{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Low+Flow+Oxygen",
    "query": {
      "intervention": "Low Flow Oxygen"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 25,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Low+Flow+Oxygen&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T12:24:06.675Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05967507",
      "title": "Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Airway Management"
      ],
      "interventions": [
        {
          "name": "Low-flow nasal supplemental oxygen with a conventional nasal cannula during tracheal intubation with the C-MAC video laryngoscope",
          "type": "DEVICE"
        },
        {
          "name": "High-flow nasal supplemental oxygen (Fisher & Paykel, Auckland, New Zealand) during tracheal intubation with the C-MAC video laryngoscope",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Thomas Riva",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "52 Weeks",
        "sex": "ALL",
        "summary": "Up to 52 Weeks"
      },
      "enrollment_count": 1192,
      "start_date": "2023-12-01",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-09-06T12:24:06.675Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05967507"
    },
    {
      "nct_id": "NCT02460653",
      "title": "Effects of High Flow Nasal Cannula on Deadspace Reduction and Regional Distribution of Ventilation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Insufficiency",
        "Hypoxia"
      ],
      "interventions": [
        {
          "name": "HFNC Flow Rate",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Weeks",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "4 Weeks to 17 Years"
      },
      "enrollment_count": 40,
      "start_date": "2015-05-01",
      "completion_date": "2021-07-01",
      "has_results": false,
      "last_update_posted_date": "2019-06-04",
      "last_synced_at": "2026-09-06T12:24:06.675Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Seattle, Washington",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02460653"
    },
    {
      "nct_id": "NCT06336642",
      "title": "Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Dyspnea"
      ],
      "interventions": [
        {
          "name": "SPOT-ON Early Start",
          "type": "BEHAVIORAL"
        },
        {
          "name": "SPOT-ON Delayed Start",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2024-06-11",
      "completion_date": "2032-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-04",
      "last_synced_at": "2026-09-06T12:24:06.675Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06336642"
    },
    {
      "nct_id": "NCT04217746",
      "title": "Effects of High Flow Nasal Cannula on Sputum Clearance in Acute Exacerbation of Chronic Obstructive Pulmonary Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease",
        "COPD Exacerbation",
        "Airflow Obstruction"
      ],
      "interventions": [
        {
          "name": "High Flow Nasal Cannula",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2020-02-01",
      "completion_date": "2025-02-01",
      "has_results": false,
      "last_update_posted_date": "2025-07-22",
      "last_synced_at": "2026-09-06T12:24:06.675Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04217746"
    },
    {
      "nct_id": "NCT02587832",
      "title": "High Flow Nasal Cannula in Comparison With Nasal Continuous Positive Airway Pressure in the Management of Respiratory Distress Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "HHHFNC",
          "type": "DEVICE"
        },
        {
          "name": "NCPAP",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sidra Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 60,
      "start_date": "2009-07",
      "completion_date": "2012-04",
      "has_results": false,
      "last_update_posted_date": "2015-10-27",
      "last_synced_at": "2026-09-06T12:24:06.675Z",
      "location_count": 1,
      "location_summary": "Akron, Ohio",
      "locations": [
        {
          "city": "Akron",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02587832"
    },
    {
      "nct_id": "NCT05754255",
      "title": "Comparison of High-flow Oxygen With or Without Nasal Positive Airway Pressure (PAP) During Propofol Sedation for Colonoscopy in an Ambulatory Surgical Center",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colonoscopy",
        "Positive-Pressure Respiration"
      ],
      "interventions": [
        {
          "name": "Nasal Cannula",
          "type": "DEVICE"
        },
        {
          "name": "Nasal Positive Airway Pressure System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2023-09",
      "completion_date": "2024-06-03",
      "has_results": false,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-09-06T12:24:06.675Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05754255"
    },
    {
      "nct_id": "NCT03700606",
      "title": "Physiological Changes With High-Flow Nasal Cannula",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome in Premature Infant"
      ],
      "interventions": [
        {
          "name": "High flow nasal cannula",
          "type": "PROCEDURE"
        },
        {
          "name": "Nasal CPAP",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Sharp HealthCare",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "23 Weeks",
        "maximum_age": "28 Weeks",
        "sex": "ALL",
        "summary": "23 Weeks to 28 Weeks"
      },
      "enrollment_count": 80,
      "start_date": "2019-03-15",
      "completion_date": "2022-02-14",
      "has_results": true,
      "last_update_posted_date": "2026-04-17",
      "last_synced_at": "2026-09-06T12:24:06.675Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03700606"
    },
    {
      "nct_id": "NCT04704375",
      "title": "Effects of Osteopathic Manipulative Treatment and Bio Electro-Magnetic Regulation Therapy on Low Back Pain in Adults.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Musculoskeletal Pain"
      ],
      "interventions": [
        {
          "name": "Bio Electro-Magnetic Regulation (BEMER) Therapy",
          "type": "DEVICE"
        },
        {
          "name": "OMT (osteopathic manipulative treatment)",
          "type": "PROCEDURE"
        },
        {
          "name": "Light touch",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Lake Erie College of Osteopathic Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 40,
      "start_date": "2018-09-13",
      "completion_date": "2019-09-09",
      "has_results": true,
      "last_update_posted_date": "2023-11-18",
      "last_synced_at": "2026-09-06T12:24:06.675Z",
      "location_count": 1,
      "location_summary": "Bradenton, Florida",
      "locations": [
        {
          "city": "Bradenton",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04704375"
    },
    {
      "nct_id": "NCT03511846",
      "title": "Pain Biomarker Study",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Migraine",
        "Cluster Headache",
        "Trigeminal Autonomic Cephalgia",
        "Hemicrania Continua",
        "Paroxysmal Hemicrania",
        "SUNCT",
        "Short-Lasting Unilateral Neuralgiform Headache With Conjunctival Injection and Tearing"
      ],
      "interventions": [
        {
          "name": "Oral capsaicin",
          "type": "DRUG"
        },
        {
          "name": "Topical capsaicin",
          "type": "DRUG"
        },
        {
          "name": "Intranasal capsaicin",
          "type": "DRUG"
        },
        {
          "name": "Cold Water Irrigation",
          "type": "OTHER"
        },
        {
          "name": "Medical Air",
          "type": "OTHER"
        },
        {
          "name": "Low Flow Oxygen",
          "type": "DRUG"
        },
        {
          "name": "High Flow Oxygen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 371,
      "start_date": "2018-03-21",
      "completion_date": "2028-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-18",
      "last_synced_at": "2026-09-06T12:24:06.675Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03511846"
    },
    {
      "nct_id": "NCT03745898",
      "title": "The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Heart Failure",
        "Central Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Oxygen",
          "type": "DRUG"
        },
        {
          "name": "Room Air",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 98,
      "start_date": "2019-04-15",
      "completion_date": "2022-06-17",
      "has_results": true,
      "last_update_posted_date": "2023-08-01",
      "last_synced_at": "2026-09-06T12:24:06.675Z",
      "location_count": 26,
      "location_summary": "Tucson, Arizona • Stanford, California • New Haven, Connecticut + 20 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03745898"
    }
  ]
}