{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Low+Frequency+Ultrasound+Therapy&page=2",
    "query": {
      "intervention": "Low Frequency Ultrasound Therapy",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 38,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Low+Frequency+Ultrasound+Therapy&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Low+Frequency+Ultrasound+Therapy&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-02T02:20:47.608Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03737318",
      "title": "Correcting Residual Errors With Spectral, Ultrasound, Traditional Speech Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Speech Sound Disorder"
      ],
      "interventions": [
        {
          "name": "Biofeedback-ultrasound",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Biofeedback--visual-acoustic",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Traditional articulation treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "New York University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "9 Years to 15 Years"
      },
      "enrollment_count": 108,
      "start_date": "2019-03-01",
      "completion_date": "2024-08-31",
      "has_results": true,
      "last_update_posted_date": "2026-01-05",
      "last_synced_at": "2026-10-02T02:20:47.608Z",
      "location_count": 2,
      "location_summary": "Bloomfield, New Jersey • Syracuse, New York",
      "locations": [
        {
          "city": "Bloomfield",
          "state": "New Jersey"
        },
        {
          "city": "Syracuse",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03737318"
    },
    {
      "nct_id": "NCT01200563",
      "title": "Comparative Effectiveness Study of MIST Therapy Versus Negative Pressure Wound Therapy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Wounds"
      ],
      "interventions": [
        {
          "name": "MIST Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Vacuum Assisted Closure",
          "type": "DEVICE"
        },
        {
          "name": "MIST Therapy and Negative Pressure Wound Therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Celleration, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2010-08",
      "completion_date": "2011-07",
      "has_results": false,
      "last_update_posted_date": "2014-12-15",
      "last_synced_at": "2026-10-02T02:20:47.608Z",
      "location_count": 1,
      "location_summary": "Mesa, Arizona",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01200563"
    },
    {
      "nct_id": "NCT05901610",
      "title": "Decision Making in Chronic Pain and Alcohol Use Disorder",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Use Disorder",
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Episodic Future Thinking",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Episodic Thinking",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low-intensity Focused Ultrasound",
          "type": "DEVICE"
        },
        {
          "name": "Sham Low-intensity Focused Ultrasound",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "Kirstin M Gatchalian",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2024-06-28",
      "completion_date": "2026-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-14",
      "last_synced_at": "2026-10-02T02:20:47.608Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05901610"
    },
    {
      "nct_id": "NCT01549860",
      "title": "Effects of Non Contact Low Frequency Ultrasound in Healing Venous Leg Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Insufficiency",
        "Venous Reflux",
        "Lower Extremity Ulcer"
      ],
      "interventions": [
        {
          "name": "MIST Therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Celleration, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 156,
      "start_date": "2012-04",
      "completion_date": "2015-04",
      "has_results": true,
      "last_update_posted_date": "2015-07-30",
      "last_synced_at": "2026-10-02T02:20:47.608Z",
      "location_count": 1,
      "location_summary": "Weymouth, Massachusetts",
      "locations": [
        {
          "city": "Weymouth",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01549860"
    },
    {
      "nct_id": "NCT04593875",
      "title": "LIFUP for Treatment of Motor Deficits in Parkinson's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "Active LIFUP Treatment",
          "type": "DEVICE"
        },
        {
          "name": "Sham LIFUP Treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 31,
      "start_date": "2022-06-15",
      "completion_date": "2024-07-31",
      "has_results": true,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-10-02T02:20:47.608Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04593875"
    },
    {
      "nct_id": "NCT07207122",
      "title": "Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "Gen0Bh Transcranial Focused Ultrasound System (Active)",
          "type": "DEVICE"
        },
        {
          "name": "Gen0Bh Transcranial Focused Ultrasound System (Sham)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sanmai Technologies PBC dba Sanmai",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "22 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2025-10-08",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-31",
      "last_synced_at": "2026-10-02T02:20:47.608Z",
      "location_count": 4,
      "location_summary": "Tucson, Arizona • Santa Monica, California • Gainesville, Florida + 1 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07207122"
    },
    {
      "nct_id": "NCT03347084",
      "title": "Deep Brain Stimulation with LIFUP for Mild Cognitive Impairment and Mild Alzheimer's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Brain Imaging",
        "Mild Cognitive Impairment",
        "Alzheimer Disease",
        "Deep Brain Stimulation"
      ],
      "interventions": [
        {
          "name": "Excitation",
          "type": "DEVICE"
        },
        {
          "name": "Inhibition",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2018-11-10",
      "completion_date": "2023-10-01",
      "has_results": false,
      "last_update_posted_date": "2024-09-05",
      "last_synced_at": "2026-10-02T02:20:47.608Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03347084"
    },
    {
      "nct_id": "NCT04391842",
      "title": "Sustained Acoustic Medicine (SAM) Combined With a Diclofenac Ultrasound Coupling Patch for Knee Osteoarthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Osteo Arthritis Knee",
        "Arthritis"
      ],
      "interventions": [
        {
          "name": "Sustained Acoustic Device with 1% Diclofenac patch",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "45 Years to 85 Years"
      },
      "enrollment_count": 34,
      "start_date": "2019-09-01",
      "completion_date": "2019-12-31",
      "has_results": true,
      "last_update_posted_date": "2023-06-27",
      "last_synced_at": "2026-10-02T02:20:47.608Z",
      "location_count": 1,
      "location_summary": "Dryden, New York",
      "locations": [
        {
          "city": "Dryden",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04391842"
    },
    {
      "nct_id": "NCT02756884",
      "title": "Safety and Preliminary Efficacy of Adipose Derived Stem Cells and Low Frequency Ultrasound in PAD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Peripheral Arterial Disease"
      ],
      "interventions": [
        {
          "name": "LoFU and aADSC",
          "type": "BIOLOGICAL"
        },
        {
          "name": "adipose derived stem cells",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Arkansas Heart Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 10,
      "start_date": "2015-06-03",
      "completion_date": "2019-01-31",
      "has_results": false,
      "last_update_posted_date": "2019-06-26",
      "last_synced_at": "2026-10-02T02:20:47.608Z",
      "location_count": 2,
      "location_summary": "Little Rock, Arkansas",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02756884"
    },
    {
      "nct_id": "NCT06813430",
      "title": "Non-Contact Low-Frequency Ultrasound Vs Standard LaLonde Protocol for Fingertip Injury Wound Healing",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non-contact Low Frequency Ultrasound",
        "Lalonde Protocol",
        "Fingertip Amputation"
      ],
      "interventions": [
        {
          "name": "Non-contact Low Frequency Ultrasound",
          "type": "DEVICE"
        },
        {
          "name": "Lalonde Protocol (standard of care)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "St. Luke's Hospital, Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2025-02-10",
      "completion_date": "2026-02",
      "has_results": false,
      "last_update_posted_date": "2025-05-15",
      "last_synced_at": "2026-10-02T02:20:47.608Z",
      "location_count": 1,
      "location_summary": "Bethlehem, Pennsylvania",
      "locations": [
        {
          "city": "Bethlehem",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06813430"
    }
  ]
}