{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lithium+%2F+Fluoxetine", "query": { "intervention": "Lithium / Fluoxetine" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 7, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-21T08:54:27.418Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00612807", "title": "Treatment of Mood and Marriage Study (TOMMS)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Major Depressive Disorder", "Partner Relational Disorder (V61.10)" ], "interventions": [ { "name": "Weekly marital therapy", "type": "BEHAVIORAL" }, { "name": "As indicated: Sertraline, bupropion, venlafaxine, mirtazepine, nortriptyline, tranylcypromine, lithium augmentation, etc.", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 42, "start_date": "2006-07", "completion_date": "2010-06", "has_results": true, "last_update_posted_date": "2013-06-24", "last_synced_at": "2026-09-21T08:54:27.418Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00612807" }, { "nct_id": "NCT00961961", "title": "Prevention of Relapse & Recurrence of Bipolar Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Lithium / Fluoxetine", "type": "DRUG" }, { "name": "Lithium / Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 177, "start_date": "2009-07-01", "completion_date": "2016-09-01", "has_results": true, "last_update_posted_date": "2020-10-19", "last_synced_at": "2026-09-21T08:54:27.418Z", "location_count": 2, "location_summary": "Chicago, Illinois • Philadelphia, Pennsylvania", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00961961" }, { "nct_id": "NCT02893371", "title": "Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Lithium Carbonate", "type": "DRUG" }, { "name": "Lamotrigine", "type": "DRUG" }, { "name": "Valproic Acid", "type": "DRUG" }, { "name": "Oxcarbazepine", "type": "DRUG" }, { "name": "Carbamazepine", "type": "DRUG" }, { "name": "Ziprasidone", "type": "DRUG" }, { "name": "Risperidone", "type": "DRUG" }, { "name": "Quetiapine", "type": "DRUG" }, { "name": "Olanzapine", "type": "DRUG" }, { "name": "Aripiprazole", "type": "DRUG" }, { "name": "Fluoxetine / Olanzapine", "type": "DRUG" }, { "name": "Haloperidol", "type": "DRUG" }, { "name": "Perphenazine", "type": "DRUG" }, { "name": "Clozapine", "type": "DRUG" }, { "name": "Asenapine", "type": "DRUG" }, { "name": "Lurasidone", "type": "DRUG" }, { "name": "Paliperidone", "type": "DRUG" }, { "name": "Mirtazapine", "type": "DRUG" }, { "name": "Bupropion", "type": "DRUG" }, { "name": "Desvenlafaxine", "type": "DRUG" }, { "name": "Duloxetine", "type": "DRUG" }, { "name": "Venlafaxine", "type": "DRUG" }, { "name": "Citalopram", "type": "DRUG" }, { "name": "Escitalopram", "type": "DRUG" }, { "name": "Fluoxetine", "type": "DRUG" }, { "name": "Fluvoxamine", "type": "DRUG" }, { "name": "Paroxetine", "type": "DRUG" }, { "name": "Sertraline", "type": "DRUG" }, { "name": "Vilazodone", "type": "DRUG" }, { "name": "Doxepin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of New Mexico", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1037352, "start_date": "2016-09", "completion_date": "2019-06-30", "has_results": false, "last_update_posted_date": "2024-03-12", "last_synced_at": "2026-09-21T08:54:27.418Z", "location_count": 1, "location_summary": "Albuquerque, New Mexico", "locations": [ { "city": "Albuquerque", "state": "New Mexico" } ], "official_url": "https://clinicaltrials.gov/study/NCT02893371" }, { "nct_id": "NCT00044616", "title": "Relapse Prevention for Bipolar Type-II Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bipolar Disorder", "Depression" ], "interventions": [ { "name": "Fluoxetine", "type": "DRUG" }, { "name": "Lithium", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 180, "start_date": "2001-02", "completion_date": "2007-01", "has_results": false, "last_update_posted_date": "2015-10-06", "last_synced_at": "2026-09-21T08:54:27.418Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00044616" }, { "nct_id": "NCT00581009", "title": "The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Major Depressive Disorder", "Bipolar Disorder" ], "interventions": [ { "name": "chronobiological augmentation", "type": "OTHER" }, { "name": "sertraline, lithium", "type": "DRUG" }, { "name": "one night of sleep deprivation and two FDG PET scans", "type": "RADIATION" } ], "intervention_types": [ "OTHER", "DRUG", "RADIATION" ], "sponsor": "University of California, Irvine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 49, "start_date": "2001-05-30", "completion_date": "2011-12-09", "has_results": true, "last_update_posted_date": "2024-10-17", "last_synced_at": "2026-09-21T08:54:27.418Z", "location_count": 2, "location_summary": "Irvine, California • La Jolla, California", "locations": [ { "city": "Irvine", "state": "California" }, { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00581009" }, { "nct_id": "NCT00080158", "title": "Treatment of Adolescent Suicide Attempters (TASA)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Depression", "Suicide, Attempted" ], "interventions": [ { "name": "fluoxetine", "type": "DRUG" }, { "name": "sertraline", "type": "DRUG" }, { "name": "citalopram", "type": "DRUG" }, { "name": "escitalopram", "type": "DRUG" }, { "name": "bupropion", "type": "DRUG" }, { "name": "mirtazapine", "type": "DRUG" }, { "name": "venlafaxine", "type": "DRUG" }, { "name": "lithium", "type": "DRUG" }, { "name": "Cognitive Behavioral Therapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "New York State Psychiatric Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "12 Years to 18 Years" }, "enrollment_count": 120, "start_date": "2004-03", "completion_date": "2007-06", "has_results": false, "last_update_posted_date": "2020-06-22", "last_synced_at": "2026-09-21T08:54:27.418Z", "location_count": 6, "location_summary": "Baltimore, Maryland • New York, New York • Durham, North Carolina + 2 more", "locations": [ { "city": "Baltimore", "state": "Maryland" }, { "city": "New York", "state": "New York" }, { "city": "New York", "state": "New York" }, { "city": "Durham", "state": "North Carolina" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00080158" }, { "nct_id": "NCT00691080", "title": "Understanding Sleep Problems in Children With Autism Spectrum Disorder", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Sleep Problems" ], "interventions": [], "intervention_types": [], "sponsor": "Baylor College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "4 Years", "maximum_age": "9 Years", "sex": "ALL", "summary": "4 Years to 9 Years" }, "enrollment_count": 58, "start_date": "2007-09", "completion_date": "2011-11", "has_results": false, "last_update_posted_date": "2016-01-13", "last_synced_at": "2026-09-21T08:54:27.418Z", "location_count": 3, "location_summary": "New York, New York • Portland, Oregon • Houston, Texas", "locations": [ { "city": "New York", "state": "New York" }, { "city": "Portland", "state": "Oregon" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00691080" } ] }