{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Levodopa%2FCarbidopa+%284%3A1%29", "query": { "intervention": "Levodopa/Carbidopa (4:1)" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 24, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Levodopa%2FCarbidopa+%284%3A1%29&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-02T15:26:18.530Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06219915", "title": "Neurobiological Drivers of Mobility Resilience: The Dopaminergic System - Placebo-Controlled Arm", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Parkinsonian Signs in Older Persons" ], "interventions": [ { "name": "Carbidopa 25 mg", "type": "DRUG" }, { "name": "Carbidopa-Levodopa 25/100 mg", "type": "DRUG" }, { "name": "Placebo 1", "type": "DRUG" }, { "name": "Placebo 2", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 13, "start_date": "2024-03-15", "completion_date": "2024-05-30", "has_results": true, "last_update_posted_date": "2025-06-17", "last_synced_at": "2026-10-02T15:26:18.530Z", "location_count": 2, "location_summary": "Ann Arbor, Michigan", "locations": [ { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT06219915" }, { "nct_id": "NCT01281475", "title": "A Trial of Levodopa in Angelman Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Angelman Syndrome" ], "interventions": [ { "name": "Levodopa", "type": "DRUG" }, { "name": "Placebo Oral Capsule", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Wen-Hann Tan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": "12 Years", "sex": "ALL", "summary": "4 Years to 12 Years" }, "enrollment_count": 67, "start_date": "2011-01", "completion_date": "2015-07", "has_results": true, "last_update_posted_date": "2020-07-15", "last_synced_at": "2026-10-02T15:26:18.530Z", "location_count": 7, "location_summary": "San Diego, California • San Francisco, California • Boston, Massachusetts + 4 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "Greenwood", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01281475" }, { "nct_id": "NCT00880620", "title": "A Study To Evaluate The Safety And Efficacy Of IPX066 In Subjects With Parkinson's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Parkinson's Disease" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "IPX066 95 mg LD", "type": "DRUG" }, { "name": "IPX066 145 mg LD", "type": "DRUG" }, { "name": "IPX066 195 mg LD", "type": "DRUG" }, { "name": "IPX066 245 mg LD", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Impax Laboratories, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 381, "start_date": "2009-04", "completion_date": "2010-11", "has_results": true, "last_update_posted_date": "2019-10-29", "last_synced_at": "2026-10-02T15:26:18.530Z", "location_count": 27, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Garden Grove, California + 22 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Garden Grove", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00880620" }, { "nct_id": "NCT03000569", "title": "A Study to Evaluate SAGE-217 in Participants With Parkinson's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Parkinson Disease" ], "interventions": [ { "name": "SAGE-217", "type": "DRUG" }, { "name": "Levodopa", "type": "DRUG" }, { "name": "Antiparkinsonian Agent(s)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "40 Years to 75 Years" }, "enrollment_count": 29, "start_date": "2016-11-30", "completion_date": "2017-09-11", "has_results": true, "last_update_posted_date": "2023-11-29", "last_synced_at": "2026-10-02T15:26:18.530Z", "location_count": 11, "location_summary": "Panorama City, California • Jacksonville, Florida • Miami, Florida + 7 more", "locations": [ { "city": "Panorama City", "state": "California" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03000569" }, { "nct_id": "NCT06075771", "title": "Dopaminergic Therapy for Anhedonia - 2", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Anhedonia", "Depression" ], "interventions": [ { "name": "Carbidopa Levodopa", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "25 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "25 Years to 55 Years" }, "enrollment_count": 70, "start_date": "2023-11-21", "completion_date": "2027-01", "has_results": false, "last_update_posted_date": "2026-01-28", "last_synced_at": "2026-10-02T15:26:18.530Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT06075771" }, { "nct_id": "NCT03670953", "title": "A Study to Evaluate the Safety and Efficacy of IPX203 in Parkinson's Disease Participants With Motor Fluctuations", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Parkinson's Disease (Disorder)" ], "interventions": [ { "name": "IR CD-LD", "type": "DRUG" }, { "name": "IPX203 ER CD-LD", "type": "DRUG" }, { "name": "Placebo Matching IPX203", "type": "OTHER" }, { "name": "Placebo Matching IR CD-LD", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Impax Laboratories, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 630, "start_date": "2018-11-06", "completion_date": "2021-06-15", "has_results": true, "last_update_posted_date": "2023-02-09", "last_synced_at": "2026-10-02T15:26:18.530Z", "location_count": 56, "location_summary": "Phoenix, Arizona • Little Rock, Arkansas • Loma Linda, California + 46 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Loma Linda", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03670953" }, { "nct_id": "NCT04723147", "title": "DTA (Dopaminergic Therapy for Anhedonia) Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Depression", "Anhedonia" ], "interventions": [ { "name": "Carbidopa Levodopa", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "25 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "25 Years to 55 Years" }, "enrollment_count": 19, "start_date": "2021-01-29", "completion_date": "2023-10-11", "has_results": true, "last_update_posted_date": "2024-12-16", "last_synced_at": "2026-10-02T15:26:18.530Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04723147" }, { "nct_id": "NCT04006210", "title": "Efficacy, Safety and Tolerability Study of ND0612 vs. Oral Immediate Release Levodopa/Carbidopa (IR-LD/CD) in Subjects With Parkinson's Disease Experiencing Motor Fluctuations", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Parkinson's Disease" ], "interventions": [ { "name": "ND0612 Solution for SC infusion", "type": "COMBINATION_PRODUCT" }, { "name": "Placebo for SC infusion", "type": "COMBINATION_PRODUCT" }, { "name": "Oral IR-LD/CD", "type": "DRUG" }, { "name": "Placebo for Oral IR-LD/CD", "type": "DRUG" } ], "intervention_types": [ "COMBINATION_PRODUCT", "DRUG" ], "sponsor": "NeuroDerm Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 381, "start_date": "2019-09-30", "completion_date": "2027-02", "has_results": false, "last_update_posted_date": "2025-05-21", "last_synced_at": "2026-10-02T15:26:18.530Z", "location_count": 38, "location_summary": "Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 34 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Los Angeles", "state": "California" }, { "city": "Reseda", "state": "California" }, { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04006210" }, { "nct_id": "NCT02633007", "title": "A Study of the Safety and Pharmacokinetics of Levodopa Following Administration of CVT 301 (Levodopa Inhalation Powder) in Adults With Asthma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Asthma" ], "interventions": [ { "name": "CVT-301 (levodopa inhalation powder)", "type": "DRUG" }, { "name": "Carbidopa", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Acorda Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "25 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "25 Years to 65 Years" }, "enrollment_count": 25, "start_date": "2015-12", "completion_date": "2016-05", "has_results": false, "last_update_posted_date": "2016-06-13", "last_synced_at": "2026-10-02T15:26:18.530Z", "location_count": 3, "location_summary": "Daytona Beach, Florida • North Dartmouth, Massachusetts • Dallas, Texas", "locations": [ { "city": "Daytona Beach", "state": "Florida" }, { "city": "North Dartmouth", "state": "Massachusetts" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02633007" }, { "nct_id": "NCT04821830", "title": "Vigor and the LDR in Parkinson Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Parkinson Disease" ], "interventions": [ { "name": "carbidopa/levodopa, as prescribed by treating physician", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "45 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "45 Years to 90 Years" }, "enrollment_count": 19, "start_date": "2020-02-12", "completion_date": "2024-04-25", "has_results": true, "last_update_posted_date": "2025-07-18", "last_synced_at": "2026-10-02T15:26:18.530Z", "location_count": 1, "location_summary": "Ann Arbor, Michigan", "locations": [ { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT04821830" } ] }