{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Local+injection+of+normal+saline&page=2",
    "query": {
      "intervention": "Local injection of normal saline",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Local+injection+of+normal+saline&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-27T13:36:04.367Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05294640",
      "title": "Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Eyelid Tumor",
        "Eyelid Bump",
        "Eyelid Deformity",
        "Eyelid Abscess",
        "Eyelid Boil",
        "Eyelid Papilloma",
        "Anesthesia, Local",
        "Ophthalmology"
      ],
      "interventions": [
        {
          "name": "0.9% Bacteriostatic Local Anesthetic Injection",
          "type": "DRUG"
        },
        {
          "name": "1% Lidocaine with 1:100,000 epinephrine Local Anesthetic Injection",
          "type": "DRUG"
        },
        {
          "name": "Eyelid Lesion Removal",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "18 Years to 110 Years"
      },
      "enrollment_count": 95,
      "start_date": "2022-05-17",
      "completion_date": "2023-02-21",
      "has_results": true,
      "last_update_posted_date": "2025-07-08",
      "last_synced_at": "2026-09-27T13:36:04.367Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05294640"
    },
    {
      "nct_id": "NCT07145801",
      "title": "Y-90 Treatment Response Using Transarterial Radioembolization",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "HCC",
        "Hepatocellular Carcinoma",
        "Liver Cancer",
        "Hepatic Neoplasm",
        "Primary Liver Cancer",
        "Liver Neoplasm"
      ],
      "interventions": [
        {
          "name": "Lumason",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sonazoid",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2025-09-11",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-10",
      "last_synced_at": "2026-09-27T13:36:04.367Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07145801"
    },
    {
      "nct_id": "NCT02517905",
      "title": "Evaluation of EXPAREL for Prolonged Postsurgical Analgesia in Subjects Undergoing Third Molar Extraction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dental Pain"
      ],
      "interventions": [
        {
          "name": "Bupivacaine liposome",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pacira Pharmaceuticals, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 166,
      "start_date": "2015-08",
      "completion_date": "2016-01",
      "has_results": true,
      "last_update_posted_date": "2020-12-10",
      "last_synced_at": "2026-09-27T13:36:04.367Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02517905"
    },
    {
      "nct_id": "NCT06450392",
      "title": "The Effect of Local and Systemic Tranexamic Acid on Edema and Ecchymosis in Orbital Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Orbital Edema",
        "Orbital Ecchymosis"
      ],
      "interventions": [
        {
          "name": "Tranexamic acid injection",
          "type": "DRUG"
        },
        {
          "name": "Tranexamic Acid in NaCl,Iso-Os 1,000 Mg/100 mL (10 Mg/mL) INTRAVEN INTRAVENOUS SOLUTION, PIGGYBACK (ML)",
          "type": "DRUG"
        },
        {
          "name": "normal saline - injection",
          "type": "DRUG"
        },
        {
          "name": "normal saline - intravenous",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2024-10-07",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-16",
      "last_synced_at": "2026-09-27T13:36:04.367Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06450392"
    },
    {
      "nct_id": "NCT03305575",
      "title": "Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cervical Incompetence"
      ],
      "interventions": [
        {
          "name": "Chloroprocaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2017-10-13",
      "completion_date": "2018-08-24",
      "has_results": true,
      "last_update_posted_date": "2020-08-25",
      "last_synced_at": "2026-09-27T13:36:04.367Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03305575"
    },
    {
      "nct_id": "NCT06213454",
      "title": "Transversus Abdominis Plane Block Compared to Local Anesthetic Wound Infiltration in Gynecologic Oncology Surgery",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Analgesia",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "TAP Anesthesia",
          "type": "DRUG"
        },
        {
          "name": "Surgeon-Initiated Local Anesthetic",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 82,
      "start_date": "2024-03-26",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2026-08-20",
      "last_synced_at": "2026-09-27T13:36:04.367Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06213454"
    },
    {
      "nct_id": "NCT03840122",
      "title": "ACB + IPACK Block With or Without Local Infiltration in RA-TKA",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Arthropathy"
      ],
      "interventions": [
        {
          "name": "ACB + IPACK block with injection of local anesthetic",
          "type": "OTHER"
        },
        {
          "name": "ACB + IPACK block without injection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Louisville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2019-10-08",
      "completion_date": "2019-10-08",
      "has_results": false,
      "last_update_posted_date": "2019-10-10",
      "last_synced_at": "2026-09-27T13:36:04.367Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03840122"
    },
    {
      "nct_id": "NCT02851888",
      "title": "Use of Regional Anesthesia in Hip Arthroscopy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hip Injuries"
      ],
      "interventions": [
        {
          "name": "Ropivacaine",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline Sham Injection",
          "type": "OTHER"
        },
        {
          "name": "General Anesthesia",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Georgetown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 70,
      "start_date": "2016-07",
      "completion_date": "2018-08",
      "has_results": false,
      "last_update_posted_date": "2018-02-19",
      "last_synced_at": "2026-09-27T13:36:04.367Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02851888"
    },
    {
      "nct_id": "NCT01759459",
      "title": "Local Anesthetics for Pain Reduction Prior to IV Line Placement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain",
        "Local Anesthesia for Peripheral Intravenous Catheterization"
      ],
      "interventions": [
        {
          "name": "Lidocaine",
          "type": "DRUG"
        },
        {
          "name": "Buffered Lidocaine",
          "type": "DRUG"
        },
        {
          "name": "Bacteriostatic Normal Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Allina Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2013-01",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2022-07-15",
      "last_synced_at": "2026-09-27T13:36:04.367Z",
      "location_count": 1,
      "location_summary": "Saint Paul, Minnesota",
      "locations": [
        {
          "city": "Saint Paul",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01759459"
    },
    {
      "nct_id": "NCT01286870",
      "title": "Becker Continued Access Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Breast Reconstruction"
      ],
      "interventions": [
        {
          "name": "Mentor Becker 25 Expander/Breast Implant",
          "type": "DEVICE"
        },
        {
          "name": "Mentor Becker 50 Expander/Breast Implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mentor Worldwide, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 11,
      "start_date": "2009-06-01",
      "completion_date": "2014-03-04",
      "has_results": true,
      "last_update_posted_date": "2019-03-06",
      "last_synced_at": "2026-09-27T13:36:04.367Z",
      "location_count": 1,
      "location_summary": "Santa Barbara, California",
      "locations": [
        {
          "city": "Santa Barbara",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01286870"
    }
  ]
}