{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Manipulation&page=21",
    "query": {
      "intervention": "Manipulation",
      "page": 21
    },
    "page_size": 10
  },
  "pagination": {
    "page": 21,
    "page_size": 10,
    "total_count": 702,
    "total_pages": 71,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Manipulation&page=22&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Manipulation&page=20&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-22T13:21:01.161Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05953194",
      "title": "Effects of Sugary Drinks Counter-marketing Messages",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Weight Prejudice",
        "Weight Gain",
        "Dietary Habits"
      ],
      "interventions": [
        {
          "name": "Exposure to counter-marketing messages",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exposure to traditional health messages",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exposure to control (neutral) messages",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2184,
      "start_date": "2023-08-07",
      "completion_date": "2023-08-07",
      "has_results": false,
      "last_update_posted_date": "2024-02-28",
      "last_synced_at": "2026-10-22T13:21:01.161Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05953194"
    },
    {
      "nct_id": "NCT00011583",
      "title": "Robot Assisted Upper Limb Neuro-Rehabilitation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Stroke"
      ],
      "interventions": [
        {
          "name": "Robot-assisted therapy",
          "type": "DEVICE"
        },
        {
          "name": "Traditional therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2000-01",
      "completion_date": "2003-12",
      "has_results": false,
      "last_update_posted_date": "2008-03-11",
      "last_synced_at": "2026-10-22T13:21:01.161Z",
      "location_count": 1,
      "location_summary": "Temple, Texas",
      "locations": [
        {
          "city": "Temple",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00011583"
    },
    {
      "nct_id": "NCT06766279",
      "title": "Investigating the Efficacy of OMT to Recover Olfactory Perception After COVID-19",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anosmia"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Treatment",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham treatment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Burrell College of Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2024-08-29",
      "completion_date": "2025-08",
      "has_results": false,
      "last_update_posted_date": "2025-01-09",
      "last_synced_at": "2026-10-22T13:21:01.161Z",
      "location_count": 1,
      "location_summary": "Las Cruces, New Mexico",
      "locations": [
        {
          "city": "Las Cruces",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06766279"
    },
    {
      "nct_id": "NCT06534931",
      "title": "Effects of a Thoracic Manipulation on Hip Adductor, Extensor, and Latissimus Dorsi Force in Those With Adductor Weakness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Weakness"
      ],
      "interventions": [
        {
          "name": "High velocity low amplitude thoracic spine manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of New England",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2021-11-08",
      "completion_date": "2023-12-13",
      "has_results": false,
      "last_update_posted_date": "2024-08-02",
      "last_synced_at": "2026-10-22T13:21:01.161Z",
      "location_count": 1,
      "location_summary": "Portland, Maine",
      "locations": [
        {
          "city": "Portland",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06534931"
    },
    {
      "nct_id": "NCT01562756",
      "title": "Patient Response to Spinal Manipulation - Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "HVLA-SM",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Palmer College of Chiropractic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 6,
      "start_date": "2012-02",
      "completion_date": "2012-05",
      "has_results": true,
      "last_update_posted_date": "2017-07-31",
      "last_synced_at": "2026-10-22T13:21:01.161Z",
      "location_count": 1,
      "location_summary": "Davenport, Iowa",
      "locations": [
        {
          "city": "Davenport",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01562756"
    },
    {
      "nct_id": "NCT05684094",
      "title": "Mechanisms of Risky Alcohol Use in Young Adults: Linking Sleep to Reward- and Stress-Related Brain Function",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Use Disorder"
      ],
      "interventions": [
        {
          "name": "Sleep extension and advance",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Regular sleep duration and timing",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Oregon",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "18 Years to 24 Years"
      },
      "enrollment_count": 90,
      "start_date": "2023-09-07",
      "completion_date": "2027-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-10-22T13:21:01.161Z",
      "location_count": 1,
      "location_summary": "Eugene, Oregon",
      "locations": [
        {
          "city": "Eugene",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05684094"
    },
    {
      "nct_id": "NCT01226121",
      "title": "Safety and Efficacy of Delayed Manipulation After Xiaflex Treatment in Subjects With Dupuytren's Contracture",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dupuytren's Disease"
      ],
      "interventions": [
        {
          "name": "Clostridial collagenase injectable",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Indiana Hand to Shoulder Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 37,
      "start_date": "2010-12",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2014-06-16",
      "last_synced_at": "2026-10-22T13:21:01.161Z",
      "location_count": 2,
      "location_summary": "Indianaplis, Indiana • Stony Brook, New York",
      "locations": [
        {
          "city": "Indianaplis",
          "state": "Indiana"
        },
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01226121"
    },
    {
      "nct_id": "NCT03442894",
      "title": "Dry Needling for Sub Acromial Pain Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Subacromial Impingement Syndrome"
      ],
      "interventions": [
        {
          "name": "Standard Physical Therapy Treatment",
          "type": "PROCEDURE"
        },
        {
          "name": "Dry Needling",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham Dry Needling",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "59th Medical Wing",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 121,
      "start_date": "2018-03-06",
      "completion_date": "2022-08-20",
      "has_results": false,
      "last_update_posted_date": "2025-07-24",
      "last_synced_at": "2026-10-22T13:21:01.161Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03442894"
    },
    {
      "nct_id": "NCT06986122",
      "title": "Virtual Contexts for Affective Modulation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain Control",
        "Anxiety",
        "Memory"
      ],
      "interventions": [
        {
          "name": "Pain Threat Manipulation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pain Controllability Manipulation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Trustees of Dartmouth College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 20,
      "start_date": "2025-10-28",
      "completion_date": "2029-06-15",
      "has_results": false,
      "last_update_posted_date": "2025-10-31",
      "last_synced_at": "2026-10-22T13:21:01.161Z",
      "location_count": 1,
      "location_summary": "Hanover, New Hampshire",
      "locations": [
        {
          "city": "Hanover",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06986122"
    },
    {
      "nct_id": "NCT06987786",
      "title": "Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spine",
        "Low Back Pain",
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "Massage",
          "type": "OTHER"
        },
        {
          "name": "Talk-based therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2026-12-01",
      "completion_date": "2027-10-30",
      "has_results": false,
      "last_update_posted_date": "2026-10-16",
      "last_synced_at": "2026-10-22T13:21:01.161Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06987786"
    }
  ]
}