{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lower-fat&page=2",
    "query": {
      "intervention": "Lower-fat",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lower-fat&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-17T01:49:41.598Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03837405",
      "title": "(R33 Phase) DELISH Study: Diabetes Education to Lower Insulin, Sugars, and Hunger",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Carbohydrate-restricted diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mindfuless",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 125,
      "start_date": "2018-12-12",
      "completion_date": "2021-06-17",
      "has_results": true,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-09-17T01:49:41.598Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03837405"
    },
    {
      "nct_id": "NCT04286555",
      "title": "Dietary Approaches to Stop Hypertension for Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 2",
        "Diabetes",
        "Diabetes type2",
        "Type2 Diabetes",
        "Type 2 Diabetes",
        "Type II Diabetes",
        "Hypertension",
        "High Blood Pressure"
      ],
      "interventions": [
        {
          "name": "DASH4D diet",
          "type": "OTHER"
        },
        {
          "name": "comparison diet",
          "type": "OTHER"
        },
        {
          "name": "higher sodium",
          "type": "OTHER"
        },
        {
          "name": "lower sodium",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 105,
      "start_date": "2021-06-02",
      "completion_date": "2024-06-17",
      "has_results": true,
      "last_update_posted_date": "2026-05-13",
      "last_synced_at": "2026-09-17T01:49:41.598Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04286555"
    },
    {
      "nct_id": "NCT05639556",
      "title": "Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cystic Fibrosis"
      ],
      "interventions": [
        {
          "name": "BMI and lean mass index from DXA",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Anthropometric Measurements",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hand-grip strength",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Six-minute walk Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sit-to-Stand Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Short physical performance battery (SPPB)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "BIA Sub-study",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Accelerometry to assess physical activity",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Gastrointestinal (GI) and nutrition questionnaires:",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: PHQ-8",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: GAD-7",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: The Treatment Self-Regulation Questionnaire (TSRQ)",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: CF Fatalism Scale",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: Body Esteem Scale for Adolescents and Adults (BESAA)",
          "type": "OTHER"
        },
        {
          "name": "12-month Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Oral glucose tolerance testing (OGTT)",
          "type": "OTHER"
        },
        {
          "name": "Continuous glucose monitoring (CGM)",
          "type": "DEVICE"
        },
        {
          "name": "Chest CT scans (When available within the past 6 months in medical records)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hologic Dual X-Ray Absorptiometry (DXA)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Ultrasound Sub-study of assessment of appendage muscles using ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Psychosocial questionnaire: Hunger Vital Sign questionnaire",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Respiratory symptom questionnaire: CRISS",
          "type": "OTHER"
        },
        {
          "name": "Spirometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Psychosocial questionnaire: Additional Health Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "CF Management Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Food Frequency Questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2023-04-20",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-13",
      "last_synced_at": "2026-09-17T01:49:41.598Z",
      "location_count": 23,
      "location_summary": "Tucson, Arizona • Little Rock, Arkansas • Atlanta, Georgia + 19 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05639556"
    },
    {
      "nct_id": "NCT01882881",
      "title": "Effects of Polyphenolic-rich Dark Chocolate/Cocoa and Almonds on Cardiovascular Disease Risk Factors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Disease"
      ],
      "interventions": [
        {
          "name": "Healthy American Control Diet",
          "type": "OTHER"
        },
        {
          "name": "Dark Chocolate/Cocoa Diet",
          "type": "OTHER"
        },
        {
          "name": "Almond Diet",
          "type": "OTHER"
        },
        {
          "name": "Dark Chocolate/Cocoa + Almond Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "30 Years to 70 Years"
      },
      "enrollment_count": 48,
      "start_date": "2012-03",
      "completion_date": "2016-08",
      "has_results": false,
      "last_update_posted_date": "2023-08-21",
      "last_synced_at": "2026-09-17T01:49:41.598Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01882881"
    },
    {
      "nct_id": "NCT01597531",
      "title": "Combinatorial Therapy for Peristent Type 2 Diabetes After Gastric Banding",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Type 2 Diabetes",
        "Gastric Banding"
      ],
      "interventions": [
        {
          "name": "Liraglutide",
          "type": "DRUG"
        },
        {
          "name": "Orlistat",
          "type": "DRUG"
        },
        {
          "name": "Liraglutide + Orlistat",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "East Carolina University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "25 Years to 70 Years"
      },
      "enrollment_count": 1,
      "start_date": "2012-06",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2018-02-05",
      "last_synced_at": "2026-09-17T01:49:41.598Z",
      "location_count": 1,
      "location_summary": "Greenville, North Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01597531"
    },
    {
      "nct_id": "NCT04763772",
      "title": "Clinical Effectiveness of Body Fat Distribution Imaging in Real-World Practice: The BODY-REAL Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight and Obesity",
        "PreDiabetes",
        "Type 2 Diabetes",
        "Cardiovascular Risk Factor"
      ],
      "interventions": [
        {
          "name": "Body Fat Distribution Imaging Report",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Basic Weight Information",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Patient Provided",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Physician Provided",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "BEHAVIORAL"
      ],
      "sponsor": "University Hospitals Cleveland Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "35 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2021-11-01",
      "completion_date": "2024-07-31",
      "has_results": true,
      "last_update_posted_date": "2025-03-25",
      "last_synced_at": "2026-09-17T01:49:41.598Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04763772"
    },
    {
      "nct_id": "NCT06395181",
      "title": "Whole Food Plant-based Diet Effect on Obstructive Sleep Apnea",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Daytime Sleepiness"
      ],
      "interventions": [
        {
          "name": "Whole Food Plant-Based Diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 9,
      "start_date": "2024-05-14",
      "completion_date": "2026-07-21",
      "has_results": false,
      "last_update_posted_date": "2026-07-22",
      "last_synced_at": "2026-09-17T01:49:41.598Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06395181"
    },
    {
      "nct_id": "NCT01817400",
      "title": "Mediators of Abnormal Reproductive Function in Obesity (MARO)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Infertility, Female",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Microdialysis",
          "type": "OTHER"
        },
        {
          "name": "Vascepa - Fish Oil",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Aspirin",
          "type": "DRUG"
        },
        {
          "name": "Pioglitazone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIETARY_SUPPLEMENT",
        "DRUG"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2013-03",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2015-03-17",
      "last_synced_at": "2026-09-17T01:49:41.598Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01817400"
    },
    {
      "nct_id": "NCT01975363",
      "title": "Pilot Study of Curcumin for Women With Obesity and High Risk for Breast Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atypical Ductal Breast Hyperplasia",
        "BRCA1 Gene Mutation",
        "BRCA2 Gene Mutation",
        "Ductal Breast Carcinoma in Situ",
        "Lobular Breast Carcinoma in Situ"
      ],
      "interventions": [
        {
          "name": "curcumin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Biomarker analysis",
          "type": "OTHER"
        },
        {
          "name": "Assessment of Dietary Intake",
          "type": "OTHER"
        },
        {
          "name": "Daily Log",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Ohio State University Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "19 Years and older · Female only"
      },
      "enrollment_count": 29,
      "start_date": "2013-06",
      "completion_date": "2016-09-19",
      "has_results": false,
      "last_update_posted_date": "2019-08-30",
      "last_synced_at": "2026-09-17T01:49:41.598Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01975363"
    },
    {
      "nct_id": "NCT00422630",
      "title": "The Metabolic Effects of Different Weight Loss Diets",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome X",
        "Obesity",
        "Insulin Resistance",
        "Hypertension",
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "The DASH diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "The low glycemic Index Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Reduced calorie American Diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rockefeller University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 18,
      "start_date": "2007-10",
      "completion_date": "2010-02",
      "has_results": false,
      "last_update_posted_date": "2011-10-13",
      "last_synced_at": "2026-09-17T01:49:41.598Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00422630"
    }
  ]
}