{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lower-Fat+Diet&page=2",
    "query": {
      "intervention": "Lower-Fat Diet",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 60,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lower-Fat+Diet&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lower-Fat+Diet&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-30T12:17:17.217Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00548782",
      "title": "Paleolithic Diets vs T2D and Improvements in the Metabolic Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Paleolithic diet",
          "type": "OTHER"
        },
        {
          "name": "ADA ( American Diabetes Association) recommended diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2007-09",
      "completion_date": "2016-09",
      "has_results": false,
      "last_update_posted_date": "2020-02-28",
      "last_synced_at": "2026-09-30T12:17:17.217Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00548782"
    },
    {
      "nct_id": "NCT06395181",
      "title": "Whole Food Plant-based Diet Effect on Obstructive Sleep Apnea",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Daytime Sleepiness"
      ],
      "interventions": [
        {
          "name": "Whole Food Plant-Based Diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 9,
      "start_date": "2024-05-14",
      "completion_date": "2026-07-21",
      "has_results": false,
      "last_update_posted_date": "2026-07-22",
      "last_synced_at": "2026-09-30T12:17:17.217Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06395181"
    },
    {
      "nct_id": "NCT06730633",
      "title": "Collaborate and Leverage Evidence in African American Rural Network",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Diseases"
      ],
      "interventions": [
        {
          "name": "Heart Matters",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 173,
      "start_date": "2025-02-22",
      "completion_date": "2026-08-17",
      "has_results": false,
      "last_update_posted_date": "2026-08-28",
      "last_synced_at": "2026-09-30T12:17:17.217Z",
      "location_count": 9,
      "location_summary": "Enfield, North Carolina • Nashville, North Carolina • Rocky Mount, North Carolina + 3 more",
      "locations": [
        {
          "city": "Enfield",
          "state": "North Carolina"
        },
        {
          "city": "Nashville",
          "state": "North Carolina"
        },
        {
          "city": "Rocky Mount",
          "state": "North Carolina"
        },
        {
          "city": "Rocky Mount",
          "state": "North Carolina"
        },
        {
          "city": "Rocky Mount",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06730633"
    },
    {
      "nct_id": "NCT03454828",
      "title": "Mechanisms of Obesity and Its Metabolic Complications in Youth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity, Childhood"
      ],
      "interventions": [
        {
          "name": "obese carbohydrate diet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "lean carbohydrate diet",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "15 Years to 21 Years"
      },
      "enrollment_count": 38,
      "start_date": "2018-08-18",
      "completion_date": "2024-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-10-09",
      "last_synced_at": "2026-09-30T12:17:17.217Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03454828"
    },
    {
      "nct_id": "NCT00847574",
      "title": "The WORLD (Weight Optimization: Revamping Lifestyles Using the Dietary Guidelines) Study - Developing, Implementing, and Testing an Education Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Cardiovascular Disease"
      ],
      "interventions": [
        {
          "name": "Moderate-fat",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lower-fat",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 50 Years · Female only"
      },
      "enrollment_count": 101,
      "start_date": "2006-03",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2023-08-18",
      "last_synced_at": "2026-09-30T12:17:17.217Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00847574"
    },
    {
      "nct_id": "NCT00422630",
      "title": "The Metabolic Effects of Different Weight Loss Diets",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome X",
        "Obesity",
        "Insulin Resistance",
        "Hypertension",
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "The DASH diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "The low glycemic Index Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Reduced calorie American Diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rockefeller University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 18,
      "start_date": "2007-10",
      "completion_date": "2010-02",
      "has_results": false,
      "last_update_posted_date": "2011-10-13",
      "last_synced_at": "2026-09-30T12:17:17.217Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00422630"
    },
    {
      "nct_id": "NCT03454347",
      "title": "The Efficacy of Protein Supplementation on Attenuating Muscle Atrophy Following Disuse in the Collegiate Population",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Disuse Atrophy"
      ],
      "interventions": [
        {
          "name": "Profile Perform",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Lower Limb Suspension",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "South Dakota State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "18 Years to 25 Years"
      },
      "enrollment_count": 32,
      "start_date": "2018-02-22",
      "completion_date": "2022-05-10",
      "has_results": false,
      "last_update_posted_date": "2023-02-08",
      "last_synced_at": "2026-09-30T12:17:17.217Z",
      "location_count": 1,
      "location_summary": "Brookings, South Dakota",
      "locations": [
        {
          "city": "Brookings",
          "state": "South Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03454347"
    },
    {
      "nct_id": "NCT02282423",
      "title": "PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Pre-study dietary and exercise instruction.",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Screening examination and oral glucose tolerance test",
          "type": "PROCEDURE"
        },
        {
          "name": "Euglycemic clamp",
          "type": "PROCEDURE"
        },
        {
          "name": "VO2max.",
          "type": "PROCEDURE"
        },
        {
          "name": "Acute exercise bout",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Percutaneous needle muscle biopsies",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "59 Years",
        "sex": "ALL",
        "summary": "30 Years to 59 Years"
      },
      "enrollment_count": 26,
      "start_date": "2014-05",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-05-12",
      "last_synced_at": "2026-09-30T12:17:17.217Z",
      "location_count": 1,
      "location_summary": "Scottsdale, Arizona",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02282423"
    },
    {
      "nct_id": "NCT00198913",
      "title": "Long Term Free Living Study With Modified Foods and Type 2 Diabetics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes Mellitus",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "lower fat food supplied and education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "gift cards for grocery foods and written education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins Bloomberg School of Public Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2002-06",
      "completion_date": "2003-02",
      "has_results": false,
      "last_update_posted_date": "2005-09-20",
      "last_synced_at": "2026-09-30T12:17:17.217Z",
      "location_count": 1,
      "location_summary": "Lutherville, Maryland",
      "locations": [
        {
          "city": "Lutherville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00198913"
    },
    {
      "nct_id": "NCT02244814",
      "title": "Trial of Diet in Gestational Diabetes Mellitus: Metabolic Consequences to Mother and Offspring",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gestational Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Low Carbohydrate/Conventional",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Choosing Healthy Options in Carbohydrate Energy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "36 Years",
        "sex": "ALL",
        "summary": "Up to 36 Years"
      },
      "enrollment_count": 105,
      "start_date": "2015-07",
      "completion_date": "2020-11",
      "has_results": false,
      "last_update_posted_date": "2020-12-19",
      "last_synced_at": "2026-09-30T12:17:17.217Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02244814"
    }
  ]
}