{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Local+Anesthetic+Solution&page=2",
    "query": {
      "intervention": "Local Anesthetic Solution",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Local+Anesthetic+Solution&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-23T03:43:02.176Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01622296",
      "title": "Comparison of Pain of Conventional to Buffered Local Anesthesia During Injection in Pediatric Dental Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Sodium bicarbonate",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "9 Years to 12 Years"
      },
      "enrollment_count": 20,
      "start_date": "2012-04",
      "completion_date": "2013-07",
      "has_results": true,
      "last_update_posted_date": "2014-03-17",
      "last_synced_at": "2026-09-23T03:43:02.176Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01622296"
    },
    {
      "nct_id": "NCT04928794",
      "title": "Thermal-Imaging Comparison of Nerve Blocks for Bilateral Mastectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anesthesia, Conduction"
      ],
      "interventions": [
        {
          "name": "Erector Spinae Plane Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Paravertebral Block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of New Mexico",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 8,
      "start_date": "2021-05-19",
      "completion_date": "2021-08-23",
      "has_results": true,
      "last_update_posted_date": "2024-10-21",
      "last_synced_at": "2026-09-23T03:43:02.176Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04928794"
    },
    {
      "nct_id": "NCT00941993",
      "title": "Anesthetic Effect of Lidocaine/Epinephrine Solution Delivered Via Iontophoresis to External Auditory Apparatus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Otitis Media",
        "Chronic Otitis Media",
        "Recurrent Acute Otitis Media"
      ],
      "interventions": [
        {
          "name": "Iontophoresis System (Acclarent)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Integra LifeSciences Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Months and older"
      },
      "enrollment_count": 109,
      "start_date": "2008-04",
      "completion_date": "2011-01",
      "has_results": true,
      "last_update_posted_date": "2024-07-12",
      "last_synced_at": "2026-09-23T03:43:02.176Z",
      "location_count": 1,
      "location_summary": "Spartanburg, South Carolina",
      "locations": [
        {
          "city": "Spartanburg",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00941993"
    },
    {
      "nct_id": "NCT03059498",
      "title": "PECS Block: Plasma Bupivacaine Level",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Nerve Blocks"
      ],
      "interventions": [
        {
          "name": "Unilateral PECS I and II block",
          "type": "PROCEDURE"
        },
        {
          "name": "Bilateral PECS I and II block",
          "type": "PROCEDURE"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2017-06-06",
      "completion_date": "2017-11-15",
      "has_results": false,
      "last_update_posted_date": "2021-10-15",
      "last_synced_at": "2026-09-23T03:43:02.176Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03059498"
    },
    {
      "nct_id": "NCT01053273",
      "title": "A Randomized, Equivalence Trial of Percutaneous Lumbar Adhesiolysis and Caudal Epidural Steroid Injections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Caudal Epidural Injection",
          "type": "PROCEDURE"
        },
        {
          "name": "percutaneous adhesiolysis",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Pain Management Center of Paducah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2010-02",
      "completion_date": "2014-01-27",
      "has_results": false,
      "last_update_posted_date": "2017-04-25",
      "last_synced_at": "2026-09-23T03:43:02.176Z",
      "location_count": 1,
      "location_summary": "Paducah, Kentucky",
      "locations": [
        {
          "city": "Paducah",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01053273"
    },
    {
      "nct_id": "NCT04865848",
      "title": "Comparison of Articaine Mandibular Infiltration to Lidocaine Inferior Alveolar Nerve Block in Pediatric Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "Dental local anesthesia",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "4 Years to 10 Years"
      },
      "enrollment_count": 42,
      "start_date": "2019-06-05",
      "completion_date": "2022-05-05",
      "has_results": false,
      "last_update_posted_date": "2024-05-09",
      "last_synced_at": "2026-09-23T03:43:02.176Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04865848"
    },
    {
      "nct_id": "NCT05767749",
      "title": "Split Face Study of the Duration of Local Anesthetics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anesthetics, Local"
      ],
      "interventions": [
        {
          "name": "lidocaine + epinephrine 1:100,000",
          "type": "DRUG"
        },
        {
          "name": "Ropivacaine 0.5% Injectable Solution",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine 0.5% Injectable Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 75,
      "start_date": "2023-03-14",
      "completion_date": "2023-07-31",
      "has_results": true,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-09-23T03:43:02.176Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05767749"
    },
    {
      "nct_id": "NCT01746940",
      "title": "Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diagnostic",
        "Procedures and Surgeries on or Through Accessible Mucous Membranes",
        "of the Nasal Cavities"
      ],
      "interventions": [
        {
          "name": "Cocaine HCl 4% Topical Solution",
          "type": "DRUG"
        },
        {
          "name": "Cocaine HCl 10% Topical Solution",
          "type": "DRUG"
        },
        {
          "name": "Placebo Topical Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Lannett Company, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 159,
      "start_date": "2014-03",
      "completion_date": "2015-07",
      "has_results": true,
      "last_update_posted_date": "2017-05-12",
      "last_synced_at": "2026-09-23T03:43:02.176Z",
      "location_count": 2,
      "location_summary": "Bridgeport, Connecticut • Plano, Texas",
      "locations": [
        {
          "city": "Bridgeport",
          "state": "Connecticut"
        },
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01746940"
    },
    {
      "nct_id": "NCT05003765",
      "title": "Are Superficial Parasternal Intercostal Plane (SPIP) Blocks With Bupivacaine and With or Without Adjuvants Helpful for Post-operative Pain After Coronary Artery Bypass Grafting?",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-operative Pain Management"
      ],
      "interventions": [
        {
          "name": "Bupivacaine 0.25% Injectable Solution",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine 0.25% Injectable Solution, Magnesium Sulfate 200 mg",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine 0.25% Injectable Solution, Magnesium Sulfate 200 mg, Buprenorphine 300 mcg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wayne State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 200,
      "start_date": "2020-08-06",
      "completion_date": "2022-05-01",
      "has_results": false,
      "last_update_posted_date": "2021-08-12",
      "last_synced_at": "2026-09-23T03:43:02.176Z",
      "location_count": 1,
      "location_summary": "Pontiac, Michigan",
      "locations": [
        {
          "city": "Pontiac",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05003765"
    },
    {
      "nct_id": "NCT05846399",
      "title": "CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cat Bite",
        "Hand Injuries",
        "Arm Injury",
        "Infection, Bacterial",
        "Anti-bacterial Agents"
      ],
      "interventions": [
        {
          "name": "Amoxicillin/clavulanate",
          "type": "DRUG"
        },
        {
          "name": "Ciprofloxacin",
          "type": "DRUG"
        },
        {
          "name": "Clindamycin",
          "type": "DRUG"
        },
        {
          "name": "Placebo (microcrystalline cellulose)",
          "type": "OTHER"
        },
        {
          "name": "Wound management",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 72,
      "start_date": "2023-09-07",
      "completion_date": "2027-08-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-15",
      "last_synced_at": "2026-09-23T03:43:02.176Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05846399"
    }
  ]
}