{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lidocaine+Epinephrine%2C+Bupivacaine+Hydrochloride-EPINEPHrine&page=2", "query": { "intervention": "Lidocaine Epinephrine, Bupivacaine Hydrochloride-EPINEPHrine", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 38, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lidocaine+Epinephrine%2C+Bupivacaine+Hydrochloride-EPINEPHrine&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lidocaine+Epinephrine%2C+Bupivacaine+Hydrochloride-EPINEPHrine&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-11T14:21:42.365Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05374499", "title": "Double-Blinded Randomized Controlled Study Investigating the Efficacy of Exparel (Liposomal Bupivacaine) for Postoperative Pain Relief in Mandibular Third Molar Extractions", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Post Operative Pain" ], "interventions": [ { "name": "Liposomal bupivacaine", "type": "DRUG" }, { "name": "0.5% bupivacaine with 1:100,000 epinephrine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Southern California", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "14 Years", "maximum_age": null, "sex": "ALL", "summary": "14 Years and older" }, "enrollment_count": 85, "start_date": "2022-09-01", "completion_date": "2024-05-01", "has_results": true, "last_update_posted_date": "2026-06-04", "last_synced_at": "2026-10-11T14:21:42.365Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05374499" }, { "nct_id": "NCT02678039", "title": "Fluoroscopy-guided Versus Traditional Placement of Epidural Catheters", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pain, Postoperative", "Pain, Chronic" ], "interventions": [ { "name": "Fluoroscopy", "type": "DEVICE" }, { "name": "Traditional", "type": "PROCEDURE" } ], "intervention_types": [ "DEVICE", "PROCEDURE" ], "sponsor": "Dartmouth-Hitchcock Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2012-08", "completion_date": "2014-05", "has_results": true, "last_update_posted_date": "2017-09-12", "last_synced_at": "2026-10-11T14:21:42.365Z", "location_count": 1, "location_summary": "Lebanon, New Hampshire", "locations": [ { "city": "Lebanon", "state": "New Hampshire" } ], "official_url": "https://clinicaltrials.gov/study/NCT02678039" }, { "nct_id": "NCT02726620", "title": "Decision Support for Intraoperative Low Blood Pressure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypotension" ], "interventions": [ { "name": "Attending real-time decision support", "type": "PROCEDURE" }, { "name": "In-room real-time decision support", "type": "PROCEDURE" }, { "name": "Attending feedback emails", "type": "PROCEDURE" }, { "name": "In-room provider feedback emails", "type": "PROCEDURE" }, { "name": "Anesthesia Information Management System (AIMS)", "type": "DEVICE" }, { "name": "Perioperative Data Warehouse (PDW)", "type": "DEVICE" }, { "name": "General anesthesia", "type": "PROCEDURE" }, { "name": "Pager system", "type": "DEVICE" }, { "name": "Central neuraxial anesthesia", "type": "PROCEDURE" }, { "name": "Non-cardiac surgery", "type": "PROCEDURE" }, { "name": "Propofol", "type": "DRUG" }, { "name": "Sevoflurane", "type": "DRUG" }, { "name": "Desflurane", "type": "DRUG" }, { "name": "Isoflurane", "type": "DRUG" }, { "name": "Ephedrine", "type": "DRUG" }, { "name": "Phenylephrine", "type": "DRUG" }, { "name": "Norepinephrine", "type": "DRUG" }, { "name": "Epinephrine", "type": "DRUG" }, { "name": "Dobutamine", "type": "DRUG" }, { "name": "Dopamine", "type": "DRUG" }, { "name": "Isoproterenol", "type": "DRUG" }, { "name": "Milrinone", "type": "DRUG" }, { "name": "Atropine", "type": "DRUG" }, { "name": "Glycopyrrolate", "type": "DRUG" }, { "name": "Vasopressin", "type": "DRUG" }, { "name": "Terlipressin", "type": "DRUG" }, { "name": "Sodium Chloride 0.9%", "type": "DRUG" }, { "name": "Ringer's lactate", "type": "DRUG" }, { "name": "Hydroxyethyl starch solutions", "type": "DRUG" }, { "name": "Fresh Frozen Plasma", "type": "DRUG" }, { "name": "Packed Red Blood Cells", "type": "DRUG" }, { "name": "Albumin solutions", "type": "DRUG" }, { "name": "Plasma-Lyte", "type": "DRUG" }, { "name": "Lidocaine", "type": "DRUG" }, { "name": "Bupivacaine", "type": "DRUG" }, { "name": "Levobupivacaine", "type": "DRUG" }, { "name": "Ropivacaine", "type": "DRUG" }, { "name": "Mepivacaine", "type": "DRUG" }, { "name": "Tetracaine", "type": "DRUG" }, { "name": "Prilocaine", "type": "DRUG" }, { "name": "Procaine", "type": "DRUG" }, { "name": "Chloroprocaine", "type": "DRUG" }, { "name": "Benzocaine", "type": "DRUG" }, { "name": "Articaine", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DEVICE", "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "60 Years to 100 Years" }, "enrollment_count": 22435, "start_date": "2017-01-05", "completion_date": "2018-12-29", "has_results": true, "last_update_posted_date": "2019-05-16", "last_synced_at": "2026-10-11T14:21:42.365Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02726620" }, { "nct_id": "NCT02296099", "title": "Trial Liposomal Bupivacaine Following Retropubic Suburethral Sling for Stress Urinary Incontinence", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Urinary Incontinence, Stress" ], "interventions": [ { "name": "liposomal bupivacaine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "TriHealth Inc.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 114, "start_date": "2014-11", "completion_date": "2016-08", "has_results": true, "last_update_posted_date": "2018-08-16", "last_synced_at": "2026-10-11T14:21:42.365Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02296099" }, { "nct_id": "NCT06189781", "title": "Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cerebral Palsy", "Hip Dysplasia", "Pain, Postoperative" ], "interventions": [ { "name": "Ropivacaine injection", "type": "DRUG" }, { "name": "Bupivacaine, lidocaine, ropivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "18 Years", "sex": "ALL", "summary": "Up to 18 Years" }, "enrollment_count": 90, "start_date": "2023-12-01", "completion_date": "2027-06-30", "has_results": false, "last_update_posted_date": "2024-06-11", "last_synced_at": "2026-10-11T14:21:42.365Z", "location_count": 4, "location_summary": "Los Angeles, California • Santa Monica, California • Chicago, Illinois", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Santa Monica", "state": "California" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT06189781" }, { "nct_id": "NCT01243112", "title": "Effectiveness Study of Different Local Anesthetic Mixtures", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain" ], "interventions": [ { "name": "1% Lidocaine with Epinephrine (1:100,000)", "type": "DRUG" }, { "name": "0.25% Bupivacaine with Epinephrine (1:200,000)", "type": "DRUG" }, { "name": "0.5% Lidocaine, 0.125 Bupivacaine, and epi (1:150,000)", "type": "DRUG" }, { "name": "1% Lidocaine, 0.5% Bupivacaine, and epinephrine (1:150,000)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Scott and White Hospital & Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 25, "start_date": "2010-05", "completion_date": "2010-09", "has_results": true, "last_update_posted_date": "2011-12-02", "last_synced_at": "2026-10-11T14:21:42.365Z", "location_count": 1, "location_summary": "Temple, Texas", "locations": [ { "city": "Temple", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01243112" }, { "nct_id": "NCT03539796", "title": "Epidural Technique: Does it Really Matter to the Patient?", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Anesthesia" ], "interventions": [ { "name": "Dural puncture epidurals (DPE)", "type": "PROCEDURE" }, { "name": "Traditional epidurals (EPI)", "type": "PROCEDURE" }, { "name": "Combined-spinal epidural technique (CSE)", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "FEMALE", "summary": "18 Years to 60 Years · Female only" }, "enrollment_count": 57, "start_date": "2018-05-26", "completion_date": "2022-07-17", "has_results": false, "last_update_posted_date": "2023-01-12", "last_synced_at": "2026-10-11T14:21:42.365Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03539796" }, { "nct_id": "NCT02591888", "title": "Impact of Liposomal Bupivacaine Administered Following Placement of a Transobturator Suburethral Sling", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pain" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Liposomal bupivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "TriHealth Inc.", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 18, "start_date": "2015-02", "completion_date": "2017-12", "has_results": false, "last_update_posted_date": "2018-07-23", "last_synced_at": "2026-10-11T14:21:42.365Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02591888" }, { "nct_id": "NCT03195413", "title": "Early Ultrasound-guided Nerve Block for Painful Hand Injuries in the Emergency Department", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hand Injuries", "Hand Injuries and Disorders" ], "interventions": [ { "name": "Ultrasound-guided forearm nerve block", "type": "PROCEDURE" }, { "name": "1:1 volume measured solution of: 1% lidocaine without epinephrine and 0.5% bupivacaine without epinephrine", "type": "DRUG" }, { "name": "Bedside ultrasound machine", "type": "DEVICE" } ], "intervention_types": [ "PROCEDURE", "DRUG", "DEVICE" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15, "start_date": "2017-07-01", "completion_date": "2018-07-10", "has_results": false, "last_update_posted_date": "2018-10-24", "last_synced_at": "2026-10-11T14:21:42.365Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT03195413" }, { "nct_id": "NCT06547255", "title": "Exparel Versus Bupivacaine in Post-operative Pain Control", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Liposomal Bupivacaine" ], "interventions": [ { "name": "Bupivacaine liposome injectable suspension", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Case Western Reserve University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 100, "start_date": "2024-08-21", "completion_date": "2025-07-01", "has_results": true, "last_update_posted_date": "2026-07-28", "last_synced_at": "2026-10-11T14:21:42.365Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT06547255" } ] }