{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Levonorgestrel+IUS",
    "query": {
      "intervention": "Levonorgestrel IUS"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 25,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Levonorgestrel+IUS&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-09T20:01:08.781Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00528112",
      "title": "Levonorgestrel Contraceptive Intrauterine Systems (LCS) Pearl Index Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Contraception"
      ],
      "interventions": [
        {
          "name": "LCS12",
          "type": "DRUG"
        },
        {
          "name": "LCS16",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 35 Years · Female only"
      },
      "enrollment_count": 2885,
      "start_date": "2007-08",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2017-01-25",
      "last_synced_at": "2026-09-09T20:01:08.781Z",
      "location_count": 57,
      "location_summary": "Mobile, Alabama • Glendale, Arizona • Phoenix, Arizona + 47 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Carmichael",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00528112"
    },
    {
      "nct_id": "NCT02456584",
      "title": "Pharmacodynamics and Pharmacokinetics Study of Existing DMPA Contraceptive Methods",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Contraception"
      ],
      "interventions": [
        {
          "name": "DMPA 150",
          "type": "DRUG"
        },
        {
          "name": "DMPA 300",
          "type": "DRUG"
        },
        {
          "name": "DMPA 104",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "FHI 360",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 42,
      "start_date": "2015-09",
      "completion_date": "2018-08-30",
      "has_results": false,
      "last_update_posted_date": "2018-10-18",
      "last_synced_at": "2026-09-09T20:01:08.781Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02456584"
    },
    {
      "nct_id": "NCT01594476",
      "title": "Early Postpartum Intrauterine Device (IUD) Placement",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Contraception"
      ],
      "interventions": [
        {
          "name": "Levonorgestrel IUS",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 201,
      "start_date": "2012-03",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2019-01-11",
      "last_synced_at": "2026-09-09T20:01:08.781Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01594476"
    },
    {
      "nct_id": "NCT03182140",
      "title": "KYleena Satisfaction Study / Observational Study on User Satisfaction With the Levonorgestrel Intrauterine Delivery System Kyleena (LNG-IUS 12) in New Contraceptive Users and After Switching From Another Contraceptive Method",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Contraception"
      ],
      "interventions": [
        {
          "name": "Kyleena",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 1134,
      "start_date": "2017-07-06",
      "completion_date": "2020-03-31",
      "has_results": false,
      "last_update_posted_date": "2021-03-29",
      "last_synced_at": "2026-09-09T20:01:08.781Z",
      "location_count": 12,
      "location_summary": "Lakewood, Colorado • Sarasota, Florida • Wellington, Florida + 9 more",
      "locations": [
        {
          "city": "Lakewood",
          "state": "Colorado"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Wellington",
          "state": "Florida"
        },
        {
          "city": "Fall River",
          "state": "Massachusetts"
        },
        {
          "city": "Saginaw",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03182140"
    },
    {
      "nct_id": "NCT00621543",
      "title": "Insertion of an Intrauterine Device (IUD) After Medical Abortion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intrauterine Device Expulsion",
        "Medical Abortion",
        "Induced Abortion"
      ],
      "interventions": [
        {
          "name": "IUD insertion [Copper T-380A or Levonorgestrel (intrauterine system) IUS]",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 64 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2006-03",
      "completion_date": "2008-09",
      "has_results": true,
      "last_update_posted_date": "2011-07-14",
      "last_synced_at": "2026-09-09T20:01:08.781Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00621543"
    },
    {
      "nct_id": "NCT02362373",
      "title": "Women With Epilepsy: a Pilot Study of PK and PD Anti-epileptic Drug Effects in Levonorgestrel Intrauterine System Users",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Epilepsy",
        "Contraception"
      ],
      "interventions": [
        {
          "name": "levonorgestrel IUS",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 20,
      "start_date": "2011-08",
      "completion_date": "2014-01",
      "has_results": true,
      "last_update_posted_date": "2016-01-18",
      "last_synced_at": "2026-09-09T20:01:08.781Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02362373"
    },
    {
      "nct_id": "NCT02121067",
      "title": "LNG-IUS at 2 Weeks Postpartum",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Contraception",
        "Malposition of Intrauterine Contraceptive Device"
      ],
      "interventions": [
        {
          "name": "Levonorgestrel Intrauterine System (LNG-IUS)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 50,
      "start_date": "2014-09",
      "completion_date": "2016-06",
      "has_results": true,
      "last_update_posted_date": "2017-08-24",
      "last_synced_at": "2026-09-09T20:01:08.781Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02121067"
    },
    {
      "nct_id": "NCT00360490",
      "title": "Study in Women With Idiopathic Menorrhagia to Determine the Reduction in Menstrual Blood Loss (MBL) After Treatment With the Levonorgestrel-releasing Intrauterine System (IUS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Menorrhagia"
      ],
      "interventions": [
        {
          "name": "Levonorgestrel IUS (Mirena, BAY86-5028)",
          "type": "DRUG"
        },
        {
          "name": "Medroxyprogesterone acetate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 165,
      "start_date": "2006-07",
      "completion_date": "2008-06",
      "has_results": true,
      "last_update_posted_date": "2013-12-09",
      "last_synced_at": "2026-09-09T20:01:08.781Z",
      "location_count": 37,
      "location_summary": "Tucson, Arizona • Beverly Hills, California • Carmichael, California + 32 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Carmichael",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00360490"
    },
    {
      "nct_id": "NCT01539720",
      "title": "Levonorgestrel Intrauterine System For Emergency Contraception",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pregnancy, Unplanned",
        "Pregnancy; Accident"
      ],
      "interventions": [
        {
          "name": "Ulipristal acetate",
          "type": "DRUG"
        },
        {
          "name": "levonorgestrel IUS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Planned Parenthood of the St. Louis Region and Southwest Missouri",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "14 Years to 45 Years · Female only"
      },
      "enrollment_count": 274,
      "start_date": "2012-12",
      "completion_date": "2018-11-30",
      "has_results": true,
      "last_update_posted_date": "2024-02-20",
      "last_synced_at": "2026-09-09T20:01:08.781Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Indianapolis, Indiana • St Louis, Missouri",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01539720"
    },
    {
      "nct_id": "NCT01240811",
      "title": "Study of Immune Cell Changes in the Genital Tract 2 Months After Initiation of an IUD for Contraception",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Genital Tract Mucosal Immunity",
        "Genital Tract Microflora"
      ],
      "interventions": [
        {
          "name": "IUD placement",
          "type": "DRUG"
        },
        {
          "name": "Levonorgestrel IUD",
          "type": "DRUG"
        },
        {
          "name": "Copper T380A IUD",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sharon Achilles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 42,
      "start_date": "2010-11",
      "completion_date": "2011-11",
      "has_results": true,
      "last_update_posted_date": "2017-12-26",
      "last_synced_at": "2026-09-09T20:01:08.781Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01240811"
    }
  ]
}