{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Listerine+rinse", "query": { "intervention": "Listerine rinse" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 46, "total_pages": 5, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Listerine+rinse&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-12T02:23:17.525Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06010758", "title": "A Two-Week Study of an Anticavity Low pH Mouthwash", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Listerine Experimental Mouthwash", "type": "DRUG" }, { "name": "Colgate Cavity Protection Toothpaste", "type": "DRUG" }, { "name": "Listerine Total Care Zero", "type": "DRUG" }, { "name": "Listerine Cool Mint Zero", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 163, "start_date": "2023-07-17", "completion_date": "2023-08-03", "has_results": false, "last_update_posted_date": "2024-01-12", "last_synced_at": "2026-09-12T02:23:17.525Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT06010758" }, { "nct_id": "NCT07211061", "title": "A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment Methods", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Gingivitis" ], "interventions": [ { "name": "Stannous Fluoride Dentifrice", "type": "DRUG" }, { "name": "Sodium Fluoride Dentifrice", "type": "DRUG" }, { "name": "electric toothbrush", "type": "DEVICE" }, { "name": "Cetylpyridinium Chloride (CPC)", "type": "DRUG" }, { "name": "manual toothbrush", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Procter and Gamble", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 69, "start_date": "2011-09-21", "completion_date": "2011-11-10", "has_results": false, "last_update_posted_date": "2025-10-07", "last_synced_at": "2026-09-12T02:23:17.525Z", "location_count": 1, "location_summary": "Las Vegas, Nevada", "locations": [ { "city": "Las Vegas", "state": "Nevada" } ], "official_url": "https://clinicaltrials.gov/study/NCT07211061" }, { "nct_id": "NCT01345292", "title": "A Study of the Relief of Tooth Sensitivity of an Experimental Mouthrinse Device", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dentin Sensitivity" ], "interventions": [ { "name": "Mouthwash", "type": "DEVICE" }, { "name": "Potassium nitrate toothpaste", "type": "DRUG" }, { "name": "Sodium fluoride toothpaste", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Johnson & Johnson Consumer and Personal Products Worldwide", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 226, "start_date": "2011-04", "completion_date": "2011-05", "has_results": true, "last_update_posted_date": "2015-06-10", "last_synced_at": "2026-09-12T02:23:17.525Z", "location_count": 1, "location_summary": "Las Vegas, Nevada", "locations": [ { "city": "Las Vegas", "state": "Nevada" } ], "official_url": "https://clinicaltrials.gov/study/NCT01345292" }, { "nct_id": "NCT04409873", "title": "Antiseptic Mouthwash / Pre-Procedural Rinse on SARS-CoV-2 Load (COVID-19)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "COVID-19", "SARS-CoV 2", "Severe Acute Respiratory Syndrome Coronavirus 2", "Virus Disease", "Coronavirus Infections", "Pharyngeal Diseases" ], "interventions": [ { "name": "Oral-B Mouth Sore mouthwash", "type": "DRUG" }, { "name": "Crest Pro-Health Multi-Protection mouthwash", "type": "DRUG" }, { "name": "CloSYS Ultra Sensitive Rinse mouthwash", "type": "DRUG" }, { "name": "Distilled water", "type": "DRUG" }, { "name": "Listerine Zero Mouthwash Product", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 54, "start_date": "2021-03-31", "completion_date": "2022-09-10", "has_results": true, "last_update_posted_date": "2023-11-18", "last_synced_at": "2026-09-12T02:23:17.525Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04409873" }, { "nct_id": "NCT04750005", "title": "A Twelve Week Study of Virtually Supervised Mouth Rinse and Flossing", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Listerine Cool Mint", "type": "OTHER" }, { "name": "Colgate Cavity Protection Toothpaste", "type": "OTHER" }, { "name": "Reach Unflavored Waxed Dental Floss", "type": "OTHER" }, { "name": "American Dental Association (ADA) Ref Toothbrush", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 209, "start_date": "2020-10-23", "completion_date": "2021-02-01", "has_results": false, "last_update_posted_date": "2022-02-16", "last_synced_at": "2026-09-12T02:23:17.525Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT04750005" }, { "nct_id": "NCT01156376", "title": "Oral Irritation Study of Two Experimental Mouthrinses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Oral Manifestations" ], "interventions": [ { "name": "Potassium Oxalate without Fluoride", "type": "DEVICE" }, { "name": "Potassium Oxalate with Fluoride", "type": "DEVICE" }, { "name": "Active Comparator PO-116-A", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Johnson & Johnson Consumer and Personal Products Worldwide", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 80, "start_date": "2010-06", "completion_date": "2010-07", "has_results": true, "last_update_posted_date": "2015-08-24", "last_synced_at": "2026-09-12T02:23:17.525Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01156376" }, { "nct_id": "NCT04748783", "title": "Antiviral Efficacy and Acceptability of Mouth Rinses for Inactivation of COVID-19", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "COVID19", "Coronavirus Infection", "SARS CoV-2 Infection" ], "interventions": [ { "name": "Water", "type": "OTHER" }, { "name": "Peroxyl", "type": "OTHER" }, { "name": "Periogard", "type": "DRUG" }, { "name": "Colgate Total Zero", "type": "OTHER" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "University of North Carolina, Chapel Hill", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 2, "start_date": "2021-03-26", "completion_date": "2021-04-07", "has_results": true, "last_update_posted_date": "2022-02-16", "last_synced_at": "2026-09-12T02:23:17.525Z", "location_count": 1, "location_summary": "Chapel Hill, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT04748783" }, { "nct_id": "NCT07160166", "title": "Determination of the Oral Irritation Potential of Two Alcohol-Free Rinses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Oral Health" ], "interventions": [ { "name": "Prototype 1", "type": "OTHER" }, { "name": "Prototype 2", "type": "OTHER" }, { "name": "Marketed Comparator", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Kenvue Brands LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 169, "start_date": "2025-07-11", "completion_date": "2025-07-30", "has_results": false, "last_update_posted_date": "2025-09-08", "last_synced_at": "2026-09-12T02:23:17.525Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT07160166" }, { "nct_id": "NCT04802408", "title": "SARS-Cov-2 (COVID-19) Nasal Pharyngeal and Oral Pharyngeal Wash (SNOW) Trial", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Covid19", "SARS-CoV Infection" ], "interventions": [ { "name": "Shampoo and saline", "type": "COMBINATION_PRODUCT" }, { "name": "Saline and Listerine", "type": "COMBINATION_PRODUCT" }, { "name": "Shampoo and Listerine", "type": "COMBINATION_PRODUCT" }, { "name": "Saline and Saline", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "Milton S. Hershey Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 171, "start_date": "2021-10-01", "completion_date": "2026-05-30", "has_results": false, "last_update_posted_date": "2025-10-28", "last_synced_at": "2026-09-12T02:23:17.525Z", "location_count": 2, "location_summary": "Hershey, Pennsylvania • State College, Pennsylvania", "locations": [ { "city": "Hershey", "state": "Pennsylvania" }, { "city": "State College", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT04802408" }, { "nct_id": "NCT02366689", "title": "Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Dental Plaque", "Gingivitis" ], "interventions": [ { "name": "Triclosan/fluoride toothpaste", "type": "DRUG" }, { "name": "stannous fluoride toothpaste", "type": "DRUG" }, { "name": "fluoride only toothpaste", "type": "DRUG" }, { "name": "Cetylpyridinium chloride mouthwash", "type": "DRUG" }, { "name": "Fluoride only mouthwash", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Colgate Palmolive", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 179, "start_date": "2014-06", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2016-03-30", "last_synced_at": "2026-09-12T02:23:17.525Z", "location_count": 1, "location_summary": "Cedar Knolls, New Jersey", "locations": [ { "city": "Cedar Knolls", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT02366689" } ] }