{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Low+IOP",
    "query": {
      "intervention": "Low IOP"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 22,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Low+IOP&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-09T05:56:49.388Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05495555",
      "title": "The Cutting Efficiency of Hybrid Tips in Different Grades of Cataract",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cataract"
      ],
      "interventions": [
        {
          "name": "INTREPID® Hybrid tip",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cataract and Laser Institute of Southern Oregon",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2022-08-03",
      "completion_date": "2024-02-07",
      "has_results": true,
      "last_update_posted_date": "2025-03-11",
      "last_synced_at": "2026-09-09T05:56:49.388Z",
      "location_count": 1,
      "location_summary": "Medford, Oregon",
      "locations": [
        {
          "city": "Medford",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05495555"
    },
    {
      "nct_id": "NCT03469297",
      "title": "Early Feasibility Study of the Brown Glaucoma Implant in Patients With Severe Visual Impairment or No Light Perceived",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "Brown Glaucoma Implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "MicroOptx",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2018-05-01",
      "completion_date": "2021-09-20",
      "has_results": true,
      "last_update_posted_date": "2022-12-28",
      "last_synced_at": "2026-09-09T05:56:49.388Z",
      "location_count": 3,
      "location_summary": "Bloomington, Minnesota • Dayton, Ohio • Dallas, Texas",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Minnesota"
        },
        {
          "city": "Dayton",
          "state": "Ohio"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03469297"
    },
    {
      "nct_id": "NCT05254379",
      "title": "Transcranial Direct Current Stimulation Treatment for Warriors Experiencing Chronic Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Post Traumatic Stress Disorder (PTSD)",
        "Depression"
      ],
      "interventions": [
        {
          "name": "tDCS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 38,
      "start_date": "2022-03-02",
      "completion_date": "2025-05-31",
      "has_results": true,
      "last_update_posted_date": "2026-08-21",
      "last_synced_at": "2026-09-09T05:56:49.388Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05254379"
    },
    {
      "nct_id": "NCT05765201",
      "title": "Phacoemulsification at High IOP and Physiologic IOP: Impact on Anterior and Posterior Segment Physiology",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nuclear Cataract"
      ],
      "interventions": [
        {
          "name": "High IOP",
          "type": "OTHER"
        },
        {
          "name": "Low IOP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Matthew Rauen",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 27,
      "start_date": "2022-09-22",
      "completion_date": "2023-05-04",
      "has_results": false,
      "last_update_posted_date": "2024-01-08",
      "last_synced_at": "2026-09-09T05:56:49.388Z",
      "location_count": 1,
      "location_summary": "West Des Moines, Iowa",
      "locations": [
        {
          "city": "West Des Moines",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05765201"
    },
    {
      "nct_id": "NCT07223866",
      "title": "The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cataract and IOL Surgery",
        "Cataract Surgery Anesthesia",
        "Cataract Surgery Experience",
        "Nuclear Cataract"
      ],
      "interventions": [
        {
          "name": "High IOP Setting",
          "type": "DEVICE"
        },
        {
          "name": "Low IOP Setting",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Matthew Rauen",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 85,
      "start_date": "2025-11-01",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-09-09T05:56:49.388Z",
      "location_count": 1,
      "location_summary": "West Des Moines, Iowa",
      "locations": [
        {
          "city": "West Des Moines",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07223866"
    },
    {
      "nct_id": "NCT04360369",
      "title": "Comparison of Intraocular Pressure Measurements Between Reichert Tono-Vera Tonometer and Goldmann Tonometry",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intraocular Pressure",
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "IOP with Goldmann Applanation Tonometer",
          "type": "DEVICE"
        },
        {
          "name": "IOP with comparator ORA G3 and ic100 tonometers",
          "type": "DEVICE"
        },
        {
          "name": "IOP with Tono-Vera Tonometer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Reichert, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 61,
      "start_date": "2020-10-19",
      "completion_date": "2021-04-28",
      "has_results": false,
      "last_update_posted_date": "2022-01-03",
      "last_synced_at": "2026-09-09T05:56:49.388Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04360369"
    },
    {
      "nct_id": "NCT02628223",
      "title": "180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for Glaucoma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Open Angle Glaucoma",
        "Ocular Hypertension",
        "Glaucoma, Open Angle, Pseudo-exfoliative",
        "Pigment Dispersion Syndrome",
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "Selective Laser Trabeculoplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "Neodymium:Yttrium Aluminum Garnet (YAG) laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Temple University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 76,
      "start_date": "2014-09",
      "completion_date": "2017-12",
      "has_results": true,
      "last_update_posted_date": "2020-11-05",
      "last_synced_at": "2026-09-09T05:56:49.388Z",
      "location_count": 2,
      "location_summary": "Wilmington, Delaware • Thorndale, Pennsylvania",
      "locations": [
        {
          "city": "Wilmington",
          "state": "Delaware"
        },
        {
          "city": "Thorndale",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02628223"
    },
    {
      "nct_id": "NCT06325397",
      "title": "Less Discomfort and Less Pharmacology. Cataract Surgery at Physiologic Intraocular Pressure (IOP)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nuclear Cataract"
      ],
      "interventions": [
        {
          "name": "High Intraocular Pressure (IOP)",
          "type": "OTHER"
        },
        {
          "name": "Low Intraocular Pressure (IOP)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Matthew Rauen",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 65,
      "start_date": "2024-03-18",
      "completion_date": "2025-04-01",
      "has_results": false,
      "last_update_posted_date": "2025-05-21",
      "last_synced_at": "2026-09-09T05:56:49.388Z",
      "location_count": 1,
      "location_summary": "West Des Moines, Iowa",
      "locations": [
        {
          "city": "West Des Moines",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06325397"
    },
    {
      "nct_id": "NCT05162989",
      "title": "iCare HOME2 Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intraocular Pressure",
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "iCare HOME2 vs iCare IC200",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Icare Finland Oy",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 47,
      "start_date": "2021-11-26",
      "completion_date": "2021-12-15",
      "has_results": false,
      "last_update_posted_date": "2021-12-20",
      "last_synced_at": "2026-09-09T05:56:49.388Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05162989"
    },
    {
      "nct_id": "NCT06934577",
      "title": "Michigan Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (SIGHT) 2",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eye Diseases",
        "Visual Impairment",
        "Glaucoma"
      ],
      "interventions": [
        {
          "name": "Standard optometric examination",
          "type": "OTHER"
        },
        {
          "name": "Technology enhanced eye disease detection protocol",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 900,
      "start_date": "2025-12-04",
      "completion_date": "2030-08",
      "has_results": false,
      "last_update_posted_date": "2025-12-15",
      "last_synced_at": "2026-09-09T05:56:49.388Z",
      "location_count": 1,
      "location_summary": "Flint, Michigan",
      "locations": [
        {
          "city": "Flint",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06934577"
    }
  ]
}