{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lobeline",
    "query": {
      "intervention": "Lobeline"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 65,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lobeline&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T05:16:09.138Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02414477",
      "title": "Metabolism of Deuterated NNN in Smokeless Tobacco Users",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Tobacco Toxicant Exposure"
      ],
      "interventions": [
        {
          "name": "Deuterated NNN",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 13,
      "start_date": "2018-04-15",
      "completion_date": "2020-02-21",
      "has_results": false,
      "last_update_posted_date": "2025-01-30",
      "last_synced_at": "2026-09-03T05:16:09.138Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02414477"
    },
    {
      "nct_id": "NCT06927700",
      "title": "Effects of FDA Authorized Smokeless Tobacco Claims Among US Adults Who Smoke Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Product Beliefs and Use"
      ],
      "interventions": [
        {
          "name": "Modified Risk Claim Type - None",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Product Brand - General Snus",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Product Brand - Copenhagen",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Modified Risk Claim Type - Multiple Diseases",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Modified Risk Claim Type - Lung Cancer",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 1257,
      "start_date": "2025-04-24",
      "completion_date": "2025-05-04",
      "has_results": true,
      "last_update_posted_date": "2026-03-04",
      "last_synced_at": "2026-09-03T05:16:09.138Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06927700"
    },
    {
      "nct_id": "NCT05111041",
      "title": "Smokeless Tobacco Cessation Intervention for Firefighters",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smokeless Tobacco Cessation"
      ],
      "interventions": [
        {
          "name": "#EnufSnuff.TXT- First Responder",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enough Snuff Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2022-01-25",
      "completion_date": "2024-01-10",
      "has_results": true,
      "last_update_posted_date": "2024-12-13",
      "last_synced_at": "2026-09-03T05:16:09.138Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05111041"
    },
    {
      "nct_id": "NCT00664703",
      "title": "Effectiveness of Lobeline in Treating Symptoms of ADHD in Adult Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Attention Deficit Disorder With Hyperactivity"
      ],
      "interventions": [
        {
          "name": "Lobeline sulfate",
          "type": "DRUG"
        },
        {
          "name": "Methylphenidate HCl",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yaupon Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 13,
      "start_date": "2008-07",
      "completion_date": "2010-01",
      "has_results": false,
      "last_update_posted_date": "2013-06-20",
      "last_synced_at": "2026-09-03T05:16:09.138Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00664703"
    },
    {
      "nct_id": "NCT00820495",
      "title": "Effectiveness of a Web-Assisted Quitline for Smokeless Tobacco Users",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tobacco Use Disorder"
      ],
      "interventions": [
        {
          "name": "Web + Phone",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Web Only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Phone Only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Oregon Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1683,
      "start_date": "2009-05",
      "completion_date": "2012-05",
      "has_results": false,
      "last_update_posted_date": "2013-08-05",
      "last_synced_at": "2026-09-03T05:16:09.138Z",
      "location_count": 2,
      "location_summary": "San Diego, California • Eugene, Oregon",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Eugene",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00820495"
    },
    {
      "nct_id": "NCT06566703",
      "title": "Testing ANSOS for Efficacy in Multi-Tribal Urban Communities",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smokeless Tobacco Cessation"
      ],
      "interventions": [
        {
          "name": "All Nations Snuff Out Smokeless",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Healthy Living",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Lehigh University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 384,
      "start_date": "2023-08-18",
      "completion_date": "2028-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-25",
      "last_synced_at": "2026-09-03T05:16:09.138Z",
      "location_count": 1,
      "location_summary": "Bethlehem, Pennsylvania",
      "locations": [
        {
          "city": "Bethlehem",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06566703"
    },
    {
      "nct_id": "NCT01337830",
      "title": "Pilot Study to Evaluate the Safety and Efficacy of Ariva® Silver Wintergreen in Reducing Cigarette Craving in Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Tobacco Use Disorder",
        "Smoking"
      ],
      "interventions": [
        {
          "name": "Ariva® Silver Wintergreen",
          "type": "OTHER"
        },
        {
          "name": "Silver Wintergreen",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Star Scientific, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "23 Years",
        "maximum_age": "72 Years",
        "sex": "ALL",
        "summary": "23 Years to 72 Years"
      },
      "enrollment_count": 111,
      "start_date": "2010-10",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2014-10-24",
      "last_synced_at": "2026-09-03T05:16:09.138Z",
      "location_count": 1,
      "location_summary": "Martinsburg, West Virginia",
      "locations": [
        {
          "city": "Martinsburg",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01337830"
    },
    {
      "nct_id": "NCT04358705",
      "title": "C-FLASH (Cigarillo Flavor and Abuse Liability, Attention, and Substitution in youtH)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Behaviors"
      ],
      "interventions": [
        {
          "name": "Aim 1: Online survey",
          "type": "OTHER"
        },
        {
          "name": "Eye Tracking Activity",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Eye tracking survey",
          "type": "OTHER"
        },
        {
          "name": "Online Experimental Marketplace (ETM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Aim 3 survey",
          "type": "OTHER"
        },
        {
          "name": "Cognitive Interviews",
          "type": "OTHER"
        },
        {
          "name": "Supplemental Aim 1 Interviews",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Case Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "28 Years",
        "sex": "ALL",
        "summary": "16 Years to 28 Years"
      },
      "enrollment_count": 658,
      "start_date": "2020-05-29",
      "completion_date": "2023-02-10",
      "has_results": false,
      "last_update_posted_date": "2024-03-06",
      "last_synced_at": "2026-09-03T05:16:09.138Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04358705"
    },
    {
      "nct_id": "NCT01867242",
      "title": "Methods Project 4: Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoker"
      ],
      "interventions": [
        {
          "name": "Cigarettes",
          "type": "OTHER"
        },
        {
          "name": "Snus",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2013-07",
      "completion_date": "2018-05",
      "has_results": true,
      "last_update_posted_date": "2023-05-03",
      "last_synced_at": "2026-09-03T05:16:09.138Z",
      "location_count": 3,
      "location_summary": "Minneapolis, Minnesota • Buffalo, New York • Columbus, Ohio",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01867242"
    },
    {
      "nct_id": "NCT03993769",
      "title": "CSD190101: A Study to Assess Nicotine Pharmacokinetic Parameters After Use of Two Smokeless Tobacco Products",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "A19010-F",
          "type": "OTHER"
        },
        {
          "name": "B19010-F",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RAI Services Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 64,
      "start_date": "2019-07-09",
      "completion_date": "2019-08-31",
      "has_results": false,
      "last_update_posted_date": "2019-10-25",
      "last_synced_at": "2026-09-03T05:16:09.138Z",
      "location_count": 6,
      "location_summary": "Rogers, Arkansas • Lexington, Kentucky • Springfield, Missouri + 3 more",
      "locations": [
        {
          "city": "Rogers",
          "state": "Arkansas"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Springfield",
          "state": "Missouri"
        },
        {
          "city": "High Point",
          "state": "North Carolina"
        },
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03993769"
    }
  ]
}