{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=LipiFlow+treatment",
    "query": {
      "intervention": "LipiFlow treatment"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=LipiFlow+treatment&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T07:45:27.355Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01202747",
      "title": "Evaluation of Screening Methods for Treatment of Meibomian Gland Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Chalazion",
        "Dry Eye Syndromes"
      ],
      "interventions": [
        {
          "name": "LipiFlow System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "TearScience, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2010-09",
      "completion_date": "2011-01",
      "has_results": true,
      "last_update_posted_date": "2011-12-06",
      "last_synced_at": "2026-09-04T07:45:27.355Z",
      "location_count": 3,
      "location_summary": "Hoffman Estates, Illinois • Boston, Massachusetts • Winchester, Massachusetts",
      "locations": [
        {
          "city": "Hoffman Estates",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Winchester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01202747"
    },
    {
      "nct_id": "NCT01521507",
      "title": "Randomized Controlled Trial of Long-term Treatment Effectiveness for Meibomian Gland Dysfunction (MGD) and Dry Eye",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Meibomian Gland Dysfunction",
        "Dry Eye"
      ],
      "interventions": [
        {
          "name": "LipiFlow System",
          "type": "DEVICE"
        },
        {
          "name": "Warm Compress Therapy + Lid Scrub",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "TearScience, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2012-01",
      "completion_date": "2014-01",
      "has_results": true,
      "last_update_posted_date": "2015-02-23",
      "last_synced_at": "2026-09-04T07:45:27.355Z",
      "location_count": 9,
      "location_summary": "Fayetteville, Arkansas • Laguna Hills, California • Miami, Florida + 6 more",
      "locations": [
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Hoffman Estates",
          "state": "Illinois"
        },
        {
          "city": "Lake Villa",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01521507"
    },
    {
      "nct_id": "NCT01808560",
      "title": "Treatment of Meibomian Gland Dysfunction Prior to Cataract Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Blepharitis",
        "Dry Eye Syndrome"
      ],
      "interventions": [
        {
          "name": "LipiFlow Pre-Treatment",
          "type": "DEVICE"
        },
        {
          "name": "LipiFlow Post-treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "TearScience, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "55 Years to 85 Years"
      },
      "enrollment_count": 34,
      "start_date": "2013-03",
      "completion_date": "2015-01",
      "has_results": true,
      "last_update_posted_date": "2018-09-04",
      "last_synced_at": "2026-09-04T07:45:27.355Z",
      "location_count": 7,
      "location_summary": "Hoffman Estates, Illinois • Lake Villa, Illinois • Winchester, Massachusetts + 4 more",
      "locations": [
        {
          "city": "Hoffman Estates",
          "state": "Illinois"
        },
        {
          "city": "Lake Villa",
          "state": "Illinois"
        },
        {
          "city": "Winchester",
          "state": "Massachusetts"
        },
        {
          "city": "Stillwater",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01808560"
    },
    {
      "nct_id": "NCT04413279",
      "title": "Lipiflow Treatment Alone vs. Lipiflow + Dextenza Treatment for Dry Eye Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dry Eye Syndromes"
      ],
      "interventions": [
        {
          "name": "LipiFlow Thermal Pulsation",
          "type": "PROCEDURE"
        },
        {
          "name": "Dexamethasone Intracanalicular Insert, 0.4mg with LipiFlow Thermal Pulsation",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Eye Surgeons of Indiana",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20,
      "start_date": "2020-08-01",
      "completion_date": "2021-07-01",
      "has_results": false,
      "last_update_posted_date": "2022-04-18",
      "last_synced_at": "2026-09-04T07:45:27.355Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04413279"
    },
    {
      "nct_id": "NCT03708367",
      "title": "A Post-Market Evaluation of LipiFlow Treatment in Cataract Surgery Practice",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cataracts",
        "Meibomian Gland Dysfunction (MGD)"
      ],
      "interventions": [
        {
          "name": "LipiFlow Thermal Pulsation System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Surgical Vision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 117,
      "start_date": "2018-10-16",
      "completion_date": "2020-01-13",
      "has_results": true,
      "last_update_posted_date": "2021-04-27",
      "last_synced_at": "2026-09-04T07:45:27.355Z",
      "location_count": 5,
      "location_summary": "Bakersfield, California • Chevy Chase, Maryland • Pennington, New Jersey + 2 more",
      "locations": [
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Chevy Chase",
          "state": "Maryland"
        },
        {
          "city": "Pennington",
          "state": "New Jersey"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Hurst",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03708367"
    },
    {
      "nct_id": "NCT03956225",
      "title": "Comparison Between iLux and LipiFlow in the Treatment of Meibomian Gland Dysfunction (MGD): A 12-month, Multicenter Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Meibomian Gland Dysfunction",
        "Evaporative Dry Eye Disease"
      ],
      "interventions": [
        {
          "name": "Systane iLux® Dry Eye System",
          "type": "DEVICE"
        },
        {
          "name": "LipiFlow® Thermal Pulsation System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 299,
      "start_date": "2019-06-25",
      "completion_date": "2020-10-24",
      "has_results": true,
      "last_update_posted_date": "2021-10-08",
      "last_synced_at": "2026-09-04T07:45:27.355Z",
      "location_count": 15,
      "location_summary": "Long Beach, California • Los Angeles, California • San Diego, California + 12 more",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Panama City",
          "state": "Florida"
        },
        {
          "city": "Highland Park",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03956225"
    },
    {
      "nct_id": "NCT05162261",
      "title": "to Evaluate the Effectiveness and Safety of the Tixel® , VS LipiFlow® in the Treatment of Meibomian Gland Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Meibomian Gland Dysfunction",
        "Dry Eye Syndromes",
        "Dry Eye"
      ],
      "interventions": [
        {
          "name": "Tixel C",
          "type": "DEVICE"
        },
        {
          "name": "LipiFlow",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Novoxel Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 109,
      "start_date": "2022-09-19",
      "completion_date": "2023-09-28",
      "has_results": true,
      "last_update_posted_date": "2025-01-22",
      "last_synced_at": "2026-09-04T07:45:27.355Z",
      "location_count": 5,
      "location_summary": "La Jolla, California • Newport Beach, California • Kansas City, Missouri + 2 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Texas City",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05162261"
    },
    {
      "nct_id": "NCT02102464",
      "title": "Treatment of Meibomian Gland Dysfunction and Dry Eye in Contact Lens Wearers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Meibomian Gland Dysfunction",
        "Dry Eye"
      ],
      "interventions": [
        {
          "name": "LipiFlow treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "TearScience, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 55,
      "start_date": "2014-04",
      "completion_date": "2015-09",
      "has_results": true,
      "last_update_posted_date": "2017-10-18",
      "last_synced_at": "2026-09-04T07:45:27.355Z",
      "location_count": 5,
      "location_summary": "Birmingham, Alabama • Morrow, Georgia • Charlotte, North Carolina + 2 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Morrow",
          "state": "Georgia"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Hanover",
          "state": "Pennsylvania"
        },
        {
          "city": "Kirkland",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02102464"
    },
    {
      "nct_id": "NCT03857919",
      "title": "TearCare System to Treat Dry Eye Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Eye",
        "Meibomian Gland Dysfunction"
      ],
      "interventions": [
        {
          "name": "TearCare",
          "type": "DEVICE"
        },
        {
          "name": "LipiFlow",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sight Sciences, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 235,
      "start_date": "2019-03-03",
      "completion_date": "2020-12-18",
      "has_results": true,
      "last_update_posted_date": "2025-10-01",
      "last_synced_at": "2026-09-04T07:45:27.355Z",
      "location_count": 10,
      "location_summary": "Scottsdale, Arizona • Laguna Hills, California • Newport Beach, California + 7 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Lake Villa",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03857919"
    },
    {
      "nct_id": "NCT04454983",
      "title": "Lipiflow vs iLux Patient Acceptance and Comfort Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Meibomian Gland Dysfunction",
        "Dry Eye"
      ],
      "interventions": [
        {
          "name": "Lipiflow Thermal Pulsation System",
          "type": "DEVICE"
        },
        {
          "name": "iLux System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Epstein, Arthur B., OD, FAAO",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 43,
      "start_date": "2020-01-11",
      "completion_date": "2020-02-29",
      "has_results": false,
      "last_update_posted_date": "2020-08-19",
      "last_synced_at": "2026-09-04T07:45:27.355Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04454983"
    }
  ]
}