{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lidocaine+with+epinephrine&page=4",
    "query": {
      "intervention": "Lidocaine with epinephrine",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 164,
    "total_pages": 17,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lidocaine+with+epinephrine&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lidocaine+with+epinephrine&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-10T22:30:35.435Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03913702",
      "title": "Subacromial Methylprednisolone Versus Ketorolac for Shoulder Impingement",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Subacromial Impingement",
        "Subacromial Impingement Syndrome"
      ],
      "interventions": [
        {
          "name": "Ketorolac Tromethamine",
          "type": "DRUG"
        },
        {
          "name": "Methylprednisolone Acetate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 1,
      "start_date": "2019-09-09",
      "completion_date": "2022-11-02",
      "has_results": true,
      "last_update_posted_date": "2025-01-03",
      "last_synced_at": "2026-10-10T22:30:35.435Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03913702"
    },
    {
      "nct_id": "NCT00583011",
      "title": "Local Anesthesia and Pain Perception During an Amniocentesis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pregnancy"
      ],
      "interventions": [
        {
          "name": "Local Anesthesia",
          "type": "DRUG"
        },
        {
          "name": "Placebo Group",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 76,
      "start_date": "2007-10",
      "completion_date": "2011-05",
      "has_results": true,
      "last_update_posted_date": "2021-02-03",
      "last_synced_at": "2026-10-10T22:30:35.435Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00583011"
    },
    {
      "nct_id": "NCT04880707",
      "title": "Twin Block, Pain Medications and Third Molar Extractions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Pain"
      ],
      "interventions": [
        {
          "name": "Twin block local anesthetic nerve block using standard dental anesthetic",
          "type": "DRUG"
        },
        {
          "name": "Twin block with placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2024-03-11",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-22",
      "last_synced_at": "2026-10-10T22:30:35.435Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04880707"
    },
    {
      "nct_id": "NCT05294640",
      "title": "Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Eyelid Tumor",
        "Eyelid Bump",
        "Eyelid Deformity",
        "Eyelid Abscess",
        "Eyelid Boil",
        "Eyelid Papilloma",
        "Anesthesia, Local",
        "Ophthalmology"
      ],
      "interventions": [
        {
          "name": "0.9% Bacteriostatic Local Anesthetic Injection",
          "type": "DRUG"
        },
        {
          "name": "1% Lidocaine with 1:100,000 epinephrine Local Anesthetic Injection",
          "type": "DRUG"
        },
        {
          "name": "Eyelid Lesion Removal",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "18 Years to 110 Years"
      },
      "enrollment_count": 95,
      "start_date": "2022-05-17",
      "completion_date": "2023-02-21",
      "has_results": true,
      "last_update_posted_date": "2025-07-08",
      "last_synced_at": "2026-10-10T22:30:35.435Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05294640"
    },
    {
      "nct_id": "NCT02280291",
      "title": "Single Shot Versus OnQ Pump in Extremity Fractures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain",
        "Fracture"
      ],
      "interventions": [
        {
          "name": "Ankle SSB",
          "type": "DRUG"
        },
        {
          "name": "Ankle OnQ",
          "type": "DRUG"
        },
        {
          "name": "DR SSB",
          "type": "DRUG"
        },
        {
          "name": "DR OnQ",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 100,
      "start_date": "2013-08",
      "completion_date": "2018-12-13",
      "has_results": true,
      "last_update_posted_date": "2020-03-30",
      "last_synced_at": "2026-10-10T22:30:35.435Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02280291"
    },
    {
      "nct_id": "NCT02708433",
      "title": "Clinical Outcomes of Buffered 1% Lidocaine vs. Non-buffered 2% Lidocaine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "Lidocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 23,
      "start_date": "2016-03",
      "completion_date": "2017-09",
      "has_results": true,
      "last_update_posted_date": "2018-09-04",
      "last_synced_at": "2026-10-10T22:30:35.435Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02708433"
    },
    {
      "nct_id": "NCT00889642",
      "title": "Safety and Efficacy Study of an Iontophoretic Patch Containing Lidocaine and Epinephrine for Venipuncture in Healthy Adult Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Local Anesthesia"
      ],
      "interventions": [
        {
          "name": "Iontophoretic Drug Delivery System with Lidocaine/Epinephrine",
          "type": "DEVICE"
        },
        {
          "name": "Iontophoretic Drug Delivery System with Epinephrine",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Dharma Therapeutics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2009-05",
      "completion_date": "2009-06",
      "has_results": false,
      "last_update_posted_date": "2009-06-23",
      "last_synced_at": "2026-10-10T22:30:35.435Z",
      "location_count": 2,
      "location_summary": "Anaheim, California • Overland Park, Missouri",
      "locations": [
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Overland Park",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00889642"
    },
    {
      "nct_id": "NCT07527039",
      "title": "Pectoral Block in Breast Reduction for Pain Control",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Macromastia (Symptomatic)"
      ],
      "interventions": [
        {
          "name": "Pectoral II Nerve Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Post Operative Pain Relievers",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Carilion Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 80,
      "start_date": "2026-04-01",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-10-10T22:30:35.435Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07527039"
    },
    {
      "nct_id": "NCT05507164",
      "title": "Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Occlusion"
      ],
      "interventions": [
        {
          "name": "Temporomasseteric Nerve Block",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 20,
      "start_date": "2022-10-10",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-05",
      "last_synced_at": "2026-10-10T22:30:35.435Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05507164"
    },
    {
      "nct_id": "NCT04369950",
      "title": "Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Physiological Effect of Drugs",
        "Morphine",
        "Analgesics",
        "Analgesics, Opioid",
        "Central Nervous System Depressants",
        "Narcotics"
      ],
      "interventions": [
        {
          "name": "2% lidocaine with 1:200,000 epinephrine and epidural morphine",
          "type": "DRUG"
        },
        {
          "name": "3% 2-chloroprocaine and epidural morphine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 44,
      "start_date": "2020-05-11",
      "completion_date": "2021-07-11",
      "has_results": true,
      "last_update_posted_date": "2022-05-26",
      "last_synced_at": "2026-10-10T22:30:35.435Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04369950"
    }
  ]
}