{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Local+block&page=9",
    "query": {
      "intervention": "Local block",
      "page": 9
    },
    "page_size": 10
  },
  "pagination": {
    "page": 9,
    "page_size": 10,
    "total_count": 597,
    "total_pages": 60,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Local+block&page=10&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Local+block&page=8&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-01T03:08:35.422Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05579509",
      "title": "Personalizing Preprocedural Sedation for Regional Anesthesia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Catastrophizing Pain"
      ],
      "interventions": [
        {
          "name": "Midazolam and Fentanyl",
          "type": "DRUG"
        },
        {
          "name": "Educational Reassurance",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 82,
      "start_date": "2022-10-22",
      "completion_date": "2024-05-24",
      "has_results": false,
      "last_update_posted_date": "2025-03-26",
      "last_synced_at": "2026-11-01T03:08:35.422Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05579509"
    },
    {
      "nct_id": "NCT02276495",
      "title": "Can Single-Injection Adductor Canal Blocks Improve PostOp Pain Relief in Patients Undergoing Total Knee Arthroplasty?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain Management"
      ],
      "interventions": [
        {
          "name": "ACB Control - 20 ml saline injection for ACB",
          "type": "OTHER"
        },
        {
          "name": "ACB Study - 20 ml 0.5% Ropivacaine for Adductor Canal Block",
          "type": "DRUG"
        },
        {
          "name": "Local infiltration - 100 mLs of a solution containing: Ropivacaine + Epinephrine + Ketorolac + Clonidine + 0.9% Normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 55,
      "start_date": "2015-01-01",
      "completion_date": "2024-09-30",
      "has_results": true,
      "last_update_posted_date": "2024-10-29",
      "last_synced_at": "2026-11-01T03:08:35.422Z",
      "location_count": 1,
      "location_summary": "Orange, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02276495"
    },
    {
      "nct_id": "NCT03854344",
      "title": "Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain, Postoperative",
        "Burns"
      ],
      "interventions": [
        {
          "name": "Lidocaine Hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Liposomal bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine Hydrochloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2019-03-18",
      "completion_date": "2025-10-27",
      "has_results": true,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-11-01T03:08:35.422Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03854344"
    },
    {
      "nct_id": "NCT03261193",
      "title": "ITM + Bupivacaine QLB vs. ITM + Sham Saline QLB for Cesarean Delivery Pain",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "ITM + Sham QLB",
          "type": "DRUG"
        },
        {
          "name": "ITM + Bupivacaine QLB",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Nicholas Schott",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 21,
      "start_date": "2017-09-05",
      "completion_date": "2022-11-11",
      "has_results": true,
      "last_update_posted_date": "2024-05-06",
      "last_synced_at": "2026-11-01T03:08:35.422Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03261193"
    },
    {
      "nct_id": "NCT00418483",
      "title": "A Dose Escalation and Safety Study of Plasmin (Human) In Acute Lower Extremity Native Artery or Bypass Graft Occlusion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Arterial Occlusive Diseases"
      ],
      "interventions": [
        {
          "name": "Plasmin (Human) 25 mg",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Plasmin (Human) 50 mg",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Plasmin (Human) 75 mg",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Plasmin (Human) 100 mg",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Plasmin (Human) 125 mg",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Plasmin (Human) 150 mg",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Plasmin (Human) 175 mg",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Grifols Therapeutics LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 83,
      "start_date": "2007-03",
      "completion_date": "2010-04",
      "has_results": false,
      "last_update_posted_date": "2016-10-31",
      "last_synced_at": "2026-11-01T03:08:35.422Z",
      "location_count": 1,
      "location_summary": "Toledo, Ohio",
      "locations": [
        {
          "city": "Toledo",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00418483"
    },
    {
      "nct_id": "NCT02427724",
      "title": "The Effect of Topical Anesthetics on Patients' Pain and Operative Experience During Treatment With QSwitched Laser",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Lentigo"
      ],
      "interventions": [
        {
          "name": "lidocaine 2.5%/prilocaine 2.5% topical anesthetic",
          "type": "DRUG"
        },
        {
          "name": "lidocaine 7%/tetracaine 7% topical anesthetic",
          "type": "DRUG"
        },
        {
          "name": "placebo vehicle",
          "type": "DRUG"
        },
        {
          "name": "Q-switched 532nm Laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "25 Years to 65 Years · Female only"
      },
      "enrollment_count": 48,
      "start_date": "2015-04",
      "completion_date": "2024-05-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-11-01T03:08:35.422Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02427724"
    },
    {
      "nct_id": "NCT01629537",
      "title": "A Randomized, Placebo-Controlled Trial of Stellate Ganglion Block in the Treatment of Post Traumatic Stress Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Post Traumatic Stress Disorder (PTSD)"
      ],
      "interventions": [
        {
          "name": "Stellate Ganglion Block injection with ropivicane",
          "type": "PROCEDURE"
        },
        {
          "name": "Placebo Procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "United States Naval Medical Center, San Diego",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2011-06",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2017-03-30",
      "last_synced_at": "2026-11-01T03:08:35.422Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01629537"
    },
    {
      "nct_id": "NCT04513145",
      "title": "Adductor Canal Block",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Osteoarthritis",
        "Total Knee Replacement"
      ],
      "interventions": [
        {
          "name": "Ropivacaine injection",
          "type": "DRUG"
        },
        {
          "name": "Saline Injection",
          "type": "DRUG"
        },
        {
          "name": "Total Knee Arthroplasty",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "OrthoCarolina Research Institute, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "30 Years to 85 Years"
      },
      "enrollment_count": 93,
      "start_date": "2020-10-09",
      "completion_date": "2025-05-23",
      "has_results": false,
      "last_update_posted_date": "2026-04-06",
      "last_synced_at": "2026-11-01T03:08:35.422Z",
      "location_count": 1,
      "location_summary": "Charlotte, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04513145"
    },
    {
      "nct_id": "NCT04669145",
      "title": "Regional Anesthesia in Pediatric Orthopaedic Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Anesthesia, Local",
        "Anesthesia",
        "Orthopedic Disorder"
      ],
      "interventions": [
        {
          "name": "Ropivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ochsner Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "5 Years to 18 Years"
      },
      "enrollment_count": 24,
      "start_date": "2021-06-24",
      "completion_date": "2024-04-22",
      "has_results": false,
      "last_update_posted_date": "2025-07-29",
      "last_synced_at": "2026-11-01T03:08:35.422Z",
      "location_count": 1,
      "location_summary": "Jefferson, Louisiana",
      "locations": [
        {
          "city": "Jefferson",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04669145"
    },
    {
      "nct_id": "NCT02970097",
      "title": "Single Shot Infraclavicular Brachial Plexus Block vs Local Infiltration After Wrist Arthroscopy Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrist Injuries",
        "Postoperative Pain Control"
      ],
      "interventions": [
        {
          "name": "20ml bolus of 0.5% ropivicaine",
          "type": "DRUG"
        },
        {
          "name": "10 ml of 0.5% ropivicaine",
          "type": "DRUG"
        },
        {
          "name": "Midazolam",
          "type": "DRUG"
        },
        {
          "name": "Fentanyl",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2016-09",
      "completion_date": "2018-10-05",
      "has_results": false,
      "last_update_posted_date": "2020-02-21",
      "last_synced_at": "2026-11-01T03:08:35.422Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02970097"
    }
  ]
}