{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Luprolide", "query": { "intervention": "Luprolide" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 45, "total_pages": 5, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Luprolide&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-02T11:15:06.745Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02903368", "title": "Neoadjuvant And Adjuvant Abiraterone Acetate + Apalutamide Prostate Cancer Undergoing Prostatectomy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Prostate Cancer" ], "interventions": [ { "name": "Apalutamide", "type": "DRUG" }, { "name": "Leuprolide", "type": "DRUG" }, { "name": "Prednisone", "type": "DRUG" }, { "name": "Abiraterone Acetate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Dana-Farber Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 118, "start_date": "2016-10-19", "completion_date": "2024-07-10", "has_results": true, "last_update_posted_date": "2025-06-13", "last_synced_at": "2026-09-02T11:15:06.745Z", "location_count": 4, "location_summary": "La Jolla, California • Boston, Massachusetts • New York, New York", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02903368" }, { "nct_id": "NCT00005044", "title": "Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Prostate Cancer" ], "interventions": [ { "name": "Casodex", "type": "DRUG" }, { "name": "Eulexin", "type": "DRUG" }, { "name": "LHRH agonist", "type": "DRUG" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "Radiation Therapy Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "MALE", "summary": "18 Years to 120 Years · Male only" }, "enrollment_count": 1579, "start_date": "2000-02", "completion_date": "2022-05-20", "has_results": true, "last_update_posted_date": "2022-06-15", "last_synced_at": "2026-09-02T11:15:06.745Z", "location_count": 241, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 181 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Montgomery", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT00005044" }, { "nct_id": "NCT06059118", "title": "Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Prostate Cancer" ], "interventions": [ { "name": "DFMO", "type": "DRUG" }, { "name": "testosterone cypionate", "type": "DRUG" }, { "name": "Luteinizing hormone-releasing hormone (LHRH) analogue", "type": "DRUG" }, { "name": "Enzalutamide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 50, "start_date": "2023-10-04", "completion_date": "2029-11-30", "has_results": false, "last_update_posted_date": "2026-01-14", "last_synced_at": "2026-09-02T11:15:06.745Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT06059118" }, { "nct_id": "NCT00170157", "title": "Hormone Therapy and Ipilimumab in Treating Patients With Advanced Prostate Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Prostate Adenocarcinoma", "Prostate Carcinoma", "Recurrent Prostate Carcinoma", "Stage III Prostate Cancer", "Stage IV Prostate Cancer" ], "interventions": [ { "name": "Bicalutamide", "type": "DRUG" }, { "name": "Flutamide", "type": "DRUG" }, { "name": "Goserelin Acetate", "type": "DRUG" }, { "name": "Ipilimumab", "type": "DRUG" }, { "name": "Leuprolide Acetate", "type": "DRUG" }, { "name": "Pharmacological Study", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 112, "start_date": "2004-06", "completion_date": "2013-06", "has_results": true, "last_update_posted_date": "2017-05-15", "last_synced_at": "2026-09-02T11:15:06.745Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00170157" }, { "nct_id": "NCT05873192", "title": "Presurgical Phase II Study of Talazoparib in Combination With Enzalutamide in Prostate Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Prostate Cancer" ], "interventions": [ { "name": "ADT", "type": "DRUG" }, { "name": "Enzalutamide", "type": "DRUG" }, { "name": "Talazoparib", "type": "DRUG" }, { "name": "Degarelix", "type": "DRUG" }, { "name": "Luprolide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 30, "start_date": "2025-06-03", "completion_date": "2028-12-31", "has_results": false, "last_update_posted_date": "2026-06-12", "last_synced_at": "2026-09-02T11:15:06.745Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05873192" }, { "nct_id": "NCT04734730", "title": "Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Castration-Sensitive Prostate Carcinoma", "Metastatic Prostate Adenocarcinoma", "Stage IV Prostate Cancer AJCC v8", "Stage IVA Prostate Cancer AJCC v8", "Stage IVB Prostate Cancer AJCC v8" ], "interventions": [ { "name": "Abiraterone Acetate", "type": "DRUG" }, { "name": "Bicalutamide", "type": "DRUG" }, { "name": "Degarelix", "type": "DRUG" }, { "name": "Goserelin Acetate", "type": "DRUG" }, { "name": "Leuprolide Acetate", "type": "DRUG" }, { "name": "Prednisone", "type": "DRUG" }, { "name": "Questionnaire Administration", "type": "OTHER" }, { "name": "Talazoparib", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "City of Hope Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 70, "start_date": "2021-05-04", "completion_date": "2027-08-23", "has_results": false, "last_update_posted_date": "2026-01-28", "last_synced_at": "2026-09-02T11:15:06.745Z", "location_count": 1, "location_summary": "Duarte, California", "locations": [ { "city": "Duarte", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04734730" }, { "nct_id": "NCT02319837", "title": "Safety and Efficacy Study of Enzalutamide Plus Leuprolide in Patients With Nonmetastatic Prostate Cancer (EMBARK)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hormone Sensitive Prostate Cancer", "Prostate Cancer", "Cancer of the Prostate" ], "interventions": [ { "name": "Enzalutamide", "type": "DRUG" }, { "name": "Placebo (No longer applicable in Open Label study period)", "type": "DRUG" }, { "name": "Leuprolide Open Label", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 1068, "start_date": "2014-12-17", "completion_date": "2026-09-19", "has_results": true, "last_update_posted_date": "2026-07-09", "last_synced_at": "2026-09-02T11:15:06.745Z", "location_count": 77, "location_summary": "Birmingham, Alabama • Anchorage, Alaska • Tucson, Arizona + 49 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02319837" }, { "nct_id": "NCT01344564", "title": "Initiation of Androgen Deprivation Therapy for Prostate Cancer Using Degarelix Followed by Leuprolide", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Prostate Cancer" ], "interventions": [ { "name": "Degarelix acetate, Leuprolide acetate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Urology of Virginia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 50, "start_date": "2011-04", "completion_date": "2012-08", "has_results": false, "last_update_posted_date": "2013-03-18", "last_synced_at": "2026-09-02T11:15:06.745Z", "location_count": 1, "location_summary": "Virginia Beach, Virginia", "locations": [ { "city": "Virginia Beach", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01344564" }, { "nct_id": "NCT04447872", "title": "The LUTEAL Trial: Luteal Stimulation vs. Estrogen Priming Protocol", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Infertility", "Diminished Ovarian Reserve", "IVF" ], "interventions": [ { "name": "Timing of injectable gonadotropins", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Northwell Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "20 Years", "maximum_age": "45 Years", "sex": "FEMALE", "summary": "20 Years to 45 Years · Female only" }, "enrollment_count": 142, "start_date": "2020-09-15", "completion_date": "2025-06", "has_results": false, "last_update_posted_date": "2023-10-16", "last_synced_at": "2026-09-02T11:15:06.745Z", "location_count": 1, "location_summary": "Manhasset, New York", "locations": [ { "city": "Manhasset", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04447872" }, { "nct_id": "NCT03649724", "title": "The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alzheimer Disease", "Mild Cognitive Impairment" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Eligard 22.5Mg Suspension for Injection", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Weill Medical College of Cornell University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": "120 Years", "sex": "FEMALE", "summary": "60 Years to 120 Years · Female only" }, "enrollment_count": 180, "start_date": "2020-11-27", "completion_date": "2026-07-25", "has_results": false, "last_update_posted_date": "2026-06-16", "last_synced_at": "2026-09-02T11:15:06.745Z", "location_count": 3, "location_summary": "Boca Raton, Florida • New York, New York • Madison, Wisconsin", "locations": [ { "city": "Boca Raton", "state": "Florida" }, { "city": "New York", "state": "New York" }, { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT03649724" } ] }