{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Local+block&page=20",
    "query": {
      "intervention": "Local block",
      "page": 20
    },
    "page_size": 10
  },
  "pagination": {
    "page": 20,
    "page_size": 10,
    "total_count": 597,
    "total_pages": 60,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Local+block&page=21&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Local+block&page=19&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-01T18:21:33.203Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00720330",
      "title": "Lidocaine and Ketamine Versus Standard Care on Acute and Chronic Pain",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain",
        "Nausea"
      ],
      "interventions": [
        {
          "name": "ropivacaine",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine/Ketamine",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "MALE",
        "summary": "18 Years to 75 Years · Male only"
      },
      "enrollment_count": 12,
      "start_date": "2008-07",
      "completion_date": "2010-02",
      "has_results": true,
      "last_update_posted_date": "2019-03-12",
      "last_synced_at": "2026-11-01T18:21:33.203Z",
      "location_count": 1,
      "location_summary": "Mayfield Heights, Ohio",
      "locations": [
        {
          "city": "Mayfield Heights",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00720330"
    },
    {
      "nct_id": "NCT00667264",
      "title": "Ambulatory Continuous Peripheral Nerve Blocks for Treatment of Post-Amputation Phantom Limb and Stump Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Phantom Limb",
        "Stump Pain"
      ],
      "interventions": [
        {
          "name": "perineural ropivacaine",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2008-10",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2012-06-28",
      "last_synced_at": "2026-11-01T18:21:33.203Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00667264"
    },
    {
      "nct_id": "NCT04333095",
      "title": "Sternal Block With Liposomal Bupivacaine vs. Saline Prior to Incision in Cardiac Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cardiovascular Surgery",
        "Pain, Postoperative",
        "Block"
      ],
      "interventions": [
        {
          "name": "Liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline Flush, 0.9% Injectable Solution_#1",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Baylor Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2020-02-06",
      "completion_date": "2021-06-26",
      "has_results": true,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-11-01T18:21:33.203Z",
      "location_count": 1,
      "location_summary": "Plano, Texas",
      "locations": [
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04333095"
    },
    {
      "nct_id": "NCT07064200",
      "title": "TAP Block Timing Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bariatric or General Abdominal Surgeries",
        "Bariatric Surgery Patients"
      ],
      "interventions": [
        {
          "name": "TAP Block",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 150,
      "start_date": "2025-07-14",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-11-01T18:21:33.203Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07064200"
    },
    {
      "nct_id": "NCT06731998",
      "title": "Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Oncologic Surgery",
        "Cancer",
        "Cancer Surgery",
        "Hepatic Cancer",
        "Gastric (Cardia, Body) Cancer",
        "Biliary Tract Cancer",
        "Pancreatic Cancer Resectable",
        "Gynecologic Cancers",
        "Gastrointestinal Cancers",
        "Colorectal Cancer",
        "Minimally Invasive Surgical Procedures"
      ],
      "interventions": [
        {
          "name": "Local Anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Laparoscopic Transversus Abdominis Plane block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 48,
      "start_date": "2025-02-05",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-09-18",
      "last_synced_at": "2026-11-01T18:21:33.203Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06731998"
    },
    {
      "nct_id": "NCT03731221",
      "title": "Pectoral Fascial Plane and Serratus Anterior Plane Blocks With Bupivacaine v. Liposomal Bupivacaine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Video Assisted Thoracic Surgery"
      ],
      "interventions": [
        {
          "name": "Bupi HCI and lipo bupi",
          "type": "DRUG"
        },
        {
          "name": "Bupi HCI",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 196,
      "start_date": "2018-11-01",
      "completion_date": "2024-09-19",
      "has_results": false,
      "last_update_posted_date": "2025-06-10",
      "last_synced_at": "2026-11-01T18:21:33.203Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03731221"
    },
    {
      "nct_id": "NCT05763667",
      "title": "Pilot: Intraoperative TAP Block and Post-operative Pain Control for Minimally Invasive Hysterectomy for Endometrial Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Post Operative Pain",
        "Gynecologic Cancer"
      ],
      "interventions": [
        {
          "name": "Liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacain",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 80 Years · Female only"
      },
      "enrollment_count": 15,
      "start_date": "2024-01-01",
      "completion_date": "2024-09-09",
      "has_results": false,
      "last_update_posted_date": "2025-04-24",
      "last_synced_at": "2026-11-01T18:21:33.203Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05763667"
    },
    {
      "nct_id": "NCT01333943",
      "title": "Saphenous Nerve Block Versus Femoral Nerve Block for Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Study Group: Experimental",
          "type": "PROCEDURE"
        },
        {
          "name": "Control Group",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 94,
      "start_date": "2011-03",
      "completion_date": "2011-11",
      "has_results": true,
      "last_update_posted_date": "2022-05-11",
      "last_synced_at": "2026-11-01T18:21:33.203Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01333943"
    },
    {
      "nct_id": "NCT07254650",
      "title": "Combination Versus Alone Liposomal Bupivacaine Blocks in Minimally Invasive Thoracic Surgery-1",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lung Cancer (Diagnosis)"
      ],
      "interventions": [
        {
          "name": "Arm 1 \"LipoB-I\": Liposomal Bupivacaine via Multi-Level Intercostal Nerve Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Arm 2 \"LipoB-S\": Liposomal Bupivacaine via Serratus Anterior Plane Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Arm 3 \"LipoB-C\": Liposomal Bupivacaine Administered via Combination Block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2026-10",
      "completion_date": "2028-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-26",
      "last_synced_at": "2026-11-01T18:21:33.203Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07254650"
    },
    {
      "nct_id": "NCT04226131",
      "title": "MusculRA: The Effects of Rheumatoid Arthritis on Skeletal Muscle Biomechanics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rheumatoid Arthritis",
        "Healthy Controls"
      ],
      "interventions": [
        {
          "name": "Blood Draw",
          "type": "OTHER"
        },
        {
          "name": "Disease Activity (DAS-28) Assessment",
          "type": "OTHER"
        },
        {
          "name": "Skeletal Muscle Mitochondrial Respiratory Capacity",
          "type": "OTHER"
        },
        {
          "name": "Muscle Biopsy",
          "type": "OTHER"
        },
        {
          "name": "Body Composition",
          "type": "OTHER"
        },
        {
          "name": "Cardiopulmonary Exercise Test (CPET)",
          "type": "OTHER"
        },
        {
          "name": "Strength Testing",
          "type": "OTHER"
        },
        {
          "name": "Questionnaires",
          "type": "OTHER"
        },
        {
          "name": "Skeletal Muscle Biomechanical Property Assessment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "25 Years to 75 Years"
      },
      "enrollment_count": 21,
      "start_date": "2020-09-09",
      "completion_date": "2023-07-07",
      "has_results": false,
      "last_update_posted_date": "2023-07-13",
      "last_synced_at": "2026-11-01T18:21:33.203Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04226131"
    }
  ]
}