{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lower+extremity+and%2For+upper+extremity+surgery",
    "query": {
      "intervention": "Lower extremity and/or upper extremity surgery"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 67,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lower+extremity+and%2For+upper+extremity+surgery&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T05:29:24.477Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05375071",
      "title": "BFR After Biceps Tendon Repair and MPFLR",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patellofemoral Joint Dislocation",
        "Bicep Tendon Rupture"
      ],
      "interventions": [
        {
          "name": "Blood Flow Restriction (BFR) Therapy",
          "type": "OTHER"
        },
        {
          "name": "Physical Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-07-29",
      "completion_date": "2025-07-29",
      "has_results": false,
      "last_update_posted_date": "2025-09-29",
      "last_synced_at": "2026-09-25T05:29:24.477Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05375071"
    },
    {
      "nct_id": "NCT01462448",
      "title": "Study to Identify the Genetic Variations Associated With Phantom Limb Pain",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Phantom Limb"
      ],
      "interventions": [
        {
          "name": "Blood Draw",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Henry M. Jackson Foundation for the Advancement of Military Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 726,
      "start_date": "2012-03",
      "completion_date": "2023-08-06",
      "has_results": false,
      "last_update_posted_date": "2025-08-12",
      "last_synced_at": "2026-09-25T05:29:24.477Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01462448"
    },
    {
      "nct_id": "NCT06520020",
      "title": "Evaluating Safety and Feasibility of Transcutaneous Spinal Cord Stimulation Following Traumatic and Non-Traumatic Spinal Cord Injury: A Pilot Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Stimulation",
        "Electric Stimulation Therapy",
        "Traumatic Spinal Cord Injury",
        "Cervical Myelopathy"
      ],
      "interventions": [
        {
          "name": "Transcutaneous Spinal Cord Stimulation (Tc-SCS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Francis Farhadi",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2024-10-23",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-07",
      "last_synced_at": "2026-09-25T05:29:24.477Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06520020"
    },
    {
      "nct_id": "NCT00142532",
      "title": "Acupuncture for Post-Thoracotomy Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Lung Cancer",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Acupuncture and Questionnaires",
          "type": "PROCEDURE"
        },
        {
          "name": "Placebo Acupuncture, Questionnaires",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 162,
      "start_date": "2005-06",
      "completion_date": "2008-01",
      "has_results": false,
      "last_update_posted_date": "2009-01-14",
      "last_synced_at": "2026-09-25T05:29:24.477Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00142532"
    },
    {
      "nct_id": "NCT01073020",
      "title": "Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes Mellitus",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Allergan Adjustable Gastric Band Surgery",
          "type": "DEVICE"
        },
        {
          "name": "Intensive Medical Diabetes & Weight Management (Why WAIT) - Band Group",
          "type": "OTHER"
        },
        {
          "name": "Roux-en-Y Gastric Bypass (RYGB) Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Intensive Medical Diabetes & Weight Management (Why WAIT) - Bypass Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Joslin Diabetes Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 88,
      "start_date": "2010-01",
      "completion_date": "2016-11",
      "has_results": true,
      "last_update_posted_date": "2021-06-28",
      "last_synced_at": "2026-09-25T05:29:24.477Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01073020"
    },
    {
      "nct_id": "NCT00386724",
      "title": "Effectiveness of Precision Spinal Cord Stimulation With Artisan Paddle Electrode",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Back Pain",
        "Chronic Pain",
        "Pain in Leg, Unspecified"
      ],
      "interventions": [
        {
          "name": "Precision Spinal Cord Stimulation System",
          "type": "DEVICE"
        },
        {
          "name": "Artisan Surgical Lead",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2006-10",
      "completion_date": "2008-08",
      "has_results": true,
      "last_update_posted_date": "2020-12-17",
      "last_synced_at": "2026-09-25T05:29:24.477Z",
      "location_count": 2,
      "location_summary": "Charleston, South Carolina • Norfolk, Virginia",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        },
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00386724"
    },
    {
      "nct_id": "NCT07227649",
      "title": "NAC-REPAIR for Post-surgical Pain",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Carpal Tunnel Surgery",
        "Trigger Finger Disorder",
        "De Quervain Syndrome",
        "Guyon's Canal",
        "Dupuytren Contracture",
        "Morton Neuroma",
        "Tarsal Tunnel Syndrome",
        "Plantar Fasciopathy",
        "Peroneal Nerve Entrapment"
      ],
      "interventions": [
        {
          "name": "NAC",
          "type": "DRUG"
        },
        {
          "name": "NAC 0mg/day (Placebo)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 80,
      "start_date": "2026-10-15",
      "completion_date": "2027-07-15",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-09-25T05:29:24.477Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07227649"
    },
    {
      "nct_id": "NCT03973957",
      "title": "Talc Outpatient Pleurodesis With Indwelling Catheter",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pleural Effusion",
        "Pleural Diseases",
        "Malignant Pleural Effusion"
      ],
      "interventions": [
        {
          "name": "Indwelling pleural catheter placement",
          "type": "DEVICE"
        },
        {
          "name": "Fentanyl Citrate",
          "type": "DRUG"
        },
        {
          "name": "Talc Slurry",
          "type": "DRUG"
        },
        {
          "name": "Drainage collection bag",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "The Cooper Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 124,
      "start_date": "2019-05-27",
      "completion_date": "2021-01-31",
      "has_results": false,
      "last_update_posted_date": "2019-06-04",
      "last_synced_at": "2026-09-25T05:29:24.477Z",
      "location_count": 1,
      "location_summary": "Camden, New Jersey",
      "locations": [
        {
          "city": "Camden",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03973957"
    },
    {
      "nct_id": "NCT02440295",
      "title": "Pilot Study to Assess the Use of Spy Elite for Assessment of Amputation Healing",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Wound Healing",
        "Lower Extremity Amputation",
        "Above Knee Amputation",
        "Below Knee Amputation"
      ],
      "interventions": [
        {
          "name": "Lower Extremity Amputation",
          "type": "PROCEDURE"
        },
        {
          "name": "SPY Elite Imaging System",
          "type": "DEVICE"
        },
        {
          "name": "Indocyaine Green",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Corewell Health West",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2015-05",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2023-09-28",
      "last_synced_at": "2026-09-25T05:29:24.477Z",
      "location_count": 1,
      "location_summary": "Grand Rapids, Michigan",
      "locations": [
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02440295"
    },
    {
      "nct_id": "NCT04360421",
      "title": "Use of Long-acting Bupivacaine In Lower Extremity Amputation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Amputation",
        "Anesthesia, Local",
        "Opioid Use"
      ],
      "interventions": [
        {
          "name": "Liposomal bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2020-04-21",
      "completion_date": "2023-08-01",
      "has_results": false,
      "last_update_posted_date": "2023-08-22",
      "last_synced_at": "2026-09-25T05:29:24.477Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04360421"
    }
  ]
}