and Muscle Function Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exercise Intolerance",
        "Aging",
        "Heat Therapy",
        "High Intensity Interval Training"
      ],
      "interventions": [
        {
          "name": "High Intensity Interval Training of the Knee Extensors",
          "type": "OTHER"
        },
        {
          "name": "Muscle Heat Therapy",
          "type": "OTHER"
        },
        {
          "name": "Muscle Disuse",
          "type": "OTHER"
        },
        {
          "name": "Sham Heat Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham Young University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 148,
      "start_date": "2021-04-01",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-02-02",
      "last_synced_at": "2026-10-01T19:09:52.900Z",
      "location_count": 1,
      "location_summary": "Provo, Utah",
      "locations": [
        {
          "city": "Provo",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04733287"
    },
    {
      "nct_id": "NCT07652944",
      "title": "Trial to Test the Efficacy of Using Magnetic Fields to Stimulate the Back to Treat Chronic Lower Back Pain.",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lower Back Pain Chronic"
      ],
      "interventions": [
        {
          "name": "peripheral magnetic stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Home exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Joe X. Zhang",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 88,
      "start_date": "2026-07",
      "completion_date": "2027-02",
      "has_results": false,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-10-01T19:09:52.900Z",
      "location_count": 1,
      "location_summary": "Edwards Air Force Base, California",
      "locations": [
        {
          "city": "Edwards Air Force Base",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07652944"
    },
    {
      "nct_id": "NCT02553733",
      "title": "Effect of Beetroot Juice on Coronary Blood Flow and Walking Performance in PAD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Peripheral Arterial Disease"
      ],
      "interventions": [
        {
          "name": "Beetroot juice",
          "type": "DRUG"
        },
        {
          "name": "Beetroot juice placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "David N. Proctor, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 11,
      "start_date": "2015-12",
      "completion_date": "2020-02",
      "has_results": true,
      "last_update_posted_date": "2026-08-13",
      "last_synced_at": "2026-10-01T19:09:52.900Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02553733"
    }
  ]
}