{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lemborexant+10+MG", "query": { "intervention": "Lemborexant 10 MG" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 19, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lemborexant+10+MG&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-21T20:29:57.540Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06981195", "title": "Effects of Lemborexant on Insomnia and Its Relationship to Mood and Behavior on Opioid Use Disorder Subjects", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Opioid Use Disorder", "Opioid Use", "Insomnia", "Orexin Antagonist" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Lemborexant 10 MG", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Virginia Commonwealth University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2025-05-27", "completion_date": "2029-07-30", "has_results": false, "last_update_posted_date": "2026-07-09", "last_synced_at": "2026-09-21T20:29:57.540Z", "location_count": 1, "location_summary": "Richmond, Virginia", "locations": [ { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT06981195" }, { "nct_id": "NCT02350309", "title": "Study to Evaluate the Effect of 2 Dosage Strengths of Lemborexant (E2006) on a Multiple Sleep Latency Test in Participants With Insomnia Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Insomnia Disorder" ], "interventions": [ { "name": "Lemborexant 5 mg", "type": "DRUG" }, { "name": "Lemborexant 10 mg", "type": "DRUG" }, { "name": "Lemborexant-matched placebo.", "type": "DRUG" }, { "name": "Flurazepam 30 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eisai Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 69, "start_date": "2014-12-13", "completion_date": "2015-04-21", "has_results": true, "last_update_posted_date": "2020-01-18", "last_synced_at": "2026-09-21T20:29:57.540Z", "location_count": 2, "location_summary": "Atlanta, Georgia • Crestview Hills, Kentucky", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Crestview Hills", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT02350309" }, { "nct_id": "NCT03471871", "title": "Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Healthy Subjects and Adult and Elderly Subjects With Mild Obstructive Sleep Apnea", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Obstructive Sleep Apnea", "Healthy Subjects" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Lemborexant 10 mg", "type": "DRUG" }, { "name": "Lemborexant 25 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eisai Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 146, "start_date": "2018-02-21", "completion_date": "2018-08-03", "has_results": true, "last_update_posted_date": "2020-02-17", "last_synced_at": "2026-09-21T20:29:57.540Z", "location_count": 11, "location_summary": "Glendale, Arizona • Phoenix, Arizona • San Diego, California + 7 more", "locations": [ { "city": "Glendale", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "San Diego", "state": "California" }, { "city": "Brandon", "state": "Florida" }, { "city": "Hollywood", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03471871" }, { "nct_id": "NCT01463098", "title": "A 2-Part Single Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Insomnia" ], "interventions": [ { "name": "E2006 1.0 mg", "type": "DRUG" }, { "name": "E2006 2.5 mg", "type": "DRUG" }, { "name": "E2006 5.0 mg", "type": "DRUG" }, { "name": "E2006 10.0 mg", "type": "DRUG" }, { "name": "E2006 25.0 mg", "type": "DRUG" }, { "name": "E2006 50.0 mg", "type": "DRUG" }, { "name": "E2006 100 mg", "type": "DRUG" }, { "name": "E2006 200 mg", "type": "DRUG" }, { "name": "Zolpidem 10 mg", "type": "DRUG" }, { "name": "E2006 Matched Placebo or Zolpidem Matched Placebo", "type": "DRUG" }, { "name": "E2006 Matched Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eisai Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "18 Years to 64 Years" }, "enrollment_count": 122, "start_date": "2011-10-05", "completion_date": "2012-08-11", "has_results": true, "last_update_posted_date": "2020-01-18", "last_synced_at": "2026-09-21T20:29:57.540Z", "location_count": 2, "location_summary": "New York, New York • Cincinnati, Ohio", "locations": [ { "city": "New York", "state": "New York" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01463098" }, { "nct_id": "NCT03451110", "title": "Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Contraceptive, Famotidine, or Fluconazole in Healthy Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Subjects" ], "interventions": [ { "name": "lemborexant", "type": "DRUG" }, { "name": "Loestrin", "type": "DRUG" }, { "name": "famotidine", "type": "DRUG" }, { "name": "fluconazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eisai Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 50, "start_date": "2018-02-05", "completion_date": "2018-03-23", "has_results": false, "last_update_posted_date": "2018-09-06", "last_synced_at": "2026-09-21T20:29:57.540Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03451110" }, { "nct_id": "NCT03440424", "title": "Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Mild and Moderate Hepatic Impairment Compared to Healthy Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Hepatic Impairment" ], "interventions": [ { "name": "Lemborexant", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eisai Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "18 Years to 79 Years" }, "enrollment_count": 24, "start_date": "2018-01-26", "completion_date": "2018-04-23", "has_results": true, "last_update_posted_date": "2020-03-20", "last_synced_at": "2026-09-21T20:29:57.540Z", "location_count": 2, "location_summary": "Miami, Florida • Orlando, Florida", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03440424" }, { "nct_id": "NCT05458609", "title": "Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Alcohol Use Disorder" ], "interventions": [ { "name": "Lemborexant 10 mg", "type": "DRUG" }, { "name": "Naltrexone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Baylor College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 8, "start_date": "2023-02-09", "completion_date": "2024-01-30", "has_results": true, "last_update_posted_date": "2026-03-24", "last_synced_at": "2026-09-21T20:29:57.540Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05458609" }, { "nct_id": "NCT05463861", "title": "Lemborexant in Delayed Sleep Phase Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Delayed Sleep Phase Syndrome" ], "interventions": [ { "name": "Lemborexant", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 71, "start_date": "2022-02-01", "completion_date": "2026-01-21", "has_results": false, "last_update_posted_date": "2026-03-02", "last_synced_at": "2026-09-21T20:29:57.540Z", "location_count": 1, "location_summary": "Redwood City, California", "locations": [ { "city": "Redwood City", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05463861" }, { "nct_id": "NCT04647383", "title": "A Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Participants With Moderate to Severe Obstructive Sleep Apnea, and in Adult and Elderly Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Sleep Apnea, Obstructive", "Pulmonary Disease, Chronic Obstructive", "Respiration Disorders" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Lemborexant 10 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eisai Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "45 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "45 Years to 90 Years" }, "enrollment_count": 63, "start_date": "2021-01-06", "completion_date": "2022-02-10", "has_results": true, "last_update_posted_date": "2023-10-10", "last_synced_at": "2026-09-21T20:29:57.540Z", "location_count": 11, "location_summary": "Glendale, Arizona • San Diego, California • Brandon, Florida + 7 more", "locations": [ { "city": "Glendale", "state": "Arizona" }, { "city": "San Diego", "state": "California" }, { "city": "Brandon", "state": "Florida" }, { "city": "Clearwater", "state": "Florida" }, { "city": "Hollywood", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04647383" }, { "nct_id": "NCT04009577", "title": "A Study to Evaluate Next-Dose Transition From Zolpidem to Lemborexant (LEM) for the Treatment of Insomnia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Insomnia" ], "interventions": [ { "name": "LEM 5 mg", "type": "DRUG" }, { "name": "LEM 10 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eisai Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 53, "start_date": "2019-07-15", "completion_date": "2020-06-26", "has_results": true, "last_update_posted_date": "2021-04-12", "last_synced_at": "2026-09-21T20:29:57.540Z", "location_count": 17, "location_summary": "Glendale, Arizona • Sacramento, California • San Diego, California + 14 more", "locations": [ { "city": "Glendale", "state": "Arizona" }, { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Santa Ana", "state": "California" }, { "city": "Fleming Island", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04009577" } ] }