{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Letter+Intervention",
    "query": {
      "intervention": "Letter Intervention"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 261,
    "total_pages": 27,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Letter+Intervention&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-09T12:53:00.817Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04145934",
      "title": "A Randomized Controlled Trial of a Multicomponent Walking Aid Program for People With MS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "ADSTEP",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 78,
      "start_date": "2020-02-06",
      "completion_date": "2023-01-26",
      "has_results": false,
      "last_update_posted_date": "2023-03-23",
      "last_synced_at": "2026-10-09T12:53:00.817Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04145934"
    },
    {
      "nct_id": "NCT03527550",
      "title": "Cognitive Control Training for Urgency in a Naturalistic Clinical Setting",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Impulsive Behavior",
        "Mental Disorders"
      ],
      "interventions": [
        {
          "name": "Cognitive Control Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mclean Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2018-09-11",
      "completion_date": "2020-03-11",
      "has_results": true,
      "last_update_posted_date": "2021-08-20",
      "last_synced_at": "2026-10-09T12:53:00.817Z",
      "location_count": 1,
      "location_summary": "Belmont, Massachusetts",
      "locations": [
        {
          "city": "Belmont",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03527550"
    },
    {
      "nct_id": "NCT01515943",
      "title": "Convergence Insufficiency Treatment Study (CITS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Convergence Insufficiency"
      ],
      "interventions": [
        {
          "name": "Active home-based computer vergence/accommodative therapy",
          "type": "OTHER"
        },
        {
          "name": "Near target push-ups",
          "type": "PROCEDURE"
        },
        {
          "name": "Placebo home-based computer vergence/accommodative therapy",
          "type": "OTHER"
        },
        {
          "name": "Placebo yoked prism flippers",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "9 Years to 17 Years"
      },
      "enrollment_count": 204,
      "start_date": "2012-06",
      "completion_date": "2015-01",
      "has_results": true,
      "last_update_posted_date": "2017-04-12",
      "last_synced_at": "2026-10-09T12:53:00.817Z",
      "location_count": 2,
      "location_summary": "Cranberry TWP, Pennsylvania • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Cranberry TWP",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01515943"
    },
    {
      "nct_id": "NCT00766766",
      "title": "Reduction of Environmental Tobacco Smoke (ETS) Exposure In Pediatric Cancer Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Health Risk and Behavioral Skills Coaching Sessions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Telephone Coaching Sessions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Physician Feedback Letter",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": 166,
      "start_date": "2002-09",
      "completion_date": "2010-06",
      "has_results": false,
      "last_update_posted_date": "2013-09-06",
      "last_synced_at": "2026-10-09T12:53:00.817Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00766766"
    },
    {
      "nct_id": "NCT07384156",
      "title": "Enhancing Orthographic Communication and Literacy Outcomes for AAC Learners",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Literacy",
        "Communication, Nonverbal"
      ],
      "interventions": [
        {
          "name": "ALLSTAR",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "5 Years to 12 Years"
      },
      "enrollment_count": 60,
      "start_date": "2026-03-01",
      "completion_date": "2031-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-02-03",
      "last_synced_at": "2026-10-09T12:53:00.817Z",
      "location_count": 1,
      "location_summary": "State College, Pennsylvania",
      "locations": [
        {
          "city": "State College",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07384156"
    },
    {
      "nct_id": "NCT03146078",
      "title": "Rate of Progression in USH2A-related Retinal Degeneration",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Usher Syndrome, Type 2A",
        "Retinitis Pigmentosa 39"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "8 Years and older"
      },
      "enrollment_count": 127,
      "start_date": "2017-08-11",
      "completion_date": "2029-12-15",
      "has_results": false,
      "last_update_posted_date": "2026-07-23",
      "last_synced_at": "2026-10-09T12:53:00.817Z",
      "location_count": 9,
      "location_summary": "San Francisco, California • Gainesville, Florida • Baltimore, Maryland + 6 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03146078"
    },
    {
      "nct_id": "NCT05216458",
      "title": "Using Personalized Letters and Emails to Increase Health Insurance Take-up and Improve Plan Choice Quality",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Health Behavior"
      ],
      "interventions": [
        {
          "name": "Emails and letter intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control group",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Office of Evaluation Sciences",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 44000,
      "start_date": "2021-05-27",
      "completion_date": "2021-08-31",
      "has_results": false,
      "last_update_posted_date": "2022-01-31",
      "last_synced_at": "2026-10-09T12:53:00.817Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05216458"
    },
    {
      "nct_id": "NCT03278990",
      "title": "Scalable Interventions to Increase PrEP Adherence: Value Affirmation and Future Selves",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Prevention"
      ],
      "interventions": [
        {
          "name": "Value Affirmation and Future Selves Combination",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control writing exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stuart Fisk",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 26,
      "start_date": "2018-12-19",
      "completion_date": "2020-12-16",
      "has_results": false,
      "last_update_posted_date": "2021-10-11",
      "last_synced_at": "2026-10-09T12:53:00.817Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03278990"
    },
    {
      "nct_id": "NCT02360605",
      "title": "Health Literacy Interventions to Overcome Disparities in CRC Screening",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colorectal Cancer"
      ],
      "interventions": [
        {
          "name": "automated telephone reminder",
          "type": "BEHAVIORAL"
        },
        {
          "name": "prevention coordinator",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health literacy appropriate education and demonstration",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Louisiana State University Health Sciences Center Shreveport",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 620,
      "start_date": "2015-02",
      "completion_date": "2018-11-06",
      "has_results": true,
      "last_update_posted_date": "2021-06-30",
      "last_synced_at": "2026-10-09T12:53:00.817Z",
      "location_count": 1,
      "location_summary": "Shreveport, Louisiana",
      "locations": [
        {
          "city": "Shreveport",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02360605"
    },
    {
      "nct_id": "NCT04758637",
      "title": "AESOPS Trial 2 (AESOPS-2): Availability of Opioid Harm",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Abuse"
      ],
      "interventions": [
        {
          "name": "Overdose Notification",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 61,
      "start_date": "2023-01-23",
      "completion_date": "2024-03-18",
      "has_results": true,
      "last_update_posted_date": "2025-10-07",
      "last_synced_at": "2026-10-09T12:53:00.817Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04758637"
    }
  ]
}