{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Low+Fructose",
    "query": {
      "intervention": "Low Fructose"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 26,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Low+Fructose&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T20:56:59.257Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04994418",
      "title": "The Impact of Sodium and Fructose on Blood Pressure and Inflammation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Blood Pressure",
        "Inflammation"
      ],
      "interventions": [
        {
          "name": "Recommended sodium and low fructose diet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "High sodium and low fructose diet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "High sodium and high fructose diet",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Delaware",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 91,
      "start_date": "2021-04-01",
      "completion_date": "2024-04-15",
      "has_results": false,
      "last_update_posted_date": "2024-12-06",
      "last_synced_at": "2026-09-03T20:56:59.257Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04994418"
    },
    {
      "nct_id": "NCT03076684",
      "title": "Gender Differences in the Metabolic Effects of Uric Acid",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Hyperuricemia"
      ],
      "interventions": [
        {
          "name": "low-fructose diet",
          "type": "OTHER"
        },
        {
          "name": "Allopurinol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2017-03-03",
      "completion_date": "2019-03-13",
      "has_results": false,
      "last_update_posted_date": "2019-04-17",
      "last_synced_at": "2026-09-03T20:56:59.257Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03076684"
    },
    {
      "nct_id": "NCT03245645",
      "title": "FODMAP Reintroduction in Irritable Bowel Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Irritable Bowel Syndrome With Diarrhea",
        "Irritable Bowel Syndrome With Mixed Bowel Habits"
      ],
      "interventions": [
        {
          "name": "Dietary Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2017-03-24",
      "completion_date": "2023-06-30",
      "has_results": false,
      "last_update_posted_date": "2023-07-11",
      "last_synced_at": "2026-09-03T20:56:59.257Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03245645"
    },
    {
      "nct_id": "NCT00554216",
      "title": "Study of VI-0521 Compared to Placebo in Treatment of Obesity in Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "VI-0521",
          "type": "DRUG"
        },
        {
          "name": "Placebo matched phentermine/topiramate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "VIVUS LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 1267,
      "start_date": "2007-11",
      "completion_date": "2009-05",
      "has_results": true,
      "last_update_posted_date": "2012-09-10",
      "last_synced_at": "2026-09-03T20:56:59.257Z",
      "location_count": 5,
      "location_summary": "San Diego, California • Ridgefield, Connecticut • Durham, North Carolina + 2 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Ridgefield",
          "state": "Connecticut"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Toledo",
          "state": "Ohio"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00554216"
    },
    {
      "nct_id": "NCT01182766",
      "title": "New Treatment for Alcohol and Nicotine Dependence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Alcohol Dependence",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Low-Dose Topiramate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "High-Dose Topiramate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 236,
      "start_date": "2011-11-01",
      "completion_date": "2017-10-06",
      "has_results": true,
      "last_update_posted_date": "2025-10-31",
      "last_synced_at": "2026-09-03T20:56:59.257Z",
      "location_count": 4,
      "location_summary": "La Jolla, California • Houston, Texas • Charlottesville, Virginia + 1 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Charlottesville",
          "state": "Virginia"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01182766"
    },
    {
      "nct_id": "NCT01260272",
      "title": "Study of Raisins Versus Alternative Snacks on Cardiovascular Risk Factors In Generally Healthy Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Risk Factors"
      ],
      "interventions": [
        {
          "name": "Alternative Snack Comparator",
          "type": "OTHER"
        },
        {
          "name": "Raisins",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Louisville Metabolic and Atherosclerosis Research Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2010-12",
      "completion_date": "2011-09",
      "has_results": true,
      "last_update_posted_date": "2014-04-29",
      "last_synced_at": "2026-09-03T20:56:59.257Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01260272"
    },
    {
      "nct_id": "NCT02202876",
      "title": "Redox Imbalance and the Development of Cystic Fibrosis Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 2",
        "Cystic Fibrosis"
      ],
      "interventions": [
        {
          "name": "Oral Glucose Tolerance Test",
          "type": "OTHER"
        },
        {
          "name": "High Glycemic Index Meal",
          "type": "OTHER"
        },
        {
          "name": "Low Glycemic Index Meal",
          "type": "OTHER"
        },
        {
          "name": "Test Soda",
          "type": "OTHER"
        },
        {
          "name": "Fruit juice",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Year and older"
      },
      "enrollment_count": 34,
      "start_date": "2014-11",
      "completion_date": "2018-09-09",
      "has_results": false,
      "last_update_posted_date": "2020-06-04",
      "last_synced_at": "2026-09-03T20:56:59.257Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02202876"
    },
    {
      "nct_id": "NCT06146322",
      "title": "Barley Beta-glucan, Glycemic Control, and Appetite",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diet, Healthy",
        "Blood Sugar; High",
        "Diabetes",
        "Appetite and General Nutritional Disorders",
        "Appetitive Behavior"
      ],
      "interventions": [
        {
          "name": "WR",
          "type": "OTHER"
        },
        {
          "name": "LB",
          "type": "OTHER"
        },
        {
          "name": "MB",
          "type": "OTHER"
        },
        {
          "name": "HB",
          "type": "OTHER"
        },
        {
          "name": "WR+50g HFCS",
          "type": "OTHER"
        },
        {
          "name": "LB + 50 g HFCS",
          "type": "OTHER"
        },
        {
          "name": "MB + 50 g HFCS",
          "type": "OTHER"
        },
        {
          "name": "HB + 50 g HFCS",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Washington State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 16,
      "start_date": "2019-10-01",
      "completion_date": "2020-10-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-24",
      "last_synced_at": "2026-09-03T20:56:59.257Z",
      "location_count": 1,
      "location_summary": "Spokane, Washington",
      "locations": [
        {
          "city": "Spokane",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06146322"
    },
    {
      "nct_id": "NCT04168372",
      "title": "Fructose: Substrate, Stimulus, or Both?",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insulin Resistance",
        "Insulin Sensitivity",
        "Pre Diabetes"
      ],
      "interventions": [
        {
          "name": "High fructose, fructose labeled meal",
          "type": "OTHER"
        },
        {
          "name": "High fructose, pyruvate labeled meal",
          "type": "OTHER"
        },
        {
          "name": "Low fructose, fructose labeled meal",
          "type": "OTHER"
        },
        {
          "name": "Low fructose, pyruvate labeled meal",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Touro University, California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "20 Years to 55 Years"
      },
      "enrollment_count": 35,
      "start_date": "2019-09-15",
      "completion_date": "2027-07-20",
      "has_results": false,
      "last_update_posted_date": "2026-07-10",
      "last_synced_at": "2026-09-03T20:56:59.257Z",
      "location_count": 1,
      "location_summary": "Vallejo, California",
      "locations": [
        {
          "city": "Vallejo",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04168372"
    },
    {
      "nct_id": "NCT07209202",
      "title": "Fructose Intestinal Gluconeogenesis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Participants",
        "Obese But Otherwise Healthy Participants"
      ],
      "interventions": [
        {
          "name": "High fructose meal",
          "type": "OTHER"
        },
        {
          "name": "Low fructose meal",
          "type": "OTHER"
        },
        {
          "name": "13C labeled fructose, oral",
          "type": "OTHER"
        },
        {
          "name": "13C labeled fructose, intravenous",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Touro University, California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "20 Years to 55 Years"
      },
      "enrollment_count": 40,
      "start_date": "2026-03-02",
      "completion_date": "2030-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-06",
      "last_synced_at": "2026-09-03T20:56:59.257Z",
      "location_count": 1,
      "location_summary": "Vallejo, California",
      "locations": [
        {
          "city": "Vallejo",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07209202"
    }
  ]
}