{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Low+Fat%2FHigh+Carbohydrate&page=2",
    "query": {
      "intervention": "Low Fat/High Carbohydrate",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 142,
    "total_pages": 15,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Low+Fat%2FHigh+Carbohydrate&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Low+Fat%2FHigh+Carbohydrate&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-01T12:36:09.488Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03946774",
      "title": "Dietary Protein and Monocyte/Macrophage Mammalian Target of Rapamycin (mTOR) Signaling",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dietary Protein"
      ],
      "interventions": [
        {
          "name": "Dietary protein shake",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2019-10-01",
      "completion_date": "2023-05-04",
      "has_results": false,
      "last_update_posted_date": "2024-10-26",
      "last_synced_at": "2026-10-01T12:36:09.488Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03946774"
    },
    {
      "nct_id": "NCT03785808",
      "title": "Reducing Insulin, Growth Hormones, and Tumors",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diet Modification",
        "Lung Cancer"
      ],
      "interventions": [
        {
          "name": "Special Diet Therapy (low-carb)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Special Diet Therapy (low-fat)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Special Diet Therapy (USDA control)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Fred Hutchinson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2018-12-21",
      "completion_date": "2019-08-05",
      "has_results": false,
      "last_update_posted_date": "2019-08-12",
      "last_synced_at": "2026-10-01T12:36:09.488Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03785808"
    },
    {
      "nct_id": "NCT06748950",
      "title": "Ketogenic Metabolic Therapy in Schizophrenia, Bipolar Disorder, Major Depressive Disorder: Deep Omic Profiling",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Schizophrenia",
        "Schizophrenia and Related Disorders",
        "Bipolar Disorder",
        "Bipolar and Related Disorders",
        "Major Depressive Disorder",
        "Major Depression Severe",
        "Ketogenic Dieting",
        "Ketosis",
        "Metabolic Disease",
        "Metabolic Syndrome"
      ],
      "interventions": [
        {
          "name": "LCHF Ketogenic Diet",
          "type": "OTHER"
        },
        {
          "name": "Diet-as-Usual (DAU)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 120,
      "start_date": "2025-07",
      "completion_date": "2028-07",
      "has_results": false,
      "last_update_posted_date": "2025-05-16",
      "last_synced_at": "2026-10-01T12:36:09.488Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06748950"
    },
    {
      "nct_id": "NCT01936935",
      "title": "Clinical Trial to Assess the Effects of Dairy on Insulin Sensitivity and β-Cell Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "Low-fat dairy",
          "type": "OTHER"
        },
        {
          "name": "Sugar-sweetened beverages",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Provident Clinical Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "18 Years to 74 Years"
      },
      "enrollment_count": 44,
      "start_date": "2012-09",
      "completion_date": "2013-09",
      "has_results": false,
      "last_update_posted_date": "2023-12-04",
      "last_synced_at": "2026-10-01T12:36:09.488Z",
      "location_count": 1,
      "location_summary": "Addison, Illinois",
      "locations": [
        {
          "city": "Addison",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01936935"
    },
    {
      "nct_id": "NCT03935854",
      "title": "Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Ketogenic Dieting",
        "Metabolic Syndrome",
        "Bipolar Disorder",
        "Schizophrenia",
        "Weight Gain",
        "Psychotropic Agents Causing Adverse Effects in Therapeutic Use",
        "Brain Metabolic Disorder"
      ],
      "interventions": [
        {
          "name": "LCHF, Ketogenic Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 23,
      "start_date": "2019-02-13",
      "completion_date": "2022-08-11",
      "has_results": false,
      "last_update_posted_date": "2024-12-17",
      "last_synced_at": "2026-10-01T12:36:09.488Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03935854"
    },
    {
      "nct_id": "NCT00299273",
      "title": "High Fat - High Protein Diet in the Treatment of Obesity",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Low calorie high fat/protein diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rockefeller University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "25 Years to 50 Years · Female only"
      },
      "enrollment_count": 8,
      "start_date": "2006-03",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2015-06-08",
      "last_synced_at": "2026-10-01T12:36:09.488Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00299273"
    },
    {
      "nct_id": "NCT03207841",
      "title": "Low Carbohydrate/High Protein Diet to Improve Metabolic Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord",
        "Metabolic Syndrome",
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "LC/HP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 60,
      "start_date": "2017-11-01",
      "completion_date": "2022-08-29",
      "has_results": false,
      "last_update_posted_date": "2023-03-27",
      "last_synced_at": "2026-10-01T12:36:09.488Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03207841"
    },
    {
      "nct_id": "NCT03729479",
      "title": "The MHERO Study (Michigan's Hypertension, Diabetes, and Obesity Education Research Online)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Type2 Diabetes Mellitus",
        "Hypertension",
        "PreDiabetes",
        "Overweight and Obesity"
      ],
      "interventions": [
        {
          "name": "DASH diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Very low carbohydrate, ketogenic diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Extras",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 94,
      "start_date": "2018-11-01",
      "completion_date": "2020-08-09",
      "has_results": false,
      "last_update_posted_date": "2020-09-29",
      "last_synced_at": "2026-10-01T12:36:09.488Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03729479"
    },
    {
      "nct_id": "NCT02984540",
      "title": "Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Insulin Resistance"
      ],
      "interventions": [
        {
          "name": "Low-Carbohydrate Diet",
          "type": "OTHER"
        },
        {
          "name": "Low-Fat Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 25,
      "start_date": "2015-02",
      "completion_date": "2017-04-03",
      "has_results": false,
      "last_update_posted_date": "2025-07-28",
      "last_synced_at": "2026-10-01T12:36:09.488Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02984540"
    },
    {
      "nct_id": "NCT03548948",
      "title": "Obesity, Iron Regulation and Colorectal Cancer Risk",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colon Inflammation",
        "Iron Malabsorption",
        "Obesity",
        "Diet Modification"
      ],
      "interventions": [
        {
          "name": "High heme iron diet",
          "type": "OTHER"
        },
        {
          "name": "Low iron diet",
          "type": "OTHER"
        },
        {
          "name": "Plant-based high non-heme iron diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "55 Years to 70 Years · Female only"
      },
      "enrollment_count": 17,
      "start_date": "2015-07-15",
      "completion_date": "2019-06-30",
      "has_results": false,
      "last_update_posted_date": "2019-09-27",
      "last_synced_at": "2026-10-01T12:36:09.488Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03548948"
    }
  ]
}