{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lower-functioning+older+adults&page=2",
    "query": {
      "intervention": "Lower-functioning older adults",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Lower-functioning+older+adults&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-28T21:22:58.153Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06341023",
      "title": "Functional Balance Intervention in Multiple Sclerosis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Functional Balance Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stretching",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 120,
      "start_date": "2025-01-21",
      "completion_date": "2027-07-09",
      "has_results": false,
      "last_update_posted_date": "2026-07-06",
      "last_synced_at": "2026-09-28T21:22:58.153Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06341023"
    },
    {
      "nct_id": "NCT05462977",
      "title": "Rhythmically Entrained Exercise in Community-Dwelling Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exercise",
        "Gait",
        "Cognitive Decline",
        "Caregiver Burden",
        "Cognitive Impairment",
        "Dementia",
        "Alzheimer Disease",
        "Mild Cognitive Impairment",
        "Respite Care",
        "Mental Health",
        "Depression",
        "Music Therapy",
        "Psychosocial Intervention",
        "Cognition",
        "Geriatric Assessment",
        "Cognitive Dysfunction",
        "Cognitive Aging",
        "Outcome Assessment, Health Care",
        "Balance",
        "Fall",
        "Walking",
        "Affect",
        "Physical Exertion",
        "Memory Deficit",
        "Memory Disorders",
        "Memory Impairment",
        "Neuropsychological Tests",
        "Executive Function",
        "Middle Aged",
        "Healthy Aging",
        "Elderly"
      ],
      "interventions": [
        {
          "name": "Group exercise program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Greensboro",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "55 Years to 99 Years"
      },
      "enrollment_count": 18,
      "start_date": "2022-05-01",
      "completion_date": "2023-09-30",
      "has_results": false,
      "last_update_posted_date": "2023-11-02",
      "last_synced_at": "2026-09-28T21:22:58.153Z",
      "location_count": 1,
      "location_summary": "Greensboro, North Carolina",
      "locations": [
        {
          "city": "Greensboro",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05462977"
    },
    {
      "nct_id": "NCT04589845",
      "title": "Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Solid Tumors"
      ],
      "interventions": [
        {
          "name": "Entrectinib",
          "type": "DRUG"
        },
        {
          "name": "Alectinib",
          "type": "DRUG"
        },
        {
          "name": "Atezolizumab",
          "type": "DRUG"
        },
        {
          "name": "Ipatasertib",
          "type": "DRUG"
        },
        {
          "name": "Trastuzumab emtansine",
          "type": "DRUG"
        },
        {
          "name": "Inavolisib",
          "type": "DRUG"
        },
        {
          "name": "Belvarafenib",
          "type": "DRUG"
        },
        {
          "name": "Pralsetinib",
          "type": "DRUG"
        },
        {
          "name": "Divarasib",
          "type": "DRUG"
        },
        {
          "name": "Camonsertib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hoffmann-La Roche",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 920,
      "start_date": "2021-01-18",
      "completion_date": "2032-09-25",
      "has_results": false,
      "last_update_posted_date": "2026-09-04",
      "last_synced_at": "2026-09-28T21:22:58.153Z",
      "location_count": 32,
      "location_summary": "Goodyear, Arizona • Los Angeles, California • Newport Beach, California + 25 more",
      "locations": [
        {
          "city": "Goodyear",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04589845"
    },
    {
      "nct_id": "NCT06910267",
      "title": "Leveraging Adult Protective Service Interaction to Offer Evidence-Based Treatment for Depression in Elder Neglect/Self Neglect",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression in Old Age"
      ],
      "interventions": [
        {
          "name": "APS Treatment as Usual",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Intervention-Behavioral Activation (BA)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2026-05-15",
      "completion_date": "2027-01-24",
      "has_results": false,
      "last_update_posted_date": "2026-06-30",
      "last_synced_at": "2026-09-28T21:22:58.153Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06910267"
    },
    {
      "nct_id": "NCT02132715",
      "title": "KAATSU Training to Enhance Physical Function of Older Adults With Osteoarthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Resistance Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "KAATSU exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2014-09",
      "completion_date": "2016-07",
      "has_results": false,
      "last_update_posted_date": "2016-08-23",
      "last_synced_at": "2026-09-28T21:22:58.153Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02132715"
    },
    {
      "nct_id": "NCT06976060",
      "title": "High-Intensity Interval Training in a Community Gym",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Age-related Strength Loss"
      ],
      "interventions": [
        {
          "name": "High-Intensity Interval Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Creighton University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "50 Years to 95 Years"
      },
      "enrollment_count": 6,
      "start_date": "2025-06-03",
      "completion_date": "2025-08-07",
      "has_results": false,
      "last_update_posted_date": "2025-09-22",
      "last_synced_at": "2026-09-28T21:22:58.153Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06976060"
    },
    {
      "nct_id": "NCT06396247",
      "title": "Impact of Brief Daily Functional Resistance Training on Lower Extremity Physical Performance",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Mobility Limitation"
      ],
      "interventions": [
        {
          "name": "Functional Activity Strength Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 360,
      "start_date": "2025-04-09",
      "completion_date": "2028-09",
      "has_results": false,
      "last_update_posted_date": "2026-07-22",
      "last_synced_at": "2026-09-28T21:22:58.153Z",
      "location_count": 2,
      "location_summary": "Hershey, Pennsylvania • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06396247"
    },
    {
      "nct_id": "NCT06959277",
      "title": "Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peripheral Neuropathies",
        "Peripheral Neuropathy Due to Chemotherapy",
        "Peripheral Neuropathy With Type 2 Diabetes",
        "Balance Control in Elderly",
        "Gait Disorders"
      ],
      "interventions": [
        {
          "name": "Walkasins",
          "type": "DEVICE"
        },
        {
          "name": "Fall Prevention Training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "RxFunction Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2025-06-17",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-14",
      "last_synced_at": "2026-09-28T21:22:58.153Z",
      "location_count": 6,
      "location_summary": "Mesa, Arizona • Boston, Massachusetts • Saint Paul, Minnesota + 3 more",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Saint Paul",
          "state": "Minnesota"
        },
        {
          "city": "Amherst",
          "state": "New York"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06959277"
    },
    {
      "nct_id": "NCT03074643",
      "title": "Utilizing Protein During Weight Loss to Impact Physical Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Weight Loss",
        "Diet Modification",
        "Aging",
        "Weight Change, Body",
        "Dietary Habits"
      ],
      "interventions": [
        {
          "name": "Weight loss intervention months 0-6",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exercise intervention months 0-6",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Carbohydrate supplement for months 0-6",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Protein supplement for months 0-6",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Protein supplement for follow-up months 7-18",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 187,
      "start_date": "2017-05-03",
      "completion_date": "2022-04-28",
      "has_results": true,
      "last_update_posted_date": "2023-05-22",
      "last_synced_at": "2026-09-28T21:22:58.153Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03074643"
    },
    {
      "nct_id": "NCT04996719",
      "title": "Effect of Rapamycin to Improve Cardiac Function in Frail Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Rapamune",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "60 Years to 99 Years"
      },
      "enrollment_count": 24,
      "start_date": "2022-05-24",
      "completion_date": "2023-08-25",
      "has_results": false,
      "last_update_posted_date": "2023-09-28",
      "last_synced_at": "2026-09-28T21:22:58.153Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04996719"
    }
  ]
}